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Tools

The Canadian Agency for Drugs and Technologies in Health (CADTH) offers tools to assist with implementing its recommendations on optimal second-line therapies for patients with diabetes inadequately controlled on metformin, and third-line therapies for patients with diabetes inadequately controlled on metformin and sulfonylurea. The tools provide summaries of key clinical messages designed to support decision-making.

To make these tools relevant to different audiences, CADTH can tailor specific tools to individual needs and settings. Contact us if you would like our assistance in tailoring any of these tools to meet your unique needs as a health care provider, policy-maker, or consumer.

To help decision-makers evaluate optimal use initiatives, CADTH has also developed a series of generic tools that can be applied across health topics. These generic tools include an audit and feedback guide, an evaluation framework, and academic detailing templates.

Second- and Third-line Therapy Tools

  • A CADTH review, “Second-line therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy:  A systematic review and mixed treatment comparisons meta-analysis,” has been published in a wiki version in Open Medicine. This is an innovative way for readers to comment and contribute using wiki technology. The wiki can be viewed at http://livewiki.openmedicine.ca/Main_Page
  • Optimal Therapy Newsletter – summary of key clinical messages on second- and third-line therapy in type 2 diabetes, designed to support decision making by health care professionals.

Published Articles

Cost-effectiveness of second-line antihyperglycemic therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin

 (Canadian Medical Association Journal)

Second-line therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A systematic review and mixed treatment comparisons meta-analysis

(Open Medicine)

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