CDR Update — Issue 67

January 27, 2010

In This Issue

CEDAC Announcements

The Canadian Agency for Drugs and Technologies in Health (CADTH) is pleased to announce the appointment of Dr. Douglas Coyle to the Canadian Expert Drug Advisory Committee (CEDAC), effective January 2010.

Dr. Coyle is a Professor and the Director of Graduate Studies in the Department of Epidemiology and Community Medicine at the University of Ottawa. He is also a Senior Scientist at the Ottawa Hospital Research Institute.  He has been a member of the Ontario Committee to Evaluate Drugs since 2006 and the Ontario Drugs for Rare Diseases Working Group since 2008.

CADTH would also like to announce that the following members were reappointed to CEDAC: Dr. Anne Holbrook (Vice-Chair), Mr. Brad Neubauer, Dr. Bruce Carleton, Dr. Kelly Zarnke, and Dr. Lindsay Nicolle.

CADTH sincerely thanks Dr. Michael Evans, who left the committee in October 2009, for his contributions to the committee.

The biographies and conflict of interest disclosure statements for all CEDAC members are posted on the CEDAC page of CADTH’s website.

CEDAC Recommendations ― October 1 to December 31, 2009

The following formulary listing recommendations and a subsequent entry biologic (SEB) advice document were issued through the CDR program and posted on the CADTH website between October 1, 2009 and December 31, 2009.

CEDAC Recommendations

Drug Name
(Brand Name)

Submission Type

Indication

(Condition)

Recommendation Release Date

CEDAC Final Recommendation or Advice SEB

Lisdexamfetamine dimesylate
(Vyvanse)

Initial

Attention deficit hyperactivity disorder

2009-12-18

Do not list

Clostridium botulinum neurotoxin type A, free from complexing proteins
(Xeomin)

Initial

Cervical dystonia

2009-12-16

List in a similar manner

Clostridium botulinum neurotoxin type A, free from complexing proteins
(Xeomin)

Initial

Blepharospasm

2009-12-16

List in a similar manner

Clostridium botulinum neurotoxin type A, free from complexing proteins
(Xeomin)

Initial

Post-stroke spasticity of the upper limb

2009-12-16

Do not list

Eplerenone
(Inspra)

Initial

Post myocardial infarction, to reduce the risk of mortality

2009-11-25

Do not list

Glatiramer acetate
(Copaxone)

New indication

Clinically isolated syndrome (CIS), suggestive of multiple sclerosis

 

2009-11-25

Do not list

Darunavir
(Prezista)

New indication

HIV — treatment-naive

2009-10-14

List with criteria/condition

Pilot Project Subsequent Entry Biologics

Somatropin
(rDNA origin)
(Omnitrope)

Initial

Growth hormone deficiency in children and adults

2009-12-16

Advice — SEB

CEDAC = Canadian Expert Drug Advisory Committee; SEB = Subsequent Entry Biologic