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  1. Inpatient Treatment for Borderline Personality Disorder: A Review of Clinical Effectiveness and Guidelines

    September 3, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical effectiveness of inpatient treatment of adult patients with borderline personality disorder?
    2. What are the guidelines and criteria for admission and inpatient treatment of adult patients with borderline personality disorder?
    Level2

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  2. Automated Medication Dispensing Systems: Clinical Benefits and Harms and Cost-Effectiveness

    September 2, 2010

    Research TypeDevices and Systems
    Question1. What are the clinical benefits and harms of automated medication dispensing systems in hospitals?

    2. What is the cost-effectiveness of automated medication dispensing systems in hospitals?
    Level1

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  3. Estimated Glomerular Filtration Rate Calculations: Indications and Guidelines for Use

    September 2, 2010

    Research TypeDevices and Systems
    Question1. What is the evidence that a disclaimer for routine estimated glomerular filtration rate testing should be used for patients with compromised health?
    2. What is the comparative reliability of the 24 hour creatinine and creatinine clearance tests versus estimated glomerular filtration rates?
    3. What are the guidelines for the use of 24 hour creatinine and creatinine clearance tests versus estimated glomerular filtration rates?
    Level1.5

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  4. Intraosseous Infusions for Patients Needing Emergency Fluid Resuscitation or Medication Administration: Clinical Benefits, Clinical Harms, and Guidelines

    September 1, 2010

    Research TypeDrugs
    Question1. What are the clinical benefits and harms of intraosseous infusions in patients needing emergency fluid resuscitation and/or medication administration?
    2. What are the guidelines for the initiation of intraosseous infusions in patients needing emergency fluid resuscitation and/or medication administration?
    Level1.5

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  5. Cervical Cancer Screening: A Review of a Cost Feasibility Study and Jurisdictional Survey

    August 31, 2010

    Research TypeDevices and Systems
    Question1. To examine the cervical cancer screening programs in the Canadian jurisdictions, how they were implemented, and the challenges of implementation
    2. To appraise the cervical cancer screening cost feasibility study provided by the requestor
    Level2

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  6. Hip Protectors in Long-Term Care: A Review of the Comparative Clinical and Cost-Effectiveness

    August 31, 2010

    Research TypeDevices and Systems
    Question1. What is the comparative clinical effectiveness of hip protectors to prevent injuries for residents in long-term care facilities and assisted or supervised care?
    2. What is the comparative cost-effectiveness of hip protectors to prevent injuries for residents in long-term care facilities and assisted or supervised care?
    Level2

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  7. Preoperative Skin Preparation: A Review of the Clinical Effectiveness and Guidelines

    August 31, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical effectiveness of preoperative skin preparations for the prevention of infections in patients undergoing surgery?
    2. What are the guidelines and recommendations pertaining to the preoperative skin preparation for patients undergoing surgery?
    Level2

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  8. Antivirals for Influenza: A Review of the Clinical Benefit and Harm

    August 30, 2010

    Research TypeDrugs
    Question1. What are the clinical benefits and harms of the use of antivirals for seasonal influenza?
    2. What are the clinical benefits and harms of the use of antivirals for pandemic influenza?
    3. What is the evidence for use of antivirals in specific subpopulations of patients or use of specific dosages and durations of treatment for pandemic influenza?
    Level1

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  9. Rosiglitazone and Pioglitazone for Patients with Type 2 Diabetes: Safety

    August 30, 2010

    Research TypeDrugs
    QuestionWhat is the comparative safety of rosiglitazone and pioglitazone for patients with type 2 diabetes?
    Level1.5

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  10. Alpha1-Proteinase Inhibitor Therapy for Alpha1-Antitrypsin Deficiency: A Review of the Clinical Evidence

    August 30, 2010

    Research TypeDrugs
    QuestionWhat is the current clinical evidence to support the use of alpha1-proteinase inhibitor therapy for patients with alpha-1 antitrypsin deficiency and a FEV1 less than 30% predicted?
    Level2

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  11. Frequent Use of Alcohol-Based Hand Sanitizers: Safety and Guidelines

    August 27, 2010

    Research TypeDevices and Systems
    Question1. What is the safety associated with multiple and frequent use of alcohol-based hand sanitizers?
    2. What are the guidelines associated with the frequent use of alcohol-based hand sanitizers?
    Level1.5

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  12. Failures and Defects with Endotracheal Tubes and Cuffs: Clinical Evidence

    August 27, 2010

    Research TypeDevices and Systems
    Question1. What is the incidence of failures or defects with endotracheal tubes and cuffs?
    2. What is the impact of endotracheal tube and cuff failures or defects on patient safety?
    3. What is the comparative incidence of failures or defects with different brands of endotracheal tubes and cuffs?
    4. What is the comparative safety of different brands of endotracheal tubes and cuffs?
    Level1.5

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  13. Intravenous Infusion Pumps for Transfusion of Blood Products: Clinical Effectiveness, Safety, and Guidelines

    August 26, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical effectiveness of intravenous infusion pumps for transfusion of blood products (red blood cells and intravenous immunoglobulin)?
    2. What are the guidelines for use of intravenous infusion pumps for transfusion of blood products (red blood cells and intravenous immunoglobulin)?
    Level1

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  14. Diabetes in Aboriginal Populations: Review of Guidelines for Screening and Treatment

    August 25, 2010

    Research TypeDevices and Systems
    Question1. What is the incidence and prevalence of diabetes mellitus in Aboriginal people?
    2. What are the guidelines for screening and monitoring for diabetes mellitus in Aboriginal people?
    3. What are the guidelines for pharmacological
    Level2

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  15. Negative Pressure Therapy for Patients with Non-Infected Wounds: Indications for Use and Guidelines

    August 25, 2010

    Research TypeDevices and Systems
    Question1. What are the recommended indications for use of negative pressure therapy for non-infected wounds?
    2. What are the evidence-based guidelines for the use of negative pressure therapy for non-infected wounds?
    Level1

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  16. Treatment for Adult Onset Distal Spinal Muscular Atrophy: Clinical Effectiveness and Guidelines

    August 24, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical effectiveness of various treatment options for adult onset distal spinal muscular atrophy?
    2. What are the guidelines for the treatment of adult onset distal spinal muscular atrophy?
    Level1.5

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  17. Turnaround Times for Breast Cancer Pathology Reports: Clinical Outcomes and Guidelines

    August 24, 2010

    Research TypeDevices and Systems
    Question1. What effect do delayed breast biopsy and surgical specimen pathology reports have on patient outcomes?
    2. What are the evidence-based guidelines regarding turnaround time for breast biopsy and surgical specimen pathology reports?
    Level1

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  18. Use of Patient Experience Indicators to Influence Heart Failure Care Pathways: Clinical Evidence and Guidelines

    August 24, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical evidence to support the use of patient experience indicators to influence the care of patients presenting with heart failure?
    2. What are the evidence-based guidelines for the use of patient experience indicators to influence the care of patients presenting with heart failure?
    Level1.5

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  19. Identification Bracelet Placement on Infants and Newborns: Clinical Evidence and Guidelines

    August 20, 2010

    Research TypeDevices and Systems
    Question1. What is the evidence for attached identification bracelets on hospitalized children younger than three years old to prevent misidentification?
    2. What are the guidelines for the direct limb placement of identification bracelets for hospitalized children younger than three years old?
    3. What are the guidelines for the use of other identification methods to validate the identity of hospitalized children younger than three years old?
    Level1.5

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  20. Number of Procedures to Maintain Competence for Minimally Invasive Surgery: Clinical Evidence and Guidelines

    August 20, 2010

    Research TypeDevices and Systems
    Question1. What is the clinical evidence to support a minimum number of minimally invasive procedures be performed by surgeons to maintain competence or clinical expertise?
    2. What are the evidence-based guidelines regarding a minimum number of minimally invasive surgical procedures to be performed by surgeons to maintain competence or clinical expertise?
    Level1

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