CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.
For evidence, tools, and resources related to COVID-19, visit our COVID-19 Evidence Portal.


Begin main content

Abuse and Misuse of Gabapentin: Clinical Evidence, Safety, and Guidelines

Last updated: October 19, 2017
Project Number: RB1146-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report


  1. What is the clinical evidence for the potential misuse or abuse of gabapentin?
  2. What are the harms associated with the potential misuse or abuse of gabapentin?
  3. What are the evidence-based guidelines regarding managing patients abusing gabapentin?

Key Message

Three systematic reviews and three non-randomized studies were identified regarding the potential abuse and misuse of gabapentin.