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Anal Cancer Screening in High Risk Populations: Clinical Effectiveness, Diagnostic Accuracy, Cost-Effectiveness, and Guidelines

Last updated: September 20, 2019
Project Number: RB1400-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical utility of anal cancer screening in high risk populations?
  2. What is the diagnostic accuracy of Pap testing for anal cancer in high risk populations?
  3. What is the cost-effectiveness of anal cancer screening in high risk populations?
  4. What are the evidence-based guidelines for anal cancer screening in high risk populations?

Key Message

Four systematic reviews (all with meta-analyses) were identified regarding the diagnostic accuracy of Pap testing for anal cancer in high risk populations. One economic evaluation was identified regarding the cost-effectiveness of anal cancer screening in high risk populations. Three evidence-based guidelines were identified regarding the use of anal cancer screening in high risk populations. No relevant health technology assessments, systematic reviews, meta-analyses, or randomized controlled trials were identified regarding the clinical utility of anal cancer screening in high risk populations.