CADTH | Evidence Driven
CADTH | Evidence Driven

Antiviral Treatment for COVID-19 in Adults with Renal Impairment

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1242-000
Effective finish date:

Question

  1. What is the clinical effectiveness of nirmatrelvir and ritonavir for COVID-19 in adults with renal impairment?
  2. What is the clinical effectiveness of remdesivir for COVID-19 in adults with renal impairment?
  3. What are the evidence-based guidelines for the use of nirmatrelvir and ritonavir for COVID-19 in adults with renal impairment?
  4. What are the evidence-based guidelines for the use of remdesivir for COVID-19 in adults with renal impairment?

Key Message

  • We did not find any studies about the clinical effectiveness of nirmatrelvir and ritonavir for COVID-19 in adults with renal impairment.
  • We found 1 systematic review and 7 non-randomized studies about the clinical effectiveness of remdesivir for COVID-19 in adults with renal impairment.
  • We did not find any evidence-based guidelines for the use of nirmatrelvir and ritonavir for COVID-19 in adults with renal impairment.
  • We found 1 evidence-based guideline for the use of remdesivir for COVID-19 in adults with renal impairment.

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Antiviral Treatment for COVID-19 in Adults with Renal Impairment View PDF
Last Updated : November 29, 2022