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Calcium and Vitamin D Supplementation for Adults: Safety and Guidelines

Last updated: June 7, 2018
Project Number: RB1229-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report


  1. What is the clinical evidence for the safety of calcium and vitamin D supplementation in adults?
  2. What are the evidence-based guidelines regarding the use of calcium and vitamin D supplements in the general adult population?

Key Message

Thirteen systematic reviews (seven with meta-analyses), 30 randomized controlled trials, and seven evidence based guidelines were identified regarding calcium and vitamin D supplementation in adults.