Chitosan-Based Scaffolds During Orthopedic Surgery in Adults: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

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Project Status:
Completed
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Summary of Abstracts
Project Number:
RB1426-000

Question

  1. What is the clinical effectiveness of using chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss?
  2. What is the cost-effectiveness of using chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss?
  3. What are the evidence-based guidelines regarding the use of chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss?

Key Message

One systematic review, two randomized controlled trials, and one non-randomized study were identified regarding the clinical effectiveness of using chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss in the knee. One economic evaluation was identified regarding the cost-effectiveness of using chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss in the knee. No relevant evidence-based guidelines were identified regarding the use of chitosan-based scaffolds during orthopedic surgery in patients with cartilage loss in the knees or hips.