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Codeine Compared with Other Opioids for Pain Relief in Pediatric Patients: Comparative Clinical Effectiveness, Safety, and Guidelines

Last updated: February 19, 2013
Project Number: RB0567-000
Product Line: Rapid Response
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the evidence for the clinical effectiveness of codeine compared with other opioids for pain relief in pediatric patients?
  2. What is the evidence for the safety of codeine compared with other opioids when administered to pediatric patients?
  3. What are the guidelines regarding the use of codeine compared with other opioids for pain relief in pediatric patients?

Key Message

Two non-randomized studies were identified regarding the use of codeine compared with other opioids for pain relief in pediatric patients. No evidence-based guidelines were identified regarding the use of codeine compared with other opioids for pain relief in pediatric patients.