- What is the clinical evidence on the risk of serious adverse events associated with combination benzodiazepine-opioid use for adults with chronic non-cancer pain?
- What is the comparative efficacy and safety of combination benzodiazepine-opioid use compared with opioids alone for chronic non-cancer pain with or without comorbidity?
- What is the comparative clinical evidence on different benzodiazepine-opioid treatment strategies?
- What are the evidence-based guidelines regarding combination benzodiazepine-opioid use?
One systematic review, two non-randomized studies, and three evidence-based guidelines were identified regarding combination benzodiazepine-opioid use.
analgesics, anesthesia, benzodiazepines, chronic pain, maximum tolerated dose, narcotics, Dose-Response Relationship, Drug, Opioid