Copper and Ceruloplasmin Tests for Children With Global Developmental Delay and Intellectual Disability

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Project Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1467-000
Effective finish date:

Question

  1. What is the diagnostic test accuracy of copper and ceruloplasmin tests (to detect Wilson disease and/or Menkes disease) for children with global development delay and intellectual disability?
  2. What is the clinical utility of copper and ceruloplasmin tests for children with global development delay and intellectual disability?
  3. What are the evidence-based guidelines regarding the use of copper and ceruloplasmin tests for children with global development delay and intellectual disability?

Key Message

No evidence was identified regarding the diagnostic test accuracy or clinical utility of copper and ceruloplasmin tests compared to other tests or criteria to detect Wilson disease and Menkes disease in children with global development delay and intellectual disability that met the criteria for this review.

No evidence-based guidelines were found on the use of copper and ceruloplasmin tests for children with global developmental delay and intellectual disability that met the criteria for this review.