Browse the Evidence

• Diabetic Foot Ulcers
• Insulin Therapy
• Monitoring of Blood Glucose
• Second- and Third-Line Therapy
• Other Diabetes Reports

Diabetic Foot Ulcers

• Compression Therapy in Diabetic Foot Ulcer Management: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines (Summary With Critical Appraisal, October 2014)
• Screening and Risk Stratification for Diabetic Foot Ulcers: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Summary With Critical Appraisal, October 2014)
• Debridement Procedures for Managing Diabetic Foot Ulcers: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Summary With Critical Appraisal, September 2014)
• Removable Off-Loading Devices for Diabetic Foot Ulcers: A Review of Clinical and Cost-Effectiveness (Summary With Critical Appraisal, September 2014)
• Negative Pressure Wound Therapy for Managing Diabetic Foot Ulcers: A Review of the Clinical Effectiveness, Cost-effectiveness, and Guidelines (Summary With Critical Appraisal, August 2014)
• Optimal Care of Chronic, Non-Healing, Lower Extremity Wounds: A Review of Clinical Evidence and Guidelines (Summary With Critical Appraisal, December 2013)
• Delivery of Podiatry Care for Adults With Diabetes or Chronic Foot Conditions: A Review of the Clinical Effectiveness (Summary With Critical Appraisal, November 2013)
• Negative Pressure Wound Therapy for Patients with Diabetic Foot Ulcers and Pressure Ulcers: Clinical Effectiveness (Summary With Critical Appraisal, June 2012)
• Topical Antimicrobials and Antimicrobial Dressings for the Management of Diabetic Foot Ulcers: Clinical Effectiveness and Guidelines (Summary of Abstracts, September 2014)
• Total Contact Casts for Diabetic Foot Ulcers: Cost-Effectiveness (Summary of Abstracts, June 2013)
• Educational Strategies for Prevention of Diabetic Foot Complications: Clinical Evidence and Guidelines (Summary of Abstracts, February 2011)

Insulin Therapy

• Insulin degludec (Tresiba) for type 1 and 2 diabetes (Drug Review Recommendation, November 2017)
• Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes? (Issues in Emerging Health Technologies, January 2018)
• Afrezza Inhaled Insulin for Diabetes Mellitus (Issues in Emerging Health Technologies, January 2013)
• Insulin Analogue Therapy for Diabetes Management (Optimal Use Project)
• Second- and Third-Line Therapy for Patients With Diabetes (Optimal Use Project)
• Basal-Bolus Versus Sliding-Scale Insulin Therapy in the Acute Care Hospital Setting: A Review of Comparative Clinical Effectiveness and Cost-Effectiveness (Summary with Critical Appraisal, January 2017)
• Insulin Pumps for Adults with Type 1 Diabetes: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Summary with Critical Appraisal, December 2015)
• Insulin Pens in Acute Care Settings: Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Summary of Abstracts, July 2017)
• The Management of Insulin Administration and Blood Glucose Monitoring in Children with Type 1 Diabetes Mellitus: Guidelines (Summary of Abstracts, May 2017)
• Insulin Pens in Acute Care Settings: Safety, Cost-Effectiveness, and Guidelines (Summary of Abstracts, March 2015)
• Combination Use of Insulin and Dipeptidyl Peptidase-4 (DPP-4) Inhibitors in Type 2 Diabetes: Clinical Effectiveness (Summary of Abstracts, July 2014)
• Standing Orders for Insulin Administration in Hospitalized Patients With Type 1 or Type 2 Diabetes: Clinical Evidence (Summary of Abstracts, July 2014)
• Continuous Subcutaneous Insulin Infusion for Type 1 Diabetes: Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Reference List, April 2015)

Monitoring of Blood Glucose

• Self-Monitoring of Blood Glucose (Optimal Use Project)
• Flash Glucose Monitoring System for Diabetes (Issues in Emerging Health Technologies, March 2018)
• Self-Monitoring of Blood Glucose Frequency for Patients with Hypoglycemia Unawareness: A Review of Clinical Effectiveness and Guidelines  (Summary with Critical Appraisal, April 2017)
• Increasing Frequency of Self-Monitoring Blood Glucose Test Strips During Pregnancy: A Review of the Clinical and Cost-Effectiveness and Guidelines (Summary with Critical Appraisal, April 2017)
• HbA1c Testing Frequency: A Review of the Clinical Evidence and Guidelines (Summary With Critical Appraisal, September 2014)
• Blood Glucose Monitors and Test Strips: A Review of the Comparative Clinical Evidence and Cost-Effectiveness — An Update (Summary With Critical Appraisal, March 2013)
• Continuous Glucose Monitoring Systems for Pediatric Patients with Type 1 Diabetes: Clinical and Cost-Effectiveness (Summary of Abstracts, December 2016)
• Glucose Replacement Agents in Frail Elderly Patients With Type 2 Diabetes in Long-Term Care: Clinical and Cost-Effectiveness, Harms, and Guidelines (Summary of Abstracts, January 2015)
• Postprandial Glucose Measurements in Patients with Diabetes: Clinical Effectiveness and Guidelines (Reference List, February 2015)

Second- and Third-Line Therapy

• Second-Line Therapy for Patients with Type 2 Diabetes (Therapeutic Review Project, May 2017)
• Second and Third-Line Therapy for Patients with Diabetes (Optimal Use project, July 2013)
• Cardiovascular Outcomes with Sodium-glucose Co-transporter 2 Inhibitors: A Review of the Clinical Evidence (Summary with Critical Appraisal, November 2015)
• Lixisenatide (Adlyxine) (Drug Review Recommendation, July 2017)
• Dapagliflozin (Forxiga) (Drug Review Recommendation, November 2015)
• Empagliflozing (Jardiance) (Drug Review Recommendation, October 2016)
• Empagliflozin (Jardiance) (Drug Review Recommendation, October 2015)
• Alogliptin (Nesina) for Type 2 Diabetes Mellitus (Drug Review Recommendation, January 2015)
• Alogliptin Plus Metformin (Kazano) for Type 2 Diabetes Mellitus (Drug Review Recommendation, January 2015)
• Canagliflozin (Invokana) for Type 2 Diabetes Mellitus (Drug Review Recommendation, January 2015)
• Saxagliptin + Metformin (Komboglyze) for Type 2 Diabetes Mellitus (Drug Review Recommendation, June 2014)
• Exenatide (Byetta) (Drug Review Recommendation, July 2012)

Other Diabetes Reports

• Management of Diabetes in Long-Term Care Facilities: Guidelines (Summary of Abstracts, June 2018)
• Diabetes Horizon Scan Bundle (Issues in Emerging Health Technologies, July 2017)
• Bariatric Surgery for the Long-Term Treatment of Obesity: A Review of the Clinical Effectiveness and Cost-Effectiveness (Summary with Critical Appraisal, July 2016)
• Aflibercept (Eylea) for Diabetic Macular Edema (Drug Review Recommendation, May 2015)
• Ranibizumab (Lucentis) for Myopic Choroidal Neovascularization (Drug Review Recommendation, February 2014)
• Long-term Nabilone Use: A Review of the Clinical Effectiveness and Safety (Summary With Critical Appraisal, October 2015)
• Diabetic Diets for Frail Elderly Long-Term Care Residents With Type 2 Diabetes Mellitus: A Review of Guidelines (Summary With Critical Appraisal, December 2014)
• Islet Cell Transplantation in Patients with Unstable Diabetes: A Review of Clinical- and Cost-Effectiveness and Guidelines (Summary With Critical Appraisal, December 2014)
• Obesity Interventions Delivered in Primary Care for Patients with Diabetes: A Review of Clinical Effectiveness (Summary With Critical Appraisal, June 2014)
• Group Care for Chronic Disease Management: A Review of the Clinical Effectiveness, Cost-Effectiveness, and Guidelines (Summary With Critical Appraisal, November 2013)
• Management of Diabetes in the Long-Term Care Population: A Review of Guidelines (Summary With Critical Appraisal, November 2015)
• Low Carbohydrate Diet Interventions for Diabetes: Clinical Effectiveness and Guidelines (Summary of Abstracts, April 2017)
• Motivational Interviewing Following Pre-Diabetes Diagnosis: Clinical Effectiveness (Summary of Abstracts, January 2013)
• Diabetes Screening for Asymptomatic Adults: A Review of the Diagnostic Accuracy, Cost Effectiveness, and Guidelines (Summary of Abstracts, December 2013)
• Drug Therapies for Immunosuppression in Adult Patients Following Islet Cell Transplantation for the Treatment of Diabetes: Clinical and Cost-Effectiveness (Summary of Abstracts, March 2013)