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Chemistry
- Non-Invasive Serum Markers for the Diagnosis and Monitoring of Liver Fibrosis: Diagnostic Accuracy, Clinical Effectiveness/Utility, Cost-Effectiveness, and Guidelines (CADTH Reference List, August 2017)
- Routine Prenatal Thyroid-Stimulating Hormone Testing: Evidence-Based Guidelines (CADTH Summary of Abstracts, November 2016)
- Comparative Value of Erythrocyte Sedimentation Rate and C-Reactive Protein Testing in Combination Versus Individually for the Diagnosis of Undifferentiated Patients With Suspected Inflammatory Disease or Serious Infection: A Systematic Review and Economic Analysis (CADTH Health Technology Assessment, November 2015)
- Serum IgM and Molecular Tests for Mycoplasma pneumoniae Detection: A Review of Diagnostic Test Accuracy, Clinical Effectiveness, Cost-Effectiveness, and Guidelines (CADTH Summary with Critical Appraisal, November 2015)
- Free T3 or T4 Levels for Hypothyroidism: Clinical Effectiveness and Guidelines (CADTH Summary of Abstracts, May 2015)
- Emerging Predictive Serum Biomarkers for Cardiovascular Disease: Clinical Effectiveness, Diagnostic Accuracy, and Guidelines (CADTH Reference List, Apr. 2015)
- Antinuclear Antibody Testing for Systemic Lupus Erythematosus or Connective Tissue Disease: Clinical Effectiveness and Guidelines (CADTH Summary of Abstracts, Mar. 2015)
- NephroCheck: A Bedside Biomarker Test to Identify Patients at Risk for Acute Kidney Injury (CADTH Issues in Emerging Health Technologies, Mar. 2015)
- Testosterone in Men with Erectile Dysfunction With No Symptoms of Hypogonadism: Clinical Effectiveness and Guidelines (CADTH Summary of Abstracts, Mar. 2015)
- Protein Testing in Patients With Multiple Myeloma: A Review of Clinical Effectiveness and Guidelines (CADTH Summary with Critical Appraisal, January 2015)
- Fibroblast Growth Factor 23 (FGF-23) Assay (INESSS Report, December 2014)
- Linezolid Assay Using High Performance Liquid Chromatography (HPLC-DAD) (INESSS Report, December 2014)
- Plasma 3-Methoxytyramine Assay Using LC-MS/MS (INESSS Report, December 2014)
- Immunoserological Profile of Autoimmune Skin Diseases (INESSS Report, August 2014)
- Measurement of Total Bile Acids (INESSS Report, August 2014)
- Quantitative Assay of Topiramate by LC-MS/MS (INESSS Report, July 2014)
- Serum Biomarkers to Diagnose Mild Traumatic Brain Injury in Adults (CADTH Issues in Emerging Health Technologies, December 2013)
- Serum Levetiracetam Quantitation Using LC-MS/MS (INESSS Report, December 2013)
- Routine Blood Tests for Patients in the Intensive Care Unit (CADTH Summary of Abstracts, August 2013)
- Acylcarnitines and Amino Acids Quantification in Dried Blood Spots Using MS/MS (43 Diseases) (INESSS Report, April 2013)
- Magnesium Lab Testing for Heart Failure (CADTH Summary of Abstracts, March 2012)
- JC Virus Antibody Testing for Patients with MS (CADTH Summary with Critical Appraisal, March 2013)
- Blood Glucose and Blood Pressure Measurement for Newborns (CADTH Summary of Abstracts, December 2010)
- Serum Anti-GAD (December 2010)
- Live Blood Analysis for the Diagnosis of Various Disease Conditions (CADTH Rapid Response, April 2009)
Cytology
- Urgent, Non-Screening Fecal Occult Blood Testing for Patients with Suspected Gastrointestinal Bleeding: A Review of Clinical Effectiveness and Guidelines (CADTH Summary With Critical Appraisal, January 2017)
- Human Papillomavirus Testing for Cervical Cancer Screening: Clinical Effectiveness, Cost-Effectiveness and Guidelines (CADTH Reference List, Oct. 2016)
- Guaiac Fecal Occult Blood Test Compared with Alternative Tests for Patients with Unexplained Anemia or Suspected Colorectal Cancer: Comparative Clinical Utility, Cost-Effectiveness, and Evidence-Based Guidelines (CADTH Summary of Abstracts, July 2016)
- Self-Collected Versus Clinician Collected Samples for Sexually Transmitted Infection Testing in Women: A Review of Comparative Clinical Effectiveness Cost-Effectiveness, and Guidelines (CADTH Summary With Critical Appraisal, June 2016)
- Screening for Shiga-toxigenic Escherichia coli in Clinical Fecal Samples: Diagnostic Accuracy, Clinical Utility, and Guidelines (CADTH Reference List, May 2015)
- Detection of Anti-Glutamate Receptor (NMDA) (INESSS Report, December 2014)
- Fecal Calprotectin Assay (INESSS Report, July 2014)
- Genotyping of Cytomegalovirus (or Herpes Simplex Virus) for Ganciclovir (Aciclovir) and Foscarnet Resistance (INESSS Report, December 2013)
- Fecal DNA Tests, Next Generation (CADTH Environmental Scan, June 2010)
- Fecal Immunochemical Tests for Colorectal Cancer Screening (CADTH Reference List, October 2009)
Hematology
- Fetal Scalp Lactate Testing During Intrapartum Pregnancy with Abnormal Fetal Heart Rate: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (CADTH Summary With Critical Appraisal, March 2018)
- Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism (CADTH Optimal Use project)
- Frequency of Prothrombin Time and International Normalized Ratio Testing: Guidelines (CADTH Summary of Abstracts, January 2018)
- Recognition and Diagnosis of Sepsis in Rural or Remote Areas: Clinical and Cost-Effectiveness and Guidelines (CADTH Reference List, January 2018)
- Point-Of-Care D-Dimer Testing: A Review of Diagnostic Accuracy, Clinical Utility, and Safety (CADTH Summary With Critical Appraisal, November 2017)
- Transcutaneous Bilirubin Measurements in Newborns: Clinical and Cost-Effectiveness, and Guidelines (CADTH Summary of Abstracts, November 2017)
- Screening and Treatment for Patients with NS5A Resistance-Associated Variants of Hepatitis C Virus: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (CADTH Summary with Critical Appraisal, June 2016)
- Screening for Hepatitis C: A Systematic Review and Meta-analysis (CADTH Health Technology Assessment)
- Point of Care Tests for Infectious Diseases: Review of Clinical and Cost-Effectiveness, and Guidelines (CADTH Summary with Critical Appraisal, March 2016)
- Point-of-Care Troponin Testing in Patients with Symptoms Suggestive of Acute Coronary Syndrome (CADTH Optimal Use project)
- Folate Testing: A Review of the Diagnostic Accuracy, Clinical Utility, Cost-Effectiveness, and Guidelines (CADTH Summary With Critical Appraisal, July 2015)
- Folate Testing: Diagnostic Accuracy, Clinical Effectiveness and Guidelines (CADTH Reference List, May 2015)
- Routine Troponin Testing: Clinical Evidence, Cost-Effectiveness, and Guidelines (CADTH Reference List, January 2015)
- Vitamin B12 Testing in the General Population: Clinical and Cost-Effectiveness and Guidelines (CADTH Summary of Abstracts, January 2015)
- Vitamin D Testing in the General Population: A Review (CADTH Summary with Critical Appraisal, January 2015)
- Vitamin D Testing in the General Population: Clinical and Cost-Effectiveness and Guidelines (CADTH Reference List, December 2014)
- Factor V Leiden and Prothrombin Mutation Testing in Patients With Unprovoked Thromboembolism (CADTH Optimal Use Project, August 2014)
- Measurement of Direct Anti-Xa Activity of Rivaroxaban (INESSS Report, July 2014)
- Point-of-Care Testing of the International Normalized Ratio (CADTH Optimal Use Project, July 2014)
- Detection of A and B Subunits of Factor XIII and Detection of an Anti-Factor XIII by ELISA (INESSS Report, June 2014)
- Eosin-5’-Maleimide (EMA) Test for Hereditary Spherocytosis (INESSS Report, June 2014)
- Lamellar Body Count (INESSS Report, December 2013)
- Measurement of Direct Anti-lla Activity of Dabigatran (INESSS Report, December 2013)
- Measurement of Ribavirin Using HPLC-UV (INESSS Report, December 2013)
- TNF-a Assay by ELIZA after TLR-2 and TLR-4 Stimulation (December 2013)
- Detection of Infliximab and Anti-Infliximab Antibodies with ELISA or HPLC (INESSS Report, August 2013)
- Anti-Sa Analysis Using ELISA (INESSS Report, April 2013)
- ADAMTS-13 Activity Measurement Using Fluorescence Resonance Energy Transfer (FRET) (INESSS Report, March 2013)
- Point-of-Care Versus Lab Troponin Testing for Diagnosis of Acute Coronary Syndrome (CADTH Summary with Critical Appraisal, October 2012)
- High-Sensitivity Cardiac Troponin for the Rapid Diagnosis of Acute Coronary Syndrome in the ER (CADTH Optimal Use Project, July 2012)
- Tuberculosis: Interferon-Gamma Release Assays Testing vs. Skin Testing (CADTH Summary with Critical Appraisal, May 2011)
Microbiology
- Recognition and Diagnosis of Sepsis in Adults: Evidence-Based Guidelines (CADTH Summary of Abstracts, January 2018)
- A Rapid Test for Microbial Identification in Patients With Suspected Sepsis (CADTH Issues in Emerging Health Technologies, September 2017)
- Diagnostic Tests for Group A Streptococcal Infection: Clinical and Cost-Effectiveness and Guidelines (CADTH Reference List, August 2017)
- Three- Versus Five-Part Differential Complete Blood Count Testing for Patients in the Emergency Department: A Review of Comparative Diagnostic Accuracy, Safety, and Evidence-Based Guidelines (CADTH Summary With Critical Appraisal, Aug. 2016)
- Streptococcal Antigen Test for Pneumonia Detection: A Review of Clinical and Cost-Effectiveness and Guidelines (CADTH Summary with Critical Appraisal, November 2015)
- MALDI-TOF Mass Spectrometry for Pathogen Identification: A Review of Accuracy and Clinical Effectiveness (CADTH Peer-Reviewed Summary with Critical Appraisal, October 2015)
- Stool Antigen Tests for Helicobacter pylori Infection: A Review of Clinical and Cost-Effectiveness and Guidelines (CADTH Summary with Critical Appraisal, January 2015)
- Frequency of Rescreening of Patients Negative for Antibiotic Resistant Organisms: Clinical Evidence and Guidelines (CADTH Summary of Abstracts, December 2014)
- Detection of S. Pneumoniae, N. Meningitidis, S. Agalactiae, L. Monocytogenes and H. Influenzae Type B Using NAAT of Cerebrospinal Fluid (INESSS Report, December 2013)
- MRSA Screening and Discontinuation of Precautions in Hospitals (CADTH Summary of Abstracts, June 2011)
- Universal Screening for Antibiotic-Resistant Organisms in Long-Term Care Facilities: Clinical Effectiveness and Guidelines (CADTH Reference List, December 2014)
- Carbon-13 Urea Breath Test by Isotope Ratio Mass Spectrometry to Detect H. pylori (INESSS Report, December 2013)
- Carbon-13 Urea Breath Test with Infrared Spectrometry for Detection of H. pylori (INESSS Report, December 2013)
Molecular Diagnostics
- HPV Testing for Primary Cervical Cancer Screening (CADTH Optimal Use project in progress)
- A Gene Expression Test to Assess the Likelihood of Obstructive Coronary Artery Disease (CADTH Issues in Emerging Health Technologies, March 2018)
- Gene Expression Tests for Women with Early Stage Breast Cancer: A Review of Clinical Utility and Cost-Effectiveness (CADTH Summary With Critical Appraisal, October 2017)
- Point-of-Care Testing for Influenza: The cobas Liat System (CADTH Issues in Emerging Health Technologies bulletin, Nov. 2016)
- Non-invasive Prenatal Testing: Cost-Effectiveness and Guidelines (CADTH Reference List, February 2016)
- Detection of Targeted Mutations in Pediatric Brain Tumours (K27M and G34V/R in H3.3, K27M in H3.1, and V600E in BRAF) (INESSS Report, December 2014)
- Exploration of Intellectual Disability and Neurodegenerative Diseases With Exome Sequencing (INESSS Report, June 2014)
- Familial Aortopathy—Gene Panels (INESSS Report, August 2014)
- Familial Predisposition to Leukemia Panel: RUNX1 (AML1), PAX5, and TP53 Gene Sequencing (INESSS Report, December 2014)
- Four Recessive Diseases of Saguenay–Lac-Saint-Jean Mutations Screening (INESSS Report, June 2014)
- Gene Panel ― Noonan Syndrome (INESSS Report, June 2014)
- Gene Panel— Familial Cardiomyopathy and Arrhythmia (INESSS Report, June 2014)
- MECP2 Sequencing for Rett Syndrome (INESSS Report, December 2014)
- Mutation Analysis of the Kinase Domain of the BCR-ABL Fusion Protein (INESSS Report, December 2014)
- Mutational Analysis of Exon 9 of the CALR Gene (INESSS Report, June 2014)
- Panel of BRCA1/BRCA2 Gene Mutations — Eastern European Population (INESSS Report, June 2014)
- Sequencing of Factor VII (INESSS Report, June 2014)
- Sequencing of the Iron-Responsive Element (Ire) of the Ferritin Light Chain Gene (FTL) (INESSS Report, December 2014)
- SYNGAP1 Gene Sequencing to Detect Nonsyndromic Intellectual Disability (INESSS Report, December 2014)
- Testing of Mitochondrial DNA and Mitochondrial Respiratory Chain Complexes (INESSS Report, December 2014)
- Thyroid-Stimulating Hormone Receptor (TSHR) Gene Mutation Test by Sequencing and MLPA (INESSS Report, June 2014)
- KRAS Testing for Metastatic Colorectal Cancer Using Therascreen KRAS RGQ PRC Kit (CADTH Issues in Emerging Health Technologies, May 2014)
- Argininosuccinate Synthase (INESSS Report, December 2013)
- Array Comparative Genomic Hybridization (CADTH Summary with Critical Appraisal, December 2013)
- Breast and Pancreatic Cancer — Detecting the Q775X Allele of the Palb2 Gene Using RFLP and Detecting PALB2 Gene Mutations Using HRM and Direct Sequencing (INESSS Report, December 2013)
- Carbamoyl Phosphate Synthetase (INESSS Report, December 2013)
- Colon Cancer — Screening for Germline Mutations in MSH6 and PMS2 Genes with the Protein Truncation Test (INESSS Report, December 2013)
- Dermatofibrosarcoma Protuberans — Detecting the Translocation of the COL1A1-PDGFB Gene in T(17;22) Using RT-PCR (INESSS Report, December 2013)
- Fibrous Dysplasia — Detecting Codon 201 and 227 Mutations of the GNAS1 Gene Using Real-Time PCR (INESSS Report, December 2013)
- Genotyping of Influenza Viruses by Nucleic Acid Pyrosequencing (INESSS Report, December 2013)
- Genotyping of Influenza Viruses Using Nucleic Acid Sequencing (INESSS Report, December 2013)
- HPV Sequencing Using a Cytobrush (INESSS Report, December 2013)
- KIR Genotyping Using PCR (INESSS Report, December 2013)
- Methylmalonic Acidemia (MMAA, MMAB, MCEE, TCbIR, Mutase Genes) Individual Mutation (NAAT) (INESSS Report, December 2013)
- Protein C Gene Sequencing (INESSS Report, December 2013)
- Renal Cell Carcinoma — Detection of PRCC-TFE3 and Alpha-TFEB Gene Fusions Using RT-PCR on Tissues (INESSS Report, December 2013)
- X and Y Chromosomes (INESSS Report, December 2013)
- Carbohydrate-Deficient Transferrin (INESSS Report, April 2013)
- Codeletion of Chromosomes 1p and 19q Using FISH on a Paraffin-Embedded Section (INESSS Report, April 2013)
- EGFR/CEP7 Gene Amplification Using FISH on a Paraffin-Embedded Section (INESSS Report, April 2013)
- Genotyping of Human Papillomavirus Viruses Using Linear Array (INESSS Report, April 2013)
- HPV Genotyping Using Linear Array (INESSS Report, April 2013)
- MGMT Promoter Methylation Using Conventional PCR (INESSS Report, April 2013)
- Detecting Aneuploidy of Chromosomes 13, 18, 21, X, Y with QF-PCR (INESSS Report, December 2010)
Pathology
Toxicology
Urinalysis
- Point-of-Care Urine Pregnancy Screening in the Emergency Department: Diagnostic Accuracy, Clinical Utility, and Guidelines (CADTH Summary of Abstracts, December 2017)
- Point-of-Care Urine Testing for Suspected Urinary Tract Infections in the Emergency Department: Diagnostic Accuracy, Clinical Utility, and Guidelines (CADTH Summary of Abstracts, December 2017)
- Routine Urinalysis for Low-Risk Pregnancies: Clinical Utility and Guidelines (CADTH Summary of Abstracts, May 2017)
- Rapid Urinalysis for Detecting Urinary Tract Infections: Cost-Effectiveness (CADTH Summary of Abstracts, June 2016)
- Urine Testing in Long-Term Care: Clinical and Cost Effectiveness (CADTH Summary of Abstracts, December 2014)
- Urine Testing in Long-Term Care: Guidelines (CADTH Summary of Abstracts, December 2014)
- Urine Cytology for the Diagnosis of Urinary Tract Cancers: Comparative Effectiveness and Guidelines (INESSS Report, July 2012)
Virology
Other
- Point-of-Care Testing: Summary of Evidence (CADTH Tool, November 2017)
- Point of Care Testing: An Environmental Scan (CADTH Environmental Scan, October 2017)
- Multiplex Testing for Sexually Transmitted Infections: Diagnostic Accuracy, Clinical Utility, and Cost-Effectiveness (CADTH Summary of Abstracts, May 2017)
- Electronic Identification and Tracking Systems for the Management of Human Laboratory Samples and Donations: Clinical Effectiveness, Cost Effectiveness, and Guidelines (CADTH Reference List, Mar. 2017)
- Timing of Pre-operative Testing and Assessment: Guidelines (CADTH Summary of Abstracts, February 2016)
- Intervals and Frequency of Repeat Routine Laboratory Testing: Guidelines (CADTH Reference List, Sept. 2015)
- Initiatives to Optimize the Utilization of Laboratory Tests (CADTH Environmental Scan, October 2014)
- Techniques to Improve the Use of Diagnostic Laboratory Test Ordering: Clinical Evidence (CADTH Summary of Abstracts, March 2013)
- Pre-Operative Testing and Assessment: A Review (CADTH Summary with Critical Appraisal, October 2011)
