| Marque de commerce | Nom générique | Indication | État d'avancement du projet | Présentation reçue | Date d'émission de la recommandation |
|---|---|---|---|---|---|
| Gynazole.1 | Butoconazole nitrate | Vaginal infection | Complete | June 30, 2004 | January 26, 2005 |
| NovoMix 30 | Insulin aspart/insulin aspart protamine | Diabetes mellitus | Complete | October 13, 2005 | April 26, 2006 |
| Fosavance 70/5600 | Alendronate sodium / cholecalciferol | Osteoporosis | Complete | December 18, 2008 | June 17, 2009 |
| Abilify | Aripiprazole | Schizophrenia | Complete | November 6, 2009 | April 27, 2010 |
| Abilify | Aripiprazole | Depression, Major Depressive Disorder (MDD) | Complete | October 1, 2013 | October 22, 2014 |
| Abilify Maintena | Aripirazole | Schizophrénie | Complete | January 6, 2014 | December 19, 2014 |
| Abilify | Aripiprazole | Schizophrenia and Related Psychotic Disorders | Complete | March 29, 2011 | July 18, 2011 |
| Abstral | Fentanyl citrate | Pain, Cancer (breakthrough) | Complete | June 30, 2011 | December 16, 2011 |
| Aclasta | Zoledronic acid | Complete | July 20, 2011 | November 16, 2011 | |
| Aclasta | Zoledronic acid | Osteoporosis, postmenopausal women | Complete | November 29, 2007 | June 25, 2008 |
| Actemra | Tocilizumab | Arthritis, juvenile idiopathic | Complete | January 30, 2012 | July 19, 2012 |
| Actemra | tocilizumab | Artérite à cellules géantes (ACG) | Complete | September 25, 2017 | March 27, 2018 |
| Actemra | Tocilizumab | polyarthrite rhumatoïde | Complete | March 3, 2014 | February 19, 2015 |
| Actemra | Tocilizumab | Arthritis, Rheumatoid | Complete | May 27, 2010 | November 17, 2010 |
| Actemra | Tocilizumab | Polyarticular juvenile idiopathic arthritis | Complete | July 29, 2013 | March 19, 2014 |
| Actikerall | Fluorouracil et acide salicylique | kératose actinique hyperkératosique | Complete | August 31, 2016 | March 22, 2017 |
| Adcirca | Tadalafil | Pulmonary arterial hypertension | Complete | February 5, 2010 | July 15, 2010 |
| Adderall XR | Mixed amphetamine salts | Attention deficit hyperactivity disorder | Complete | April 13, 2004 | November 24, 2004 |
| Adderall XR | Mixed amphetamine salts | Attention deficit hyperactivity disorder | Complete | November 29, 2007 | June 25, 2008 |
| Adderall XR | Mixed amphetamine salts | Attention deficit hyperactivity disorder | Withdrawn | December 15, 2004 | |
| Adempas | Riociguat | Pulmonary hypertension, chronic thromboembolic | Complete | September 30, 2013 | July 17, 2014 |
| Adempas | Riociguat | Hypertension artérielle pulmonaire (groupe 1 OMS) | Complete | June 25, 2015 | December 17, 2015 |
| Adlyxine | lixisénatide | Diabète sucré de type 2 | Complete | May 29, 2017 | November 23, 2017 |
| Admelog | Insuline lispro | Diabète sucré, type 1 et 2 | Cancelled | ||
| Advicor | Niacin/lovastatin | Hypercholesterolemia and mixed dyslipidemia | Complete | October 18, 2005 | April 26, 2006 |
| Aermony RespiClick | propionate de fluticasone | L’asthme | Complete | October 4, 2017 | December 19, 2018 |
| Zenhale (inhalation aerosol) | Mometasone furoate and formoterol | Asthma maintenance (adults, children 12 or older) | Complete | February 16, 2011 | September 28, 2011 |
| Afinitor | Évérolimus | astrocytoma sous-épendymaire à cellules géantes associé à la sclérose tubéreuse de Bourneville | Complete | March 19, 2014 | April 15, 2015 |
| Afinitor | Everolimus | renal angiomyolipoma associated with tuberous sclerosis complex (TSC) | Complete | March 8, 2013 | September 25, 2013 |
| Aimovig | érénumab | Migraine | Active | May 2, 2019 | |
| Akynzeo | nétupitant / palonosétron | la prévention des nausées et vomissements associés à la chimiothérapie | Complete | December 8, 2017 | June 20, 2018 |
| Aldurazyme | Laronidase | Mucopolysarccharidosis 1 (MPS 1), Hurler, Hurler-Scheie, Scheie | Complete | February 3, 2005 | July 14, 2005 |
| Aloxi (injection) | Palonosetron hydrochloride | Nausea and vomiting (chemotherapy induced) prevention | Complete | October 5, 2012 | May 15, 2013 |
| Aloxi (capsule) | Palonosetron hydrochloride | Nausea and vomiting (chemotherapy induced) prevention | Complete | October 5, 2012 | April 24, 2013 |
| Aloxi (capsule) | Palonosetron | palonosétron Indication: Prévention des nausées et vomissements induits par la chimiothérapie | Withdrawn | February 6, 2015 | |
| Altace Plus Felodipine | Ramipril/felodipine extended release | Hypertension | Complete | June 22, 2006 | November 15, 2006 |
| Altace HCT | Ramipril/hydrochlorothiazide | Hypertension | Cancelled | October 26, 2006 | |
| Altace HCT | Ramipril/hydrochlorothiazide | Hypertension | Complete | March 26, 2007 | June 14, 2007 |
| Alvesco | Ciclesonide | asthma | Complete | July 24, 2006 | December 20, 2006 |
| Amevive | Alefacept | Psoriasis, moderate to severe chronic plaque | Complete | February 28, 2006 | September 27, 2006 |
| Amevive | Alefacept | Psoriasis, moderate to severe chronic plaque | Complete | November 16, 2004 | May 26, 2005 |
| Anoro Ellipta | Uméclidinium et vilantérol | Maladie pulmonaire obstructive chronique | Complete | February 26, 2014 | January 15, 2015 |
| Apidra | Insulin glulisine | Diabetes, Mellitus (Type 1 & 2) | Complete | August 29, 2008 | February 19, 2009 |
| Apprilon | Doxycycline monohydrate | Rosacea treatment | Complete | April 27, 2012 | March 27, 2013 |
| Aptiom | Acétate d'eslicarbazépine | Épilepsie, crises partielles | Complete | August 15, 2014 | April 16, 2015 |
| Aptivus | Tipranavir | HIV infection | Complete | December 15, 2005 | May 17, 2006 |
| Arbesda RespiClick | propionate de fluticasone / xinafoate de salmétérol | L’asthme | Complete | October 4, 2017 | December 19, 2018 |
| Arnuity Ellipta | Furoate de fluticasone | Asthme | Complete | June 26, 2015 | December 17, 2015 |
| ASMANEX | Mometasone furoate | Asthma, (Bronchial) Prophylactic management of steroid responsive | Complete | November 10, 2011 | May 16, 2012 |
| Atripla | Efavirenz, emtricitabine, tenofovir disoproxil fumarate | HIV | Complete | October 30, 2007 | April 17, 2008 |
| Aubagio | Teriflunomide | Multiple Sclerosis, relapsing | Complete | August 28, 2013 | June 18, 2014 |
| Somatuline Autogel | Lanreotide acetate | Acromegaly | Complete | February 20, 2007 | July 19, 2007 |
| Avodart | Dutasteride | Prostatic hyperplasia, benign | Complete | August 24, 2004 | January 20, 2005 |
| Axert | Almotriptan | Migraine | Complete | December 24, 2003 | May 27, 2004 |
| Azarga | Brinzolamide and timolol maleate suspension | Glaucoma and ocular hypertension | Complete | August 28, 2009 | February 18, 2010 |
| Azilect | Rasagiline mesylate | Parkinson’s disease | Complete | March 10, 2009 | |
| Azilect | Rasagiline mesylate | Parkinson's disease | Complete | September 1, 2006 | March 28, 2007 |
| Banzel | Rufinamide | Lennox-Gastaut syndrome; adjunctive treatment of seizures | Complete | September 20, 2011 | March 15, 2012 |
| Baraclude | Entecavir | Hepatitis B (chronic) | Complete | December 12, 2006 | November 28, 2007 |
| Basaglar | Insuline glargine | diabète de type 1 ou 2 | Active | October 5, 2015 | April 14, 2016 |
| Benlysta | Bélimumab | lupus érythémateux systémique | Suspended | May 29, 2019 | |
| Benlysta | Belimumab | Systemic lupus erythematosus | Complete | September 19, 2011 | April 25, 2012 |
| Biktarvy | bictégravir/emtricitabine/ténofovir/alafénamide | Infection au VIH-1 | Complete | April 30, 2018 | October 25, 2018 |
| Inflectra (Produit biologique ultérieur) | Infliximab | Maladie de Crohn et colite ulcéreuse | Complete | April 12, 2016 | October 25, 2016 |
| Botox | OnabotulinumtoxinA | Migraine, chronic | Complete | August 15, 2013 | May 28, 2014 |
| Botox | OnabotulinumtoxinA | Urinary incontinence | Complete | November 25, 2013 | November 12, 2014 |
| Botox | OnabotulinumtoxinA | Neurogenic Detrusor Overactivity | Complete | January 31, 2012 | July 19, 2012 |
| Botox | onabotulinumtoxinA | migraine chronique | Active | November 2, 2018 | |
| Ultibro Breezhaler | Indacatérol/glycopyrronium | MPOC | Complete | February 3, 2014 | December 19, 2014 |
| Brenzys | Étanercept | Polyarthrite rhumatoïde, spondylarthrite ankylosante | Complete | April 20, 2016 | October 25, 2016 |
| Breo Ellipta | furoate de fluticasone et vilantérol | Asthme | Withdrawn | May 2, 2018 | |
| Breo Ellipta | Fluticasone furoate /vilanterol | Chronic Obstructive Pulmonary Disease (COPD) | Active | October 29, 2013 | August 18, 2014 |
| Breo Ellipta | Furoate de fluticasone et vilantérol (sous forme de trifénatate) | Asthme | Complete | August 10, 2015 | February 18, 2016 |
| Breo Ellipta | fluticasone furoate/vilantérol | MPOC | Withdrawn | June 28, 2017 | |
| Brilinta | Ticagrelor | Thrombotic events in Acute Coronary Syndromes, Prevention | Complete | June 1, 2011 | December 16, 2011 |
| Brilinta | Ticagrelor | Acute Coronary Syndromes (ACS) | Cancelled | June 8, 2010 | |
| Brilinta | ticagrélor | Prévention des événements athérothrombotiques avec antécédents d’infarctus du myocarde | Complete | February 18, 2016 | August 25, 2016 |
| Brineura | cerliponase alpha | Lipofuscinoses ceroïdes neuronales de type 2 | Complete | July 31, 2018 | May 23, 2019 |
| Brivlera | Brivaracétam | Epilepsie, crises partielles | Complete | April 19, 2016 | |
| BuTrans | Buprenorphine transdermal patch | Pain, persistent (moderate intensity) | Complete | May 9, 2011 | September 28, 2011 |
| BuTrans | Buprenorphine transdermal patch | Pain, persistent (moderate intensity) | Cancelled | October 15, 2010 | |
| Byetta | Exenatide | Diabetes mellitus, Type 2 | Complete | August 23, 2011 | July 19, 2012 |
| Bystolic | Nebivolol | Hypertension, essential | Complete | February 4, 2013 | July 18, 2013 |
| Cablivi | caplacizumab | Purpura thrombocytopénique thrombotique acquis | En attente | ||
| Caduet | Amlodipine besylate/ atorvastatin calcium | Hypertension/ Dyslipidemia | Complete | December 15, 2005 | May 17, 2006 |
| Campral | Acamprosate calcium | Alcohol Abstinence | Complete | July 22, 2008 | |
| Campral | Acamprosate calcium | Alcohol Abstinence | Complete | August 29, 2007 | March 27, 2008 |
| Cayston | Aztreonam for inhalation solution | Cystic fibrosis (CF) with chronic pulmonary pseudomonas aeruginosa infections | Complete | December 2, 2010 | July 18, 2011 |
| Celsentri | Maraviroc | HIV | Withdrawn | November 2, 2007 | |
| Celsentri | Maraviroc | HIV | Complete | May 7, 2008 | November 12, 2008 |
| Celsentri | Maraviroc | HIV-1, treatment naïve (adult) | Complete | December 8, 2010 | July 18, 2011 |
| Cerdelga | Éliglustat | Maladie de Gaucher | Complete | January 20, 2017 | July 26, 2017 |
| Champix | Varenicline tartrate | Smoking-cessation | Complete | March 21, 2007 | August 16, 2007 |
| Cimzia | Certolizumab pegol | Arthritis, rheumatoid | Complete | September 3, 2009 | May 27, 2010 |
| Cimzia | certolizumab pégol | Psoriasis en plaques, de modéré à grave | Active | May 13, 2019 | |
| Cimzia | Certolizumab pegol | Arthritis, psoriatic | Complete | September 2, 2014 | April 17, 2015 |
| Cimzia | Certolizumab pegol | spondylarthrite ankylosante | Complete | June 23, 2014 | April 17, 2015 |
| Cinqair | reslizumab | L'asthme éosinophile | Complete | October 24, 2018 | March 27, 2019 |
| Cinqair | Reslizumab | Asthme à éosinophiles | Complete | August 4, 2016 | March 22, 2017 |
| Cipralex | Escitalopram oxalate | Depression, Major Depressive Disorder (MDD) | Complete | June 8, 2006 | January 24, 2007 |
| Cipralex | Escitalopram oxalate | Depression, Major Depressive Disorder (MDD) | Withdrawn | August 3, 2005 | |
| Ciprodex | Ciprofloxacin hydrochloride and dexamethasone otic suspension | Otitis media with otorrhea & otitis externa, acute | Complete | June 11, 2004 | January 26, 2005 |
| Ciprodex | Ciprofloxacin hydrochloride & dexamethasone otic suspension | Otitis media with otorrhea & otitis externa, acute | Complete | June 15, 2007 | October 18, 2007 |
| Combigan Ophthalmic Solution | Brimonidine tartrate/timolol maleate | Glaucoma | Complete | December 15, 2003 | May 27, 2004 |
| COMPLERA | Emtricitabine/ rilpivirine/ tenofovir disoproxil fumarate | HIV-1 infection in antiretroviral treatment- naïve adults | Complete | October 19, 2011 | April 19, 2012 |
| Constella | Linaclotide | Syndrome du colon irritable avec constipation | Complete | December 17, 2014 | September 23, 2015 |
| Contrave | Chlorhydrate de naltrexone et chlorhydrate de bupropion | Suspended | May 1, 2019 | ||
| Copaxone | Glatiramer acetate | Clinically Isolated Syndrome (CIS), suggestive of Multiple Sclerosis | Complete | April 29, 2009 | November 25, 2009 |
| Cortiment | Budesonide | Colite ulcéreuse | Complete | May 24, 2016 | March 22, 2017 |
| Cosentyx | Secukinumab | Arthrite psoriasique | Complete | February 19, 2016 | August 23, 2016 |
| Cosentyx | Secukinumab | Psoriasis, moderate to severe plaque | Complete | December 8, 2014 | October 28, 2015 |
| Cosentyx | Secukinumab | Spondylarthrite ankylosante | Complete | February 19, 2016 | August 23, 2016 |
| Nucynta CR | Tapentadol | Pain, moderate to moderately severe | Complete | February 1, 2011 | September 28, 2011 |
| Cresemba | Isavuconazole | Traitement de l'aspergillose et de la mucormycose invasives | Complete | November 2, 2018 | May 15, 2019 |
| Crysvita | Burosumab | Traitement de l’hypophosphatémie liée à l’X | Active | July 23, 2019 | |
| Cubicin | Daptomycin | Skin and skin structure infections & bacteremia | Complete | March 6, 2008 | September 24, 2008 |
| Cuvposa | Glycopyrrolate | Sialorrhée chronique grave, neurologique | Active | May 31, 2019 | |
| Cymbalta | Duloxetine hydrochloride | Pain, Neuropathic, Diabetic | Complete | February 8, 2008 | August 14, 2008 |
| Cymbalta | Duloxetine hydrochloride | Depressive, Major Disorder (MDD) | Complete | February 8, 2008 | August 14, 2008 |
| Cystadrops | Cystéamine | Dépôts cornéens de cristaux de cystine | Complete | December 10, 2018 | June 18, 2019 |
| Daklinza | Daclatasvir | Hépatite C chronique | Complete | February 13, 2015 | September 21, 2015 |
| Daklinza | daclatasvir | Hépatite C, chronique | Complete | January 6, 2016 | May 19, 2016 |
| Daxas | Roflumilast | Chronic obstructive pulmonary disease (COPD) | Complete | November 30, 2010 | July 27, 2011 |
| Delstrigo | doravirine, lamuvidine et fumarate de ténofovir disoproxil | infection due au VIH-1 | Complete | November 16, 2018 | May 14, 2019 |
| Denavir | Penciclovir | Herpes labialis (cold sores) | Complete | September 20, 2006 | April 26, 2007 |
| Descovy | Emtricitabine /ténofovir alafénamide | Infection par le VIH-1 | Complete | January 29, 2016 | August 24, 2016 |
| Diacomit | Stiripentol | Dravet Syndrome | Complete | October 30, 2013 | October 16, 2014 |
| Dificid | Fidaxomicin | Clostridium difficile infection | Complete | July 10, 2012 | December 19, 2012 |
| Duaklir Genuair | Aclidinium bromide/formoterol fumarate dihydrate | Chronic Obstructive Pulmonary Disease (COPD) | Complete | April 1, 2015 | September 18, 2015 |
| Duodopa | Levodopa / carbidopa | Parkinson's disease | Complete | December 19, 2008 | July 22, 2009 |
| Duodopa | lévodopa/carbidopa (demande de régimes d'assurance médicaments) | la maladie de Parkinson | Complete | February 8, 2018 | August 22, 2018 |
| DuoTrav | Travoprost and timolol maleate | Glaucoma | Complete | March 24, 2006 | August 24, 2006 |
| Dupixent | dupilumab | dermatite atopique | Complete | October 27, 2017 | June 27, 2018 |
| Dymista | Azelastine HCl and fluticasone propionate | Seasonal allergic rhinitis | Active | December 9, 2014 | June 17, 2015 |
| Dysport Therapeutic | abobotulinumtoxinA | Dystonie cervicale | Complete | January 31, 2017 | July 26, 2017 |
| Dysport Therapeutic | abobotulinumtoxinA | spasticité des membres inférieurs | Complete | February 7, 2018 | August 21, 2018 |
| Dysport Therapeutic | abobotulinumtoxinA | Spasticité des membres supérieurs | Complete | April 24, 2017 | October 24, 2017 |
| Ebixa | Memantine hydrochloride | Dementia (Alzheimer type), moderate to severe | Complete | December 21, 2004 | November 23, 2005 |
| Edarbi | Azilsartan medoxomil | Hypertension, essential | Complete | March 8, 2013 | October 17, 2013 |
| Edarbyclor | Azilsartan medoxomil + chlorthalidone | Hypertension, essential | Complete | March 8, 2013 | October 17, 2013 |
| Edurant | Rilpivirine | HIV (treatment - naive adult) | Complete | July 29, 2011 | February 15, 2012 |
| Effient | Prasugrel | Acute Coronary Syndrome (ACS) | Complete | December 12, 2011 | June 14, 2012 |
| Effient | Prasugrel hydrochloride | Acute Coronary Syndrome (ACS) | Complete | May 5, 2010 | February 16, 2011 |
| Egrifta | Tésamoréline | Lipodystrophie associée à l’infection par le VIH | Complete | March 2, 2016 | August 24, 2016 |
| Elaprase | Idursulfase | Mucopolysarccharidosis II (MPS II), Hunter Syndrome | Complete | July 13, 2007 | December 19, 2007 |
| Elelyso | Taliglucérase alfa | Maladie de Gaucher | Complete | August 15, 2014 | October 28, 2015 |
| Eliquis | Apixaban | Thromboembolic events, (venous) prevention | Complete | December 20, 2011 | June 14, 2012 |
| Eliquis | Apixaban | Thromboembolic events prevention, (atrial fibrillation) | Complete | September 25, 2012 | March 20, 2013 |
| Eliquis | Apixaban | traitement et prévention de la récurrence de l’incident thromboembolique veineux | Complete | September 18, 2014 | May 7, 2015 |
| Trelegy Ellipta | furoate de fluticasone uméclidinium vilantérol | maladie pulmonaire obstructive chronique (MPOC) | Complete | March 1, 2018 | August 23, 2018 |
| Incruse Ellipta | Umeclidinium | maladie pulmonaire obstructive chronique (MPOC) | Complete | March 4, 2015 | September 18, 2015 |
| Emend | Aprepitant | Nausea and Vomiting, Chemotherapy induced | Complete | August 29, 2007 | February 20, 2008 |
| Restasis ophthalmic emulsion | Cyclosporine | Dry eye disease, Moderate to moderately severe | Complete | December 17, 2010 | July 18, 2011 |
| Enablex | Darifenacin hydrobromide | Bladder, overactive | Complete | April 26, 2006 | October 19, 2006 |
| Enablex | Darifenacin hydrobromide | Bladder, overactive | Complete | October 1, 2008 | April 16, 2009 |
| Entresto | sacubitril/valsartan | insuffisance cardiaque, classe NYHA II or III | Complete | September 18, 2015 | March 18, 2016 |
| Entyvio | Vedolizumab | Colite ulcéreuse | Complete | February 20, 2015 | October 28, 2015 |
| Entyvio | Védolizumab | Maladie de Chrohn | Complete | April 27, 2016 | October 27, 2016 |
| Epclusa | Sofosbuvir/ velpatasvir | Hepatitis C, chronic | Complete | April 22, 2016 | October 26, 2016 |
| Erelzi | étanercept | Spondylarthrite ankylosante, polyarthrite juvénile idiopathique, polyarthrite rhumatoïde | Complete | February 2, 2017 | July 25, 2017 |
| Esbriet | Pirfenidone | Pulmonary fibrosis (idiopathic, mild to moderate) | Complete | August 29, 2014 | April 15, 2015 |
| Esbriet | Pirfenidone | Pulmonary fibrosis (idiopathic, mild to moderate) | Complete | October 5, 2012 | April 18, 2013 |
| Eucrisa | crisaborole | dermatite atopique | Complete | May 25, 2018 | March 27, 2019 |
| Evra | Norgelestromin/ethinyl estradiol | Contraceptive, patch | Complete | December 19, 2003 | June 23, 2004 |
| Exelon Patch | Rivastigmine | Dementia (Alzheimer's type) | Complete | December 21, 2007 | July 23, 2008 |
| Exjade | Deferasirox | Iron overload | Complete | October 26, 2006 | April 19, 2007 |
| Eylea | Aflibercept | Dégénérescence maculaire liée à l'âge | Complete | November 18, 2013 | October 20, 2014 |
| Eylea | Aflibercept | Œdème maculaire secondaire à une occlusion veineuse rétinienne | Complete | December 14, 2015 | July 27, 2016 |
| Eylea | Aflibercept | œdème maculaire diabétique | Complete | September 16, 2014 | May 7, 2015 |
| Eylea | Aflibercept | œdème maculaire secondaire à une occlusion de la veine centrale de la rétine | Complete | October 17, 2014 | May 7, 2015 |
| Fabrazyme | Agalsidase beta | Fabry Disease | Complete | December 10, 2004 | May 18, 2005 |
| Fabrazyme | Agalsidase beta | Fabry Disease | Complete | February 24, 2004 | November 24, 2004 |
| Fampyra | Fampridine | Multiple Sclerosis, improve walking disability | Withdrawn | November 6, 2014 | |
| Fampyra | Fampridine | Multiple Sclerosis, improve walking disability | Complete | April 16, 2012 | November 28, 2012 |
| Fasenra | benralizumab | Asthme grave, éosinophile | Complete | October 24, 2018 | March 27, 2019 |
| Fasenra | benralizumab | Asthme grave, éosinophile | Complete | February 23, 2018 | August 23, 2018 |
| Fentora | Fentanyl buccal | Accès douloureux transitoires, adultes cancéreux | Complete | July 12, 2016 | February 21, 2017 |
| Ferriprox | Défériprone | Surcharge en fer transfusionnelle | Complete | September 24, 2015 | March 18, 2016 |
| Fibristal | Ulipristal acetate | Uterine fibroids (signs and symptoms) | Complete | April 17, 2013 | November 15, 2013 |
| Fibristal | acétate d’ulipristal | le traitement des fibromes utérins (signes et symptômes) | Complete | June 21, 2017 | November 22, 2017 |
| Fibristal | Acétate d'ulipristal | Fibromes utérins (signes et symptômes) | Complete | March 28, 2019 | July 24, 2019 |
| Finacea | Azelaic acid | Rosacea | Complete | August 31, 2010 | February 16, 2011 |
| Firazyr | Icatibant | angioedème héréditaire | Complete | March 4, 2014 | December 19, 2014 |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis | Withdrawn | December 18, 2008 | |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis (in women), Severe | Complete | October 23, 2009 | March 17, 2010 |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis, glucocorticoid induced | Complete | December 18, 2008 | July 22, 2009 |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis | Withdrawn | May 29, 2006 | |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis | Complete | June 8, 2004 | December 22, 2004 |
| Forteo | Teriparatide (rDNA origin) injection | Osteoporosis | Withdrawn | June 12, 2009 | |
| Forxiga | Dapagliflozin | Diabète sucré (Type 2) | Complete | April 30, 2015 | November 20, 2015 |
| Forxiga | dapagliflozine | diabète de type 2 | Complete | September 4, 2015 | April 27, 2016 |
| Fosavance | Alendronate sodium/cholecalciferol | Osteoporosis | Complete | March 27, 2006 | September 27, 2006 |
| Fosrenol | Lanthanum carbonate hydrate | Hyperphosphatemia, end-stage renal disease | Complete | June 28, 2007 | January 30, 2008 |
| Fulphila | pegfilgrastim | Neutropénie fébrile associée à un cancer non myéloïde | Complete | November 14, 2018 | |
| Fycompa | Pérampanel | Épilepsie, crise tonico-clonique généralisée | Complete | November 24, 2015 | May 18, 2016 |
| Fycompa | Perampanel | Epilepsy, partial onset seizures | Complete | March 8, 2013 | October 17, 2013 |
| Galafold | migalastat | Maladie de Fabry | Complete | June 9, 2017 | January 24, 2018 |
| Galexos | Simeprevir | Hepatitis C, chronic | Complete | August 22, 2013 | June 18, 2014 |
| Gelnique | Oxybutynin Chloride Gel | Bladder, overactive | Complete | October 25, 2011 | May 24, 2012 |
| Genotropin | Somatropin | Turner Syndrome | Complete | May 27, 2013 | December 20, 2013 |
| Genotropin | Somatropin | Growth hormone deficiency, adult | Complete | May 27, 2013 | December 20, 2013 |
| Genotropin | Somatropin | Growth hormone deficiency, pediatric | Complete | May 27, 2013 | December 20, 2013 |
| Tudorza Genuair | Aclidinium bromide | Chronic Obstructive Pulmonary Disease (COPD) | Complete | August 21, 2013 | April 21, 2014 |
| Genvoya | Elvitégravir/cobicistat/emtricitabine/ténofovir alafénamide | Infection au VIH | Complete | September 24, 2015 | March 18, 2016 |
| Gilenya | Fingolimod | Multiple Sclerosis | Complete | May 10, 2011 | November 16, 2011 |
| Glatect | Acétate de glatiramer | Sclérose en plaques cyclique | Complete | January 20, 2017 | July 25, 2017 |
| Grastek | Phleum pratense | Allergy (grass) | Complete | September 30, 2013 | September 24, 2014 |
| Grastofil | Filgrastim | Prévention ou traitement de la neutropénie sous diverses indications | Complete | September 11, 2015 | March 18, 2016 |
| Harvoni | Ledipasvir / sofosbuvir | hépatite C chronique | Complete | September 15, 2014 | March 18, 2015 |
| Harvoni | lédipasvir, sofosbuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 18, 2016 |
| Hemangiol | Propranolol | Infantile hemangioma | Withdrawn | December 23, 2014 | |
| Hemangiol | Solution orale de propranolol | Hémangiome infantile | Complete | August 25, 2016 | February 21, 2017 |
| Hepsera | Adefovir dipivoxil | Hepatitis B | Complete | June 29, 2007 | October 18, 2007 |
| Hepsera | Adefovir dipivoxil | Hepatitis B | Complete | April 24, 2006 | November 29, 2006 |
| Holkira Pak | ombitasvir/paritaprévir/ritonavir et dasabuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 26, 2016 |
| Holkira Pak | Ombitasvir/paritaprévir/ritonavir and dasabuvir | Hépathite C chronique | Complete | December 3, 2014 | June 18, 2015 |
| Humira | Adalimumab | Hidrosadénite suppurée | Complete | November 3, 2015 | May 19, 2016 |
| Humira | Adalimumab | Crohn's disease | Complete | July 12, 2007 | December 19, 2007 |
| Humira | Adalimumab | Ankylosing spondylitis (AS) | Complete | November 17, 2006 | June 27, 2007 |
| Humira | Adalimumab | Arthritis, Rheumatoid | Complete | September 24, 2004 | February 11, 2005 |
| Humira | Adalimumab | Arthritis, Juvenile Idiopathic | Complete | February 4, 2013 | July 18, 2013 |
| Humira | Adalimumab | Psoriasis | Complete | April 15, 2008 | October 16, 2008 |
| Humira | Adalimumab | Arthritis, Psoriatic | Complete | June 21, 2006 | November 29, 2006 |
| Humira | Adalimumab | Colite ulcéreuse | Complete | September 25, 2015 | April 15, 2016 |
| Humira | Adalimumab | Ulcerative colitis | Withdrawn | December 23, 2013 | |
| Simponi I.V. | Golimumab | Arthritis, Rheumatoid | Complete | September 12, 2013 | July 17, 2014 |
| Ikervis | cyclosporine | Kératite sévère | Withdrawn | May 15, 2017 | |
| Ilaris | Canakinumab | Cryopyrin-Associated Periodic Syndrome (CAPS) | Complete | July 7, 2010 | January 26, 2011 |
| Ilaris | Canakinumab | Arthrite idiopathique juvénile systémique | Complete | December 23, 2015 | June 17, 2016 |
| Ilumya | Tildrakizumab | Psoriasis en plaque, modéré à grave | Received | July 15, 2019 | |
| Iluvien | implant intravitréen d'acétonide de fluocinolone | œdème maculaire diabétique | Active | April 3, 2019 | |
| Iluvien | fluocinolone acétonide | œdème maculaire diabétique | Withdrawn | December 21, 2017 | |
| Imbruvica | ibrutinib | Réaction chronique du greffon contre l’hôte | NotFiled | ||
| Incivek | Telaprevir | Hepatitis C infection (genotype 1), Chronic | Complete | August 23, 2011 | February 15, 2012 |
| Incivek | Telaprevir | Complete | December 21, 2012 | June 13, 2013 | |
| Incivek | Telaprevir | Hepatitis C infection, chronic | Complete | February 19, 2013 | June 13, 2013 |
| Inflectra | Infliximab | Ankylosing spondylitis, plaque psoriasis, psoriatic arthritis, rheumatoid arthritis | Complete | June 17, 2014 | December 19, 2014 |
| Inspiolto Respimat | Tiotropium / olodatérol | Maladie pulmonaire obstructive chronique (MPOC) (COPD) | Complete | June 4, 2015 | December 17, 2015 |
| Inspra | Eplerenone | Post myocardial infarction | Complete | May 6, 2009 | November 25, 2009 |
| Inspra | Eplerenone | Heart failure, NYHA class II | Complete | July 12, 2013 | April 24, 2014 |
| Intelence | Etravirine | HIV | Complete | April 2, 2008 | August 14, 2008 |
| Intuniv XR | Guanfacine hydrochloride | Attention deficit hyperactivity disorder (ADHD) | Complete | August 27, 2013 | September 24, 2014 |
| Invega | Paliperidone | Schizophrenia | Complete | November 1, 2007 | May 28, 2008 |
| Invega Sustenna | Paliperidone palmitate | Schizophrenia | Complete | July 9, 2010 | April 25, 2011 |
| Invokamet | Canagliflozine et metformine | Diabète de type 2 | Complete | March 3, 2016 | August 25, 2016 |
| Invokana | Canagliflozin | Diabetes mellitus, type 2 | Withdrawn | June 5, 2013 | |
| Invokana | Canagliflozine | Diabète de type 2 | Complete | February 24, 2014 | January 15, 2015 |
| Iressa | Gefitinib | Cancer, Lung , non-small cell | Complete | December 22, 2003 | June 23, 2004 |
| Isentress | Raltegravir | HIV | Complete | November 29, 2007 | May 14, 2008 |
| Isentress | Raltegravir | HIV (treatment naïve) | Complete | December 4, 2009 | June 23, 2010 |
| Izba | solution ophtalmique travoprost | Glaucoma à angle ouvert | Complete | March 1, 2017 | October 25, 2017 |
| Janumet | Sitagliptin phosphate monohydrate / metformin hydrochloride | Diabetes mellitus (Type 2) | Complete | November 4, 2009 | June 23, 2010 |
| Januvia | Sitagliptin phosphate | Diabetes mellitus (Type 2) | Complete | October 29, 2009 | June 23, 2010 |
| Januvia | Sitagliptin phosphate | Diabetes mellitus (Type 2) | Complete | December 20, 2007 | June 18, 2008 |
| Jardiance | Empagliflozin | Diabète sucré type 2 à haut risque cardiovasculaire | Complete | April 27, 2016 | October 26, 2016 |
| Jardiance | Empagliflozine | Diabète sucré de type 2 | Complete | April 23, 2015 | October 15, 2015 |
| Jentadueto | Linagliptin-metformin | Diabetes mellitus (Type 2) | Complete | March 8, 2013 | October 17, 2013 |
| Jetrea | Ocriplasmin | Vitreomacular adhesion | Complete | June 6, 2013 | December 20, 2013 |
| Jinarc | Tolvaptan | polykystose rénale à caractère autosomique dominant (ADPKD) | Complete | May 29, 2015 | February 24, 2016 |
| Jublia | éfinaconazole | Onychomycose | Complete | August 2, 2018 | May 23, 2019 |
| Juluca | Dolutégravir rilpivirine | Infection par le VIH | Complete | December 21, 2017 | June 20, 2018 |
| Jurnista | Hydromorphone hydrochloride | Pain, Chronic (moderate to severe) | Complete | December 4, 2009 | May 19, 2010 |
| Juxtapid | Lomitapide | hypercholestérolémie familiale | Complete | July 8, 2014 | April 17, 2015 |
| Kalydeco | Ivacaftor | Cystic Fibrosis, R117H CFTR gating mutation | Complete | May 8, 2015 | November 19, 2015 |
| Kalydeco | Ivacaftor | Cystic Fibrosis patients (G551D mutation) | Complete | September 27, 2012 | March 22, 2013 |
| Kalydeco | Ivacaftor | Fibrose cystique (mutations de CFTR) | Complete | May 1, 2014 | December 19, 2014 |
| Kanuma | sebelipase alfa | Déficit en lipase acide lysosomique | Complete | November 2, 2017 | September 26, 2018 |
| Kazano | Alogliptine alliée à metformine | diabète de type 2 | Complete | January 30, 2014 | January 15, 2015 |
| Kevzara | sarilumab | Polyarthrite rhumatoïde | Complete | October 12, 2016 | April 18, 2017 |
| Kivexa | Abacavir/lamivudine | HIV infection | Complete | July 26, 2005 | December 7, 2005 |
| Komboglyze | Saxagliptin + metformin | Diabetes Mellitus, Type 2 | Complete | August 23, 2013 | June 20, 2014 |
| Komboglyze | Saxagliptin + metformin | Diabetes Mellitus, Type 2 | Withdrawn | June 6, 2013 | |
| Kuvan | Sapropterin dihydrochloride | Phenylketonuria (PKU). | Complete | July 8, 2010 | January 26, 2011 |
| Kuvan | Sapropterin dihydrochloride | Phénylcénoturie (PcU) | Complete | February 1, 2016 | October 26, 2016 |
| Kuvan | Sapropterin dihydrochloride | Phenylketonuria (PKU). | Complete | June 1, 2011 | |
| Kynmobi | chlorhydrate d'apomorphine | Maladie de Parkinson | Withdrawn | February 25, 2019 | |
| Lancora | Ivabradine | Insuffisance cardiaque, classes NYHA II à III | Complete | November 8, 2016 | May 24, 2017 |
| Lantus | Insulin glargine (rDNA origin) | Diabetes mellitus, Type 1 & 2 | Complete | February 11, 2005 | September 28, 2005 |
| Lantus | Insulin glargine (rDNA origin) | Diabetes mellitus, Type 1 & 2 | Complete | March 27, 2006 | October 25, 2006 |
| Lantus | Insulin glargine (rDNA origin) | Diabetes mellitus, Type 1 & 2 | Complete | June 9, 2009 | |
| Lapelga | Pegfilgrastim | Neutropénie fébrile | Complete | February 23, 2018 | |
| Latuda | Lurasidone | schizophrenia | Complete | July 3, 2012 | January 23, 2013 |
| Latuda | Lurasidone | Schizophrenia | Complete | May 9, 2013 | December 20, 2013 |
| Lemtrada | Alemtuzumab | Multiple Sclerosis, relapsing | Withdrawn | October 1, 2013 | |
| Lemtrada | Alemtuzumab | sclérose en plaques cyclique | Complete | November 27, 2014 | June 18, 2015 |
| Levemir | Insulin detemir | Diabetes mellitus | Withdrawn | February 2, 2009 | |
| Levemir | Insulin detemir | Diabetes mellitus | Complete | March 10, 2009 | August 20, 2009 |
| Levemir | Insulin detemir | Diabetes mellitus | Complete | December 19, 2005 | August 2, 2006 |
| Levemir | Insulin detemir | Diabetes mellitus Type1, Pediatrics | Complete | March 10, 2009 | August 20, 2009 |
| Lixiana NVAF | Edoxaban | Fibrillation auriculaire non valvulaire, prévention des accidents vasculaires cérébraux et des embolies systémiques | Complete | September 9, 2016 | March 21, 2017 |
| Lixiana VTE | Edoxaban | Thromboembolie veineuse, traitement et prevention de récurrence | Complete | September 9, 2016 | May 25, 2017 |
| Lodalis | Colesevelam hydrochloride | Hypercholesterolemia | Complete | April 27, 2012 | December 19, 2012 |
| Lokelma | Cyclosilicate de zirconium sodique | Hyperkaliémie chez les adultes | Active | May 17, 2019 | |
| Lotemax | Loteprednol etabonate | Post-operative inflammation following cataract surgery | Complete | December 2, 2009 | May 19, 2010 |
| Lucentis | Ranibizumab injection | Macular edema, secondary to retinal vein occlusion | Complete | April 25, 2012 | October 18, 2012 |
| Lucentis | Ranibizumab | Macular degeneration, age-related | Complete | July 12, 2007 | March 27, 2008 |
| Lucentis | Ranibizumab | néovascularisation choroïdienne due à la myopie | Complete | February 28, 2014 | February 19, 2015 |
| Lucentis | Ranibizumab | Macular edema, diabetic | Complete | September 14, 2011 | March 19, 2012 |
| Lyrica | Pregabalin | Pain, Neuropathic | Complete | June 27, 2005 | January 25, 2006 |
| Lyrica | Pregabalin | diabetic peripheral neuropathy | Complete | March 20, 2009 | September 23, 2009 |
| Pantoloc M | Pantoprazole magnesium | Gastric acid secretion, reduction of | Complete | March 17, 2006 | July 20, 2006 |
| Macugen | Pegaptanib sodium | Macular degeneration, age-related | Complete | October 20, 2005 | May 25, 2006 |
| Mavenclad | cladribine | Sclérose en plaques cyclique | Complete | December 1, 2017 | October 24, 2018 |
| Maviret | glécaprévir pibrentasvir | Hépatite C chronique | Complete | June 9, 2017 | January 23, 2018 |
| MDK-Nitisinone | nitisinone | la tyrosinémie héréditaire de type 1 | Complete | September 29, 2017 | April 25, 2018 |
| Mictoryl | chlorhydrate de propivérine | Vessie hyperactive | Complete | October 14, 2016 | April 19, 2017 |
| Mifegymiso | Mifépristone et misoprostol | Interruption médicale de grossesse | Complete | October 7, 2016 | April 18, 2017 |
| Mifégymiso | Mifépristone et misoprostol | Interruption médicale de la grossesse (âge gestationnel jusqu’éa 49 jours) | Withdrawn | February 12, 2016 | |
| mirabégron | Myrbetriq | Vessie hyperactive | Complete | November 27, 2013 | November 12, 2014 |
| Monoferric | Fer-isomaltoside 1000 | Anémie ferriprive | Active | June 26, 2019 | |
| Monoprost | latanoprost | glaucome et hypertension oculaire | Complete | October 25, 2017 | April 24, 2018 |
| Movapo | chlorhydrate d’apomorphine | Maladie de Parkinson | Complete | July 6, 2017 | January 23, 2018 |
| Mozobil | Plerixafor | Hematopoietic stem cell mobilizer in non-Hodgkin's lymphoma and multiple myeloma | Complete | January 24, 2012 | September 26, 2012 |
| Multaq | Dronedarone hydrochloride | Atrial fibrillation | Complete | September 18, 2009 | May 27, 2010 |
| Myfortic | Mycophenolate sodium | Organ rejection in allogeneic renal transplants, Prophylaxis | Complete | March 3, 2005 | July 8, 2005 |
| Myozyme | Alglucosidase | Pompe’s disease | Complete | October 10, 2006 | June 14, 2007 |
| Myrbetriq | Mirabegron | Bladder, Overactive | Withdrawn | March 8, 2013 | |
| Naglazyme | Galsulfase (Drug Plan Submission) | mucopolysaccharidose de type VI | Complete | August 20, 2015 | February 19, 2016 |
| Nesina | Alogliptine | diabète de type 2 | Complete | January 30, 2014 | January 15, 2015 |
| Neulasta | Pegfilgrastim | Neutropenia | Complete | March 29, 2004 | October 27, 2004 |
| Neupro | Rotigotine | Parkinson’s Disease | Complete | July 31, 2013 | May 28, 2014 |
| Neupro | Rotigotine | Maladie de Parkinson | Complete | May 21, 2015 | November 19, 2015 |
| Nexavar | Sorafenib tablets | Cancer, Renal cell carcinoma | Complete | July 31, 2006 | February 28, 2007 |
| Nitisinone | Nitisinone | Tyrosinémie de type 1 | Complete | January 25, 2018 | August 23, 2018 |
| Norprolac | Quinagolide hydrochloride | Hyperprolactinemia | Complete | December 16, 2004 | September 28, 2005 |
| Norprolac | Quinagolide hydrochloride | Hyperprolactinemia | Complete | November 23, 2005 | May 17, 2006 |
| Nplate | Romiplostim | Chronic immune (idiopathic) thrombocytopenic purpura (ITP) | Complete | September 29, 2009 | May 27, 2010 |
| Nucala | mépolizumab | L'asthme éosinophile grave | Complete | October 24, 2018 | March 27, 2019 |
| Nucala | Mépolizumab | Asthme, grave à éosinophiles | Complete | December 18, 2015 | June 16, 2016 |
| Nucynta | chlorhydrate de tapentadol | douleur intense | Complete | April 17, 2018 | October 23, 2018 |
| NuvaRing | Etonogestrel/ethinyl estradiol | Contraceptive, ring | Complete | May 5, 2006 | November 29, 2006 |
| Ocaliva | Acide obéticholique | Cholangite biliaire primitive | Complete | December 22, 2016 | July 25, 2017 |
| Ocrevus | ocrélizumab | Forme progressive primaire de sclérose en plaques | Complete | October 26, 2017 | April 26, 2018 |
| Ocrevus | ocrélizumab | sclérose en plaques cyclique | Complete | May 16, 2017 | November 21, 2017 |
| Odefsey | emtricitabine/rilpivirine/ tenofovir alafenamide | Infection VIH-1 | Complete | November 24, 2016 | May 25, 2017 |
| Ofev | Nintedanib | Idiopathic pulmonary fibrosis (IPF) | Complete | April 23, 2015 | October 15, 2015 |
| Olmetec Plus | Olmesartan medoxomil + hydrochlorothiazide | Hypertension | Complete | November 28, 2008 | May 27, 2009 |
| Olmetec | Olmesartan medoxomil | Hypertension | Complete | November 28, 2008 | May 27, 2009 |
| Olumiant | baricitinib | Polyarthrite rhumatoïde | Active | December 20, 2018 | August 2, 2019 |
| Omnaris | Ciclesonide nasal spray | Allergic Rhinitis (seasonal and perennial) | Complete | May 7, 2008 | November 12, 2008 |
| Omnitrope | Somatropin (rDNA origin) | Growth hormone deficiency in children and adults | Complete | June 12, 2009 | |
| Onbrez | Indacaterol | Chronic Obstructive Pulmonary Disease (COPD), maintenance bronchodilator treatment | Complete | February 29, 2012 | August 16, 2012 |
| Onglyza | Saxagliptin | Diabetes mellitus (Type 2) | Complete | November 9, 2009 | June 17, 2010 |
| Onglyza | Saxagliptin | Diabetes mellitus (Type 2) | Complete | May 9, 2013 | November 15, 2013 |
| Onglyza | Saxagliptin | Diabetes mellitus (Type 2) | Withdrawn | May 28, 2012 | |
| Onpattro | patisiran | La polyneuropathie dans l’amylose de la transthyrétine héréditaire | Active | January 25, 2019 | July 25, 2019 |
| Onsolis | Fentanyl Citrate | Pain (breakthrough), cancer (adults) | Withdrawn | May 10, 2011 | |
| Onsolis | Fentanyl Citrate | Pain (breakthrough), cancer (adults) | Complete | August 22, 2011 | February 15, 2012 |
| Onstryv | safinamide | Maladie de Parkinson | Active | May 29, 2019 | |
| Opsumit | Macitentan | Pulmonary arterial hypertension | Complete | December 18, 2015 | January 28, 2015 |
| Oralair | Grass Pollen Allergen Extract | Allergic rhinitis (grass pollen) | Complete | September 21, 2012 | March 20, 2013 |
| Orencia | Abatacept | Arthritis, Juvenile Idiopathic & Juvenile Rheumatoid | Complete | August 29, 2008 | April 22, 2009 |
| Orencia | Abatacept | Arthritis, Rheumatoid | Complete | November 29, 2012 | July 18, 2013 |
| Orencia | Abatacept | Arthritis, Rheumatoid | Complete | December 2, 2009 | June 17, 2010 |
| Orencia | Abatacept | Arthritis, Rheumatoid | Complete | October 26, 2006 | June 27, 2007 |
| Orfadin | nitisinone | la tyrosinémie héréditaire de type 1 | Complete | August 29, 2017 | February 21, 2018 |
| Orkambi | lumacaftor/ivacaftor | Fibrose kystique, mutation CFTR F508del | Complete | January 28, 2016 | October 26, 2016 |
| Orkambi | lumacaftor/ivacaftor | Fibrose kystique, mutation F.508del chez les patients âgés de 6 ans et plus | Complete | February 22, 2018 | September 26, 2018 |
| Otezla | Apremilast | Arthrite, psoriatique | Complete | June 8, 2015 | December 17, 2015 |
| Otezla | Apremilast | Psoriasis, en plaques modérées à sévères | Complete | October 8, 2014 | July 22, 2015 |
| Otezla | Aprémilast | Psoriasis, modéré à sévère | Complete | March 3, 2016 | October 26, 2016 |
| Ozanex | ozénoxacine | Impétigo | Complete | January 25, 2018 | October 24, 2018 |
| Ozempic | Sémaglutide | Diabète de type 2 | Complete | November 23, 2018 | May 15, 2019 |
| Ozurdex | dexaméthasone | Œdème maculaire diabétique | Complete | September 26, 2017 | October 24, 2018 |
| Ozurdex | Dexamethasone intravitreal implant | Macular edema following central retinal vein occlusion | Complete | September 1, 2011 | April 25, 2012 |
| Pegasys RBV | Peginterferon alfa-2a and Ribavirin | Hepatitis C, chronic | Complete | May 14, 2004 | October 14, 2004 |
| Pheburane | Phénylbutyrate de sodium | Urea cycle disorders | Complete | October 20, 2015 | |
| Picato | Ingenol mebutate | Keratosis, actinic | Complete | May 9, 2013 | January 22, 2014 |
| Picato | Mébutate d'ingénol | Kératose actinique | Complete | May 26, 2014 | |
| Pifeltro | doravirine | infection due au VIH-1 | Complete | November 16, 2018 | May 14, 2019 |
| Plegridy | Peginterféron béta-1a | Sclérose en plaques cyclique | Complete | June 26, 2015 | December 17, 2015 |
| Teveten Plus | Eprosartan mesylate/ hydrochlorothiazide | Hypertension, Essential | Complete | July 8, 2004 | December 15, 2004 |
| Pradaxa | Dabigatran etexilate | Thromboembolism (venous), prevention | Complete | July 8, 2008 | January 28, 2009 |
| Pradaxa | Dabigatran etexilate | Atrial fibrillation prevention of stroke and systemic embolism | Cancelled | May 31, 2010 | |
| Pradaxa | Dabigatran etexilate | Atrial fibrillation prevention of stroke and systemic embolism | Complete | October 28, 2010 | June 22, 2011 |
| Pradaxa | Dabigatran etexilate | Atrial fibrillation prevention of stroke and systemic embolism | Complete | March 18, 2013 | July 18, 2013 |
| Praluent | Alirocumab | Hypercholestérolémie primaire (non-familiale et hétérozygote familiale), dyslipidémie mixte | Complete | January 12, 2016 | July 20, 2016 |
| Praxbind | Idarucizumab (Drug Plan Submission) | neutralisation de l’effet anticoagulant du dabigatran | Withdrawn | May 30, 2016 | |
| Prevymis | létermovir | Infection au cytomégalovirus, prophylaxie | Complete | December 7, 2017 | June 20, 2018 |
| Prexige | Lumiracoxib | Osteoarthritis (Knee) | Complete | December 15, 2006 | July 25, 2007 |
| Prezcobix | Darunavir/cobicistat | Infection par le VIH | Complete | May 22, 2014 | March 18, 2015 |
| Prezista | Darunavir | HIV infection | Complete | August 29, 2006 | February 14, 2007 |
| Prezista | Darunavir | HIV infection (Pediatric) | Complete | December 22, 2009 | June 17, 2010 |
| Prezista | Darunavir | HIV (treatment naive) | Complete | March 27, 2009 | October 14, 2009 |
| Pristiq | Desvenlafaxine succinate | Depressive, Major Disorder (MDD) | Complete | March 5, 2009 | September 23, 2009 |
| Probuphine | chlorhydrate de buprénorphine | le traitement de la dépendance aux opioïdes | Complete | December 21, 2017 | August 22, 2018 |
| Procysbi | bitartrate de cystéamine | cystinose néphropathique | Complete | August 8, 2017 | January 24, 2018 |
| Prolia | Denosumab (Déposé par un régime d’assurance médicaments) | Ostéoporose chez les hommes | Complete | March 10, 2015 | September 21, 2015 |
| Prolia | Denosumab | Osteoporosis, postmenopausal women | Complete | August 26, 2010 | March 30, 2011 |
| Prolia | Dénosumab | Ostéoporose, femmes postménopausiques | Complete | October 26, 2015 | May 20, 2016 |
| Quinsair | Lévofloxacine | Fibrose kystique compliquée par des infections pulmonaires chroniques dues à Pseudomas æruginosa | Complete | May 31, 2016 | November 21, 2016 |
| Radicava | édavarone | sclérose latérale amyotrophique | Complete | July 5, 2018 | March 27, 2019 |
| Ralivia | Tramadol hydrochloride | Pain | Complete | October 29, 2007 | June 25, 2008 |
| RAPAFLO | Silodosin | Prostatic Hyperplasia, benign | Complete | October 25, 2011 | April 19, 2012 |
| Raptiva | Efalizumab | Psoriasis, moderate to severe chronic plaque | Complete | June 19, 2007 | |
| Raptiva | Efalizumab | Psoriasis, moderate to severe chronic plaque | Complete | October 25, 2005 | August 24, 2006 |
| Rasilez | Aliskiren | Hypertension | Complete | November 30, 2007 | June 25, 2008 |
| Ravicti | phénylbutyrate de glycérol | Troubles du cycle de l’urée | Complete | August 30, 2016 | March 21, 2017 |
| Rebif | Interferon beta-1a | Clinically Isolated Syndrome | Complete | March 8, 2013 | August 15, 2013 |
| Relistor | Methylnaltrexone bromide | Constipation, Opioid-induced | Complete | May 7, 2008 | January 28, 2009 |
| Relpax | Eletriptan hydrobromide | Migraine | Complete | September 21, 2004 | March 23, 2005 |
| Remicade | Infliximab | Ulcerative Colitis | Complete | September 29, 2008 | April 22, 2009 |
| Remodulin | Treprostinil sodium | Pulmonary arterial hypertension (NYHA Class III and IV patients) | Complete | February 24, 2006 | July 20, 2006 |
| Remodulin | Treprostinil sodium | Pulmonary arterial hypertension (NYHA Class III and IV patients) | Complete | July 14, 2004 | November 17, 2004 |
| Remsima | Infliximab | Spondylarthrite ankylosante, psoriasis en plaques, arthrite psoriasique, arthrite rhumatoïde | Withdrawn | May 30, 2014 | |
| Renflexis | infliximab | arthrite rhumatoïde, spondylarthrite ankylosante, maladie de Crohn chez l’adulte, maladie de Crohn pédiatrique, maladie de Crohn fistuleuse, colite ulcéreuse chez l’adulte, colite ulcéreuse pédiatrique, arthrite psoriasique, psoriasis en plaques | Complete | September 5, 2017 | February 20, 2018 |
| Repatha | Evolocumab | hyperlipidémie primaire et dyslipidémie mixte | Complete | February 17, 2017 | November 22, 2017 |
| Repatha | Évolocumab | Hyperlipédémie primaire, dyslipédémie mixte, hypercholestérolémie familiale homozygote | Complete | June 30, 2015 | February 19, 2016 |
| Replagal | Agalsidase alfa | Fabry Disease | Complete | February 19, 2004 | November 24, 2004 |
| Resotran | Prucalopride | Constipation, chronic | Complete | January 30, 2012 | July 19, 2012 |
| Spiriva Respimat | Tiotropium bromide | Chronic Obstructive Pulmonary Disease (COPD) | Complete | December 23, 2014 | July 16, 2015 |
| Revatio | Sildenafil citrate | Pulmonary arterial hypertension (WHO class II and III) | Complete | September 20, 2006 | February 14, 2007 |
| Revestive | téduglutide | Syndrome de l’intestin court (SIC) | Complete | November 26, 2015 | July 27, 2016 |
| Revestive | Téduglutide | Syndrome du grêle court (SGC), pédiatrique | Active | May 29, 2019 | |
| Revolade | Eltrombopag | Thrombocytopénie associée à l’hépatite C | Complete | March 31, 2014 | March 18, 2015 |
| Revolade | Eltrombopag olamine | Thrombocytopenic purpura chronic immune (idiopathic) | Complete | April 26, 2011 | October 24, 2011 |
| Revolade | eltrombopag | Anémie aplastique grave | NotFiled | ||
| Rexulti | Brexpiprazole | Schizophrénie | Complete | February 3, 2017 | November 22, 2017 |
| Reyataz | Atazanavir | HIV infection | Complete | December 16, 2003 | May 27, 2004 |
| Rituxan | Rituximab | Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA), remission induction (adults) | Complete | February 24, 2012 | August 16, 2012 |
| Rituxan | Rituximab | Arthritis, Rheumatoid | Complete | June 26, 2006 | February 14, 2007 |
| Rosiver | Ivermectine | Rosacée | Complete | April 30, 2015 | November 19, 2015 |
| Samsca | Tolvaptan | Hyponatremia, non-hypovolemic | Complete | July 3, 2012 | February 13, 2013 |
| Saphris | Asenapine | Schizophrenia | Complete | December 12, 2011 | June 14, 2012 |
| Saphris | Asenapine | Bipolar I disorder | Complete | December 12, 2011 | June 14, 2012 |
| Sativex | Delta-9-tetrahydrocannabinol/cannabidiol | Pain, cancer (adjunctive analgesia to maximum tolerated strong opioids) | Complete | August 7, 2007 | February 20, 2008 |
| Sativex | Delta-9-tetrahydrocannabinol/cannabidiol | Pain, Neuropathic (adjunctive) in MS. | Complete | February 27, 2007 | September 26, 2007 |
| Sebivo | Telbivudine | Hepatitis B (chronic) | Complete | December 4, 2006 | September 26, 2007 |
| Seebri | Glycopyrronium bromide | Chronic Obstructive Pulmonary Disease (COPD), maintenance bronchodilator treatment | Complete | November 30, 2012 | May 15, 2013 |
| Segluromet | ertugliflozine et chlorhydrate de metformine | Diabète de type 2 | Complete | April 30, 2018 | January 23, 2019 |
| Semglee | Insuline glargine | Diabète sucré, type 1 et 2 | Withdrawn | November 14, 2018 | |
| Sensipar | Cinacalcet hydrochloride | Secondary hyper-parathyroidism in chronic kidney disease | Complete | August 20, 2004 | March 23, 2005 |
| Signifor | Pasiréotide diaspartate | maladie de Cushing | Complete | February 27, 2014 | February 24, 2015 |
| Siliq | Brodalumab | Psoriasis en plaques, modéré ou grave | Complete | December 14, 2017 | June 20, 2018 |
| Silkis | Calcitriol | Psoriasis, mild to moderate plaque | Complete | March 15, 2010 | September 22, 2010 |
| Simbrinza | Brinzolamide / brimonidine | Glaucoma and ocular hypertension | Complete | November 3, 2014 | June 17, 2015 |
| Simponi | Golimumab | Arthritis, Rheumatoid | Complete | September 3, 2009 | March 17, 2010 |
| Simponi | Golimumab | Ankylosing spondylitis | Complete | September 3, 2009 | March 17, 2010 |
| Simponi | Golimumab | Ulcerative colitis | Complete | July 12, 2013 | March 19, 2014 |
| Simponi | Golimumab | Arthritis, psoriatic | Complete | September 3, 2009 | March 17, 2010 |
| Sivextro | Tedizolid phosphate | Acute bacterial skin and skin structure infections | Withdrawn | January 16, 2015 | |
| Skyrizi | risankizumab | Le psoriasis en plaques modéré à grave | Complete | October 22, 2018 | May 28, 2019 |
| Soliqua | lixisénatide et insuline glargine | Diabète de type 2 | Complete | May 18, 2018 | December 24, 2018 |
| Soliris | Eculizumab | Hemolytic Uremic Syndrome, Atypical | Complete | January 7, 2013 | July 18, 2013 |
| Soliris | Eculizumab | Paroxysmal nocturnal hemoglobinuria (PNH) | Complete | September 18, 2009 | February 18, 2010 |
| Soliris | éculizumab | myasthénie grave généralisée | En attente | ||
| Soliris | Éculizumab | syndrome hémolytique et urémique, atypique | Complete | February 9, 2015 | |
| Somavert | Pegvisomant | acromegaly | Complete | January 25, 2006 | August 2, 2006 |
| Sovaldi | sofosbuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 18, 2016 |
| Sovaldi | Sofosbuvir | Hepatitis C, chronic | Complete | October 1, 2013 | August 18, 2014 |
| Spinraza | nusinersen | amyotrophie spinale | Complete | June 28, 2017 | December 22, 2017 |
| Spinraza | Nusinersen | Amyotrophie spinale | Complete | July 24, 2018 | February 27, 2019 |
| Spriafil | Posaconazole | Aspergillus and Candida infections | Complete | May 24, 2007 | January 30, 2008 |
| Stalevo | Carbidopa, levodopa and entacapone | Parkinsons Disease | Complete | April 15, 2008 | October 16, 2008 |
| Steglatro | Diabète de type 2 | Complete | April 30, 2018 | January 23, 2019 | |
| Stelara | Ustekinumab | Psoriasis | Complete | January 7, 2009 | June 17, 2009 |
| Stelara | ustekinumab | Maladie de Crohn | Complete | September 12, 2016 | March 21, 2017 |
| Stelara | ustékinumab | Colite ulcéreuse | Received | August 12, 2019 | |
| Stelara | Ustekinumab | Arthritis, Psoriatic | Complete | October 30, 2013 | October 20, 2014 |
| Strattera | Atomoxetine hydrochloride | Attention deficit hyperactivity disorder | Complete | September 25, 2006 | |
| Strattera | Atomoxetine hydrochloride | Attention deficit hyperactivity disorder | Complete | January 25, 2005 | September 28, 2005 |
| Strensiq | Asfotase alfa | Hypophosphatasie, Durant l’enfance | Complete | August 21, 2015 | March 23, 2016 |
| Stribild | Elvitegravir/ Cobicistat/ Emtricitabine/ Tenofovir Disoproxil Fumarate | HIV-1 infection | Complete | November 30, 2012 | May 15, 2013 |
| Sublinox | Zolpidem tartrate | Insomnia, short-term treatment | Complete | March 7, 2013 | September 25, 2013 |
| Sublocade | Buprénorphine | Traitement du trouble de consommation d'opioïdes | Complete | December 20, 2018 | June 19, 2019 |
| Suboxone | Buprenorphine/naloxone | Opioid drug dependence (Substitution treatment) | Complete | March 6, 2008 | September 24, 2008 |
| Sunvepra | Asunaprévir | Hépatite C chronique | Complete | February 13, 2015 | July 20, 2016 |
| Sutent | Sunitinib | Gastrointestinal stromal tumour (GIST) | Complete | July 20, 2006 | March 28, 2007 |
| Sutent | Sunitinib malate | Cancer, Metastatic renal cell carcinoma | Complete | September 20, 2006 | April 26, 2007 |
| Symdeko | tézacaftor/ivacaftor | Fibrose kystique, mutation(s) F508del | NotFiled | ||
| Symtuza | Darunavir/cobicistat/emtricitabine/ténofovir alafénamide | infection par le VIH-1 | Complete | December 22, 2017 | July 25, 2018 |
| Synjardy | Empagliflozine et metformine | Diabète de type 2 | Complete | April 29, 2016 | October 25, 2016 |
| Takhzyro | lanadélumab | Angio-œdème héréditaire, prévention | Active | May 29, 2019 | |
| Taltz | ixékizumab | Spondylarthrite ankylosante | En attente | ||
| Taltz | Ixekizumab | Psoriasis en plaques modéré à sévère | Complete | March 23, 2016 | October 25, 2016 |
| Taltz | ixékizumab | Arthrite psoriasique évolutive | Complete | February 20, 2018 | August 21, 2018 |
| Tarceva | Erlotinib | Cancer, Lung , non-small cell | Complete | July 19, 2005 | December 7, 2005 |
| Targin | Oxycodone HCI / naloxone HCI | Pain, Moderate to severe and relief of opioid-induced constipation | Complete | July 5, 2011 | January 25, 2012 |
| Targin | Oxycodone / naloxone | Pain, Moderate to severe and relief of opioid-induced constipation | Cancelled | November 30, 2010 | |
| TBC | propionate d’halobétasol et tazarotène | Psoriasis en plaques de modéré à grave | Withdrawn | February 4, 2019 | |
| TBC | glucagon | Réactions hypoglycémiques graves | Active | July 24, 2019 | |
| TBC | cabotégravir-rilpivirine | Infection par VIH-1 | Received | August 19, 2019 | |
| TBC | filgrastim | Prévention ou le traitement de la neutropénie dans différentes indications | Cancelled | November 1, 2018 | |
| TBC | Tafamidis | Amyloïdose à transthyrétine | Active | July 4, 2019 | |
| TBC | Chlorhydrate d'eskétamine | Trouble dépressif majeur chez les adultes | Suspended | June 24, 2019 | |
| TBC | Darunavir / cobicistat | infection par le VIH | Withdrawn | April 4, 2014 | |
| TBC | dolutégravir/lamivudine | Infection par le VIH-1 | Active | February 21, 2019 | |
| TBC | cabotégravir sodium | Infection par VIH-1 | Received | August 19, 2019 | |
| TBC | Ravulizumab | Hémoglobinurie paroxystique nocturne | Suspended | July 4, 2019 | |
| TBC | filgrastim | Neutropénie, mobilisation des cellules sanguines (différentes indications) | Cancelled | ||
| TBC | Active | July 4, 2019 | |||
| TBC | etonogestrel | Prévention de la grossesse | En attente | ||
| Tecfidera | Dimethyl fumarate | Multiple Sclerosis, relapsing | Complete | February 4, 2013 | September 25, 2013 |
| Technivie | ombitasvir/ paritaprévir/ ritonavir | hépatite C chronique, VHC de génotype 4 | Complete | September 4, 2015 | March 18, 2016 |
| Tegsedi | inotersen | amylose héréditaire liée à la transthyrétine | Active | February 22, 2019 | |
| Telzir | Fosamprenavir calcium | HIV infection | Complete | January 24, 2005 | June 16, 2005 |
| Thelin | Sitaxsentan sodium | Pulmonary arterial hypertension (WHO class II and III) | Complete | May 5, 2008 | January 28, 2009 |
| Thelin | Sitaxsentan sodium | Pulmonary arterial hypertension (WHO class II and III) | Complete | June 22, 2007 | January 30, 2008 |
| Tivicay | Dolutegravir | HIV infection | Complete | October 18, 2013 | August 18, 2014 |
| Toctino | Alitretinoin | Eczema | Complete | May 6, 2011 | October 24, 2011 |
| Toviaz | Fesoterodine fumarate | Bladder, overactive | Complete | April 27, 2012 | October 18, 2012 |
| Trajenta | Linagliptin | Diabetes mellitus, Type 2 | Complete | August 23, 2011 | February 15, 2012 |
| Tramacet | Tramadol hydrochloride /acetaminophen | Acute pain | Complete | October 2, 2006 | May 17, 2007 |
| Translarna | ataluren | La dystrophinopathie | En attente | ||
| Trelstar | Triptorelin pamoate | Cancer, prostate | Complete | February 27, 2006 | July 20, 2006 |
| Tremfya | Psoriasis en plaques de modéré à sévère | Complete | August 25, 2017 | February 21, 2018 | |
| Tresiba | insuline dégludec | Diabète sucré, types 1 et 2 | Complete | May 31, 2017 | November 20, 2017 |
| Tridural | Tramadol hydrochloride | Pain | Complete | November 29, 2007 | April 17, 2008 |
| Trintellix | bromhydrate de vortioxétine | trouble dépressif majeur (TDM) chez les adultes | Active | May 1, 2019 | |
| Trintellix | Vortioxetine | trouble dépressif majeur | Withdrawn | October 31, 2014 | |
| Triumeq | Dolutegravir / abacavir / lamivudine | HIV Infection | Complete | July 31, 2014 | April 17, 2015 |
| Trosec | Trospium chloride | Bladder, overactive | Complete | March 24, 2006 | August 24, 2006 |
| Trulicity | dulaglutide | Diabète sucré, type 2 | Complete | December 22, 2015 | June 16, 2016 |
| Truvada | Emtricitabine/tenofovir disoproxil fumarate | HIV infection | Complete | July 7, 2008 | December 17, 2008 |
| Truvada | Emtricitabine/tenofovir disoproxil fumarate | HIV infection | Complete | May 29, 2006 | October 25, 2006 |
| Truvada | Emtricitabine/fumarate de ténofovir disoproxil | Infection par le VIH, prophylaxie préexposition | Complete | March 3, 2016 | August 24, 2016 |
| Twynsta | Telmisartan / Amlodipine | Essential hypertension | Cancelled | July 9, 2010 | |
| Twynsta | Telmisartan/ Amlodipine | Hypertension, Essential | Complete | August 23, 2011 | December 16, 2011 |
| Tysabri | Natalizumab | Multiple Sclerosis, relapsing-remitting | Complete | May 6, 2008 | February 25, 2009 |
| Tysabri | Natalizumab | Multiple Sclerosis, relapsing-remitting | Complete | October 26, 2006 | April 26, 2007 |
| Uloric | Febuxostat | Gout | Complete | October 27, 2010 | April 25, 2011 |
| Uptravi | Sélexipag | Hypertension artérielle pulmonaire (OMS) de classe II et III | Complete | March 31, 2016 | October 28, 2016 |
| Vantas | Histrelin acetate | Cancer, prostate | Complete | September 20, 2006 | April 26, 2007 |
| Vascepa | Icosapent éthyle | Évènements ischémiques chez les patients traités aux statines | Suspended | June 17, 2019 | |
| Velphoro | oxyhydroxyde sucro-ferrique | hyperphosphatémie, insuffisance rénale terminale | Complete | June 12, 2018 | January 2, 2019 |
| Vemlidy | ténofovir alafénamide | Hépatite B chronique | Complete | September 28, 2017 | March 26, 2018 |
| Verkazia | Cyclosporine | Kératoconjonctivite vernale grave, pédiatrique (≥4 ans) | Active | May 22, 2019 | |
| Vesicare | Solifenacin succinate | Bladder, overactive | Complete | July 24, 2006 | January 24, 2007 |
| Vesicare | Solifenacin succinate | Bladder, overactive | Complete | January 5, 2009 | June 17, 2009 |
| VesiFlow | Succinate de solifénacine / chlorhydrate de tamsulosine | hyperplasie bénigne de la prostate (HBP)-associée à des symptômes des voies urinaires inférieures | Withdrawn | April 6, 2015 | |
| VFEND | Voriconazole | Candidemia | Complete | March 24, 2006 | October 25, 2006 |
| VFEND | Voriconazole | Aspergillosis, Invasive | Complete | October 25, 2004 | April 14, 2005 |
| VFEND | Voriconazole | Aspergillosis, Invasive | Withdrawn | August 24, 2004 | |
| Viacoram | perindopril arginine / bésylate d’amlodipine | Hypertension essentielle | Complete | May 2, 2016 | October 26, 2016 |
| Viberzi | éluxadoline | Syndrome du côlon irritable avec diarrhée | Complete | February 23, 2018 | August 24, 2018 |
| Victoza | Liraglutide | Diabetes mellitus, Type 2 | Complete | November 29, 2010 | September 28, 2011 |
| Victoza | Liraglutide | Diabète, Type 2 | Withdrawn | October 20, 2016 | |
| Victrelis | Boceprevir | Hepatitis C, chronic | Complete | May 3, 2011 | October 24, 2011 |
| Victrelis | Boceprevir | Complete | December 21, 2012 | June 13, 2013 | |
| Victrelis | Boceprevir | Hepatitis C infection, chronic | Complete | February 19, 2013 | June 13, 2013 |
| Viibryd | vilazodone | Dépression, trouble dépressif caractérisé | NotFiled | ||
| Vimizim | élosulfase alfa | Mucopolysaccharidose IVA (syndrome de Morquio) | Complete | August 5, 2014 | March 25, 2015 |
| Vimizim | Élosulfase alfa | Mucopolysaccharidose IVA (Syndrome de Morquio A) | Complete | November 10, 2015 | May 20, 2016 |
| Vimpat | Lacosamide | Epilepsy, partial onset seizures (POS) | Complete | October 25, 2010 | April 25, 2011 |
| Viread | Tenofovir disoproxil fumarate | HIV infection | Complete | August 11, 2005 | March 15, 2006 |
| Viread | Tenofovir disoproxil fumarate | HIV infection | Complete | February 23, 2004 | August 25, 2004 |
| Viread | Tenofovir disoproxil fumarate | Hepatitis B (chronic) | Complete | October 2, 2008 | March 18, 2009 |
| Viread | Tenofovir disoproxil fumarate | HIV infection | Complete | July 7, 2008 | |
| Visanne | Dienogest | Pelvic pain associated with endometriosis | Complete | October 18, 2011 | April 19, 2012 |
| Volibris | Ambrisentan | Pulmonary arterial hypertension (WHO class II and III) | Complete | July 9, 2008 | December 17, 2008 |
| Vosevi | sofosbuvir/velpatasvir/voxilaprévir | Hépatite C chronique | Complete | July 28, 2017 | January 23, 2018 |
| VPRIV | Velaglucerase alfa | Gaucher Disease | Complete | October 28, 2010 | April 25, 2011 |
| Vyvanse | Lisdexamfetamine dimesylate | Attention deficit hyperactivity disorder | Complete | July 10, 2009 | December 18, 2009 |
| Vyzulta | latanoprostène bunod | Glaucome à angle ouvert ou hypertension oculaire | Complete | November 23, 2018 | July 24, 2019 |
| Xarelto | Rivaroxaban | Thromboembolic events (venous), pulmonary embolism | Complete | May 6, 2013 | March 26, 2014 |
| Xarelto | Rivaroxaban | Thromboembolism (venous), prevention | Complete | May 7, 2008 | December 17, 2008 |
| Xarelto | Rivaroxaban | Thromboembolism (venous) prevention | Complete | June 24, 2011 | |
| Xarelto | rivaroxaban | Prévention de l’accident vasculaire cérébral et d'évènements cardiovasculaires causés par la coronopathie ou la maladie artérielle périphérique | Complete | May 24, 2018 | November 20, 2018 |
| Xarelto | Rivaroxaban | Deep-Vein Thrombosis (treatment), without Symptomatic Pulmonary Embolism | Complete | February 27, 2012 | August 16, 2012 |
| Xarelto | Rivaroxaban | Atrial fibrillation, stroke prevention | Complete | October 21, 2011 | April 19, 2012 |
| Xarelto | Rivaroxaban | Deep-Vein Thrombosis (treatment), without Symptomatic Pulmonary Embolism | Complete | October 10, 2012 | |
| Xarelto | Rivaroxaban | stroke prevention in patients with atrial fibrillation. | Complete | March 18, 2013 | July 18, 2013 |
| Xeljanz | Tofacitinib | Arthrite rhumatoïde | Complete | May 5, 2014 | April 17, 2015 |
| Xeljanz | Tofacitinib | Polyarthrite psoriasique | En attente | ||
| Xeljanz | tofacitinib | Complete | June 27, 2018 | February 27, 2019 | |
| Xeomin | Clostridium botulinum neurotoxin type A, free from complexing proteins | Blepharospasm | Complete | June 12, 2009 | December 16, 2009 |
| Xeomin | Clostridium botulinum neurotoxin type A, free from complexing proteins | Cervical Dystonia | Complete | June 12, 2009 | December 16, 2009 |
| Xeomin | Clostridium botulinum neurotoxin type A, free from complexing proteins | Spasticity, Post-stroke | Complete | June 12, 2009 | December 16, 2009 |
| Xermelo | télotristat | syndrome carcinoïde | Complete | September 27, 2018 | June 26, 2019 |
| Xgeva | Denosumab (Drug Plan Submission) | Prévention des complications squelettiques causées par des métastases osseuses découlant du cancer du sein | Complete | July 31, 2015 | February 25, 2016 |
| Xgeva | Denosumab (Drug Plan Submission) | Prevention of skeletal-related events due to bone metastases from other solid tumors (excluding breast and prostate cancer), including non-small cell lung cancer | Complete | July 31, 2015 | March 23, 2016 |
| XGEVA | Denosumab | Prevention of skeletal-related events due to bone metastases from solid tumours | Complete | June 6, 2011 | November 16, 2011 |
| Xiaflex | Collagenase clostridium histolyticum | Dupuytren’s contracture with a palpable cord | Complete | August 30, 2012 | March 27, 2013 |
| XigDuo | dapagliflozin/metformin hydrochloride | Diabète sucré de type 2 | Active | January 7, 2016 | July 20, 2016 |
| Zytram XL | Tramadol hydrochloride | Pain, acute | Withdrawn | November 3, 2006 | |
| Zytram XL | Tramadol hydrochloride | Pain, acute | Complete | March 15, 2007 | September 26, 2007 |
| Xolair | Omalizumab | Asthma, severe persistent | Cancelled | April 18, 2005 | |
| Xolair | Omalizumab | Asthma, severe persistent | Complete | October 13, 2005 | March 7, 2006 |
| Xolair | Omalizumab (Déposé par un régime d’assurance médicaments) | Asthme grave persistent | Complete | November 18, 2015 | May 18, 2016 |
| Xolair | Omalizumab | Urticaire, idiopathique chronique | Complete | September 22, 2014 | May 7, 2015 |
| Xultophy | insuline dégludec et liraglutide | Diabète sucré de type 2 | Active | January 30, 2019 | |
| Xyrem | Sodium oxybate | Narcolepsy | Complete | July 9, 2008 | January 28, 2009 |
| Xyrem | Sodium oxybate | Narcolepsy | Withdrawn | August 29, 2007 | |
| Yasmin | Drospirenone /ethinyl estradiol | Contraceptive, oral | Complete | January 20, 2005 | June 16, 2005 |
| Zavesca | Miglustat | Gaucher disease | Complete | May 13, 2004 | November 24, 2004 |
| Zaxine | Rifaximine | Encéphalopathie, Hépatique | Complete | August 5, 2014 | April 16, 2015 |
| Zeldox | Ziprasidone hydrochloride | Schizophrenia and related psychotic disorders | Complete | January 10, 2008 | August 14, 2008 |
| Zenhale | Mometasone/formoterol | Asthma maintenance (adults, children 12 or older) | Complete | June 6, 2012 | December 19, 2012 |
| Zepatier | Elbasvir / Grazoprévir | Hépatite C chronique | Complete | October 27, 2015 | May 19, 2016 |
| Zinbryta | Daclizumab bêta | Sclérose en plaques cyclique | Complete | December 20, 2016 | June 20, 2017 |