| Marque de commerce | Nom générique | Indication | État d'avancement du projet | Présentation reçue | Date d'émission de la recommandation |
|---|---|---|---|---|---|
| Gynazole.1 | Nitrate de butoconazole | Infection vaginale | Complete | June 30, 2004 | January 26, 2005 |
| NovoMix 30 | Insuline asparte et protamine d'insuline asparte | Diabète sucré | Complete | October 13, 2005 | April 26, 2006 |
| Fosavance 70/5600 | Alendronate monosodique et cholécalciférol | Ostéoporose | Complete | December 18, 2008 | June 17, 2009 |
| Abilify | Aripiprazole | Schizophrénie | Complete | November 6, 2009 | April 27, 2010 |
| Abilify | Aripiprazole | Dépression, trouble dépressif majeur (TDM) | Complete | October 1, 2013 | October 22, 2014 |
| Abilify Maintena | Aripirazole | Schizophrénie | Complete | January 6, 2014 | December 19, 2014 |
| Abilify | Aripiprazole | Schizophrénie et troubles psychotiques connexes | Complete | March 29, 2011 | July 18, 2011 |
| Abstral | Citrate de fentanyl | Douleur, cancer (accès douloureux) | Complete | June 30, 2011 | December 16, 2011 |
| Aclasta | Acide zolédronique | Complete | July 20, 2011 | November 16, 2011 | |
| Aclasta | Acide zolédronique | Ostéoporose, femmes ménopausées | Complete | November 29, 2007 | June 25, 2008 |
| Actemra | Tocilizumab | Arthrite juvénile idiopathique | Complete | January 30, 2012 | July 19, 2012 |
| Actemra | Tocilizumab | Artérite à cellules géantes (ACG) | Complete | September 25, 2017 | March 27, 2018 |
| Actemra | Tocilizumab | polyarthrite rhumatoïde | Complete | March 3, 2014 | February 19, 2015 |
| Actemra | Tocilizumab | Polyarthrite rhumatoïde | Complete | May 27, 2010 | November 17, 2010 |
| Actemra | Tocilizumab | Arthrite juvénile idiopathique polyarticulaire | Complete | July 29, 2013 | March 19, 2014 |
| Actikerall | Fluorouracil et acide salicylique | kératose actinique hyperkératosique | Complete | August 31, 2016 | March 22, 2017 |
| Adcirca | Tadalafil | Hypertension artérielle pulmonaire | Complete | February 5, 2010 | July 15, 2010 |
| Adderall XR | Sels mixtes d’amphétamine | Trouble du déficit de l'attention avec hyperactivité | Complete | April 13, 2004 | November 24, 2004 |
| Adderall XR | Sels mixtes d'amphétamine | Trouble du déficit de l'attention avec hyperactivité | Complete | November 29, 2007 | June 25, 2008 |
| Adderall XR | Sels mixtes d'amphétamine | Trouble du déficit de l'attention avec hyperactivité | Withdrawn | December 15, 2004 | |
| Adempas | Riociguat | Hypertension pulmonaire thromboembolique chronique | Complete | September 30, 2013 | July 17, 2014 |
| Adempas | Riociguat | Hypertension artérielle pulmonaire (groupe 1 OMS) | Complete | June 25, 2015 | December 17, 2015 |
| Adlyxine | lixisénatide | Diabète sucré de type 2 | Complete | May 29, 2017 | November 23, 2017 |
| Admelog | Insuline lispro | Diabète sucré, type 1 et 2 | Cancelled | ||
| Advicor | Niacin/lovastatin | Hypercholestérolémie et dyslipidémie mixte | Complete | October 18, 2005 | April 26, 2006 |
| Aermony RespiClick | propionate de fluticasone | L’asthme | Complete | October 4, 2017 | December 19, 2018 |
| Afinitor | Évérolimus | Astrocytome sous-épendymaire à cellules géantes associé à la sclérose tubéreuse de Bourneville | Complete | March 19, 2014 | April 15, 2015 |
| Afinitor | Évérolimus | Angiomyolipome rénal avec sclérose tubéreuse de Bourneville | Complete | March 8, 2013 | September 25, 2013 |
| Aimovig | érénumab | Migraine | Active | May 2, 2019 | |
| Akynzeo | nétupitant / palonosétron | Prévention des nausées et vomissements associés à la chimiothérapie | Complete | December 8, 2017 | June 20, 2018 |
| Aldurazyme | Laronidase | Mucopolysaccharidose 1, maladie de Hurler, maladie de Hurler-Scheie, maladie de Scheie | Complete | February 3, 2005 | July 14, 2005 |
| Aloxi (injection) | Chlorhydrate de palonosétron | Prévention des nausées et vomissements induits par la chimiothérapie | Complete | October 5, 2012 | May 15, 2013 |
| Aloxi (capsule) | Chlorhydrate de palonosétron | Prévention des nausées et vomissements induits par la chimiothérapie | Complete | October 5, 2012 | April 24, 2013 |
| Aloxi (capsule) | Palonosetron | Prévention des nausées et vomissements induits par la chimiothérapie | Withdrawn | February 6, 2015 | |
| Altace Plus Felodipine | Ramipril/félodipine à libération prolongée | Hypertension | Complete | June 22, 2006 | November 15, 2006 |
| Altace HCT | Ramipril/hydrochlorothiazide | Hypertension | Cancelled | October 26, 2006 | |
| Altace HCT | Ramipril/hydrochlorothiazide | Hypertension | Complete | March 26, 2007 | June 14, 2007 |
| Alvesco | Ciclesonide | Asthme | Complete | July 24, 2006 | December 20, 2006 |
| Amevive | Aléfacept | Psoriasis en plaques de modéré à grave | Complete | February 28, 2006 | September 27, 2006 |
| Amevive | Aléfacept | Psoriasis en plaques de modéré à grave | Complete | November 16, 2004 | May 26, 2005 |
| Anoro Ellipta | Uméclidinium et vilantérol | Maladie pulmonaire obstructive chronique | Complete | February 26, 2014 | January 15, 2015 |
| Apidra | Insuline glulisine | Diabète de type 1 et de type 2 | Complete | August 29, 2008 | February 19, 2009 |
| Apprilon | Doxycycline monohydratée | Rosacée | Complete | April 27, 2012 | March 27, 2013 |
| Aptiom | Acétate d'eslicarbazépine | Épilepsie, crises partielles | Complete | August 15, 2014 | April 16, 2015 |
| Aptivus | Tipranavir | Infection par le VIH | Complete | December 15, 2005 | May 17, 2006 |
| Arbesda RespiClick | Propionate de fluticasone / xinafoate de salmétérol | Asthme | Complete | October 4, 2017 | December 19, 2018 |
| Arnuity Ellipta | Furoate de fluticasone | Asthme | Complete | June 26, 2015 | December 17, 2015 |
| ASMANEX | Furoate de mométasone | Prophylaxie (bronchique) de l'asthme sensible aux stéroïdes | Complete | November 10, 2011 | May 16, 2012 |
| Atripla | Éfavirenz, emtricitabine, fumarate de ténofovir disoproxil | VIH | Complete | October 30, 2007 | April 17, 2008 |
| Aubagio | Teriflunomide | Sclérose en plaques cyclique | Complete | August 28, 2013 | June 18, 2014 |
| Somatuline Autogel | Acétate de lanréotide | Acromégalie | Complete | February 20, 2007 | July 19, 2007 |
| Avodart | Dutastéride | Hyperplasie bénigne de la prostate | Complete | August 24, 2004 | January 20, 2005 |
| Axert | Almotriptan | Migraine | Complete | December 24, 2003 | May 27, 2004 |
| Azarga | Suspension de brinzolamide et de maléate de timolol | Glaucome et hypertension oculaire | Complete | August 28, 2009 | February 18, 2010 |
| Azilect | Mésylate de rasagiline | Maladie de Parkinson | Complete | September 1, 2006 | March 28, 2007 |
| Azilect | Mésylate de rasagiline | Maladie de Parkinson | Complete | March 10, 2009 | |
| Zenhale (aérosol pour inhalation) | Furoate de mométasone et formotérol | Traitement d'entretien de l'asthme (adultes et enfants de 12 ans ou plus) | Complete | February 16, 2011 | September 28, 2011 |
| Banzel | Rufinamide | Syndrome de Lennox-Gastaut; traitement d'appoint des convulsions | Complete | September 20, 2011 | March 15, 2012 |
| Baqsimi | Glucagon | Réactions hypoglycémiques graves | Complete | July 24, 2019 | January 22, 2020 |
| Baraclude | Entécavir | Hépatite B (chronique) | Complete | December 12, 2006 | November 28, 2007 |
| Basaglar | Insuline glargine | diabète de type 1 ou 2 | Active | October 5, 2015 | April 14, 2016 |
| Benlysta | Bélimumab | lupus érythémateux systémique | Active | May 29, 2019 | |
| Benlysta | Bélimumab | Lupus érythémateux disséminé | Complete | September 19, 2011 | April 25, 2012 |
| Beovu | brolucizumab | Dégénérescence maculaire liée à l'âge | Active | September 26, 2019 | |
| Biktarvy | Bictégravir/emtricitabine/ténofovir/alafénamide | Infection au VIH-1 | Complete | April 30, 2018 | October 25, 2018 |
| Inflectra (Produit biologique ultérieur) | Infliximab | Maladie de Crohn et colite ulcéreuse | Complete | April 12, 2016 | October 25, 2016 |
| Botox | Toxine botulinique de type A | Migraines chroniques | Complete | August 15, 2013 | May 28, 2014 |
| Botox | Toxine botulinique de type A | Incontinence urinaire | Complete | November 25, 2013 | November 12, 2014 |
| Botox | Toxine botulinique de type A | Hyperactivité neurogène du détrusor | Complete | January 31, 2012 | July 19, 2012 |
| Botox | onabotulinumtoxinA | Migraine chronique | Complete | November 2, 2018 | October 17, 2019 |
| Ultibro Breezhaler | Indacatérol/glycopyrronium | MPOC | Complete | February 3, 2014 | December 19, 2014 |
| Brenzys | Étanercept | Polyarthrite rhumatoïde, spondylarthrite ankylosante | Complete | April 20, 2016 | October 25, 2016 |
| Breo Ellipta | Furoate de fluticasone et vilantérol | Asthme | Withdrawn | May 2, 2018 | |
| Breo Ellipta | Furoate de fluticasone et vilantérol | Maladie pulmonaire obstructive chronique (MPOC) | Complete | October 29, 2013 | August 18, 2014 |
| Breo Ellipta | Furoate de fluticasone et vilantérol | MPOC | Withdrawn | June 28, 2017 | |
| Breo Ellipta | Furoate de fluticasone et vilantérol (sous forme de trifénatate) | Asthme | Complete | August 10, 2015 | February 18, 2016 |
| Brilinta | ticagrélor | Prévention des événements athérothrombotiques avec antécédents d’infarctus du myocarde | Complete | February 18, 2016 | August 25, 2016 |
| Brilinta | Ticagrélor | Prévention des incidents thrombotiques en contexte de syndrome coronarien aigu | Complete | June 1, 2011 | December 16, 2011 |
| Brilinta | Ticagrélor | Syndrome coronarien aigu (SCA) | Cancelled | June 8, 2010 | |
| Brineura | cerliponase alpha | Lipofuscinoses ceroïdes neuronales de type 2 | Complete | July 31, 2018 | May 23, 2019 |
| Brivlera | Brivaracétam | Epilepsie, crises partielles | Complete | April 19, 2016 | |
| BuTrans | Timbre transdermique de buprénorphine | Douleur persistante (intensité modérée) | Complete | May 9, 2011 | September 28, 2011 |
| BuTrans | Timbre transdermique de buprénorphine | Douleur persistante (intensité modérée) | Cancelled | October 15, 2010 | |
| Byetta | Exénatide | Diabète de type 2 | Complete | August 23, 2011 | July 19, 2012 |
| Bystolic | Nébivolol | Hypertension artérielle essentielle | Complete | February 4, 2013 | July 18, 2013 |
| Vocabria et Cabenuva | cabotégravir sodium cabotégravir-rilpivirine | Infection par VIH-1 | Active | August 19, 2019 | |
| Cablivi | caplacizumab | Purpura thrombocytopénique thrombotique acquis | Active | September 13, 2019 | |
| Caduet | Bésylate d’amlodipine et atorvastatine calcique | Hypertension et dyslipidémie | Complete | December 15, 2005 | May 17, 2006 |
| Campral | Acamprosate calcique | Maintien de l'abstinence d'alcool | Complete | July 22, 2008 | |
| Campral | Acamprosate calcique | Maintien de l'abstinence d'alcool | Complete | August 29, 2007 | March 27, 2008 |
| Cayston | Solution d'aztréonam pour inhalation | Infection pulmonaire chronique à Pseudomonas aeruginosa chez le patient atteint de fibrose kystique | Complete | December 2, 2010 | July 18, 2011 |
| Celsentri | Maraviroc | VIH | Complete | May 7, 2008 | November 12, 2008 |
| Celsentri | Maraviroc | VIH | Withdrawn | November 2, 2007 | |
| Celsentri | Maraviroc | Infection au VIH-2 chez l'adulte jamais encore traité | Complete | December 8, 2010 | July 18, 2011 |
| Cerdelga | Éliglustat | Maladie de Gaucher | Complete | January 20, 2017 | July 26, 2017 |
| Champix | Tartrate de varénicline | Désaccoutumance au tabac | Complete | March 21, 2007 | August 16, 2007 |
| Cimzia | Certolizumab pegol | Polyarthrite rhumatoïde | Complete | September 3, 2009 | May 27, 2010 |
| Cimzia | certolizumab pégol | Psoriasis en plaques, de modéré à grave | Complete | May 13, 2019 | November 20, 2019 |
| Cimzia | Certolizumab pegol | spondylarthrite ankylosante | Complete | June 23, 2014 | April 17, 2015 |
| Cimzia | Certolizumab pegol | Arthrite psoriasique | Complete | September 2, 2014 | April 17, 2015 |
| Cinqair | reslizumab | L'asthme éosinophile | Complete | October 24, 2018 | March 27, 2019 |
| Cinqair | Reslizumab | Asthme à éosinophiles | Complete | August 4, 2016 | March 22, 2017 |
| Cipralex | Oxalate d'escitalopram | Dépression, trouble dépressif majeur (TDM) | Complete | June 8, 2006 | January 24, 2007 |
| Cipralex | Oxalate d'escitalopram | Dépression, trouble dépressif majeur (TDM) | Withdrawn | August 3, 2005 | |
| Ciprodex | Suspension otique de ciprofloxacine et de dexaméthasone | Otite moyenne avec otorrée et otite externe aigüe | Complete | June 11, 2004 | January 26, 2005 |
| Ciprodex | Suspension otique de ciprofloxacine et de dexaméthasone | Otite moyenne avec otorrée et otite externe aigüe | Complete | June 15, 2007 | October 18, 2007 |
| Combigan Ophthalmic Solution | Tartrate de brimonidine et maléate de timolol | Glaucome | Complete | December 15, 2003 | May 27, 2004 |
| COMPLERA | Emtricitabine/rilpivirine/fumarate de ténofovir disoproxil | Infection au VIH-1 chez l'adulte n'ayant jamais subi de traitement antirétroviral | Complete | October 19, 2011 | April 19, 2012 |
| À confirmer | propionate d’halobétasol et tazarotène | Psoriasis en plaques de modéré à grave | Withdrawn | February 4, 2019 | |
| à confirmer | indacatérol, glycopyrronium et furoate de momatésone | Le traitement d’entretien de l’asthme chez l’adulte | En attente | ||
| À confirmer | sémaglutide | Diabète de type 2 | En attente | ||
| À confirmer | filgrastim | Prévention ou le traitement de la neutropénie dans différentes indications | Cancelled | November 1, 2018 | |
| à confirmer | Chlorhydrate d'eskétamine | Trouble dépressif majeur chez les adultes | Active | June 24, 2019 | |
| à confirmer | frémanézumab | La migraine | En attente | ||
| À confirmer | Darunavir / cobicistat | infection par le VIH | Withdrawn | April 4, 2014 | |
| À confirmer | Ravulizumab | Hémoglobinurie paroxystique nocturne | Suspended | July 4, 2019 | |
| à confirmer | indacatérol et furoate de mométasone | Le traitement d’entretien de l’asthme chez l’adulte et l’adolescent de 12 ans ou plus | En attente | ||
| À confirmer | filgrastim | Neutropénie, mobilisation des cellules sanguines (différentes indications) | Cancelled | ||
| À confirmer | Prévention de la grossesse | Withdrawn | September 26, 2019 | ||
| Constella | Linaclotide | Syndrome du colon irritable avec constipation | Complete | December 17, 2014 | September 23, 2015 |
| Contrave | Chlorhydrate de naltrexone et chlorhydrate de bupropion | Active | May 1, 2019 | ||
| Copaxone | Acétate de glatiramère | Syndrome clinique isolé, caractéristique de la sclérose en plaques | Complete | April 29, 2009 | November 25, 2009 |
| Cortiment | Budésonide | Colite ulcéreuse | Complete | May 24, 2016 | March 22, 2017 |
| Cosentyx | Sécukinumab | Arthrite psoriasique | Complete | February 19, 2016 | August 23, 2016 |
| Cosentyx | Sécukinumab | Psoriasis en plaques modéré à grave | Complete | December 8, 2014 | October 28, 2015 |
| Cosentyx | Sécukinumab | Spondylarthrite ankylosante | Complete | February 19, 2016 | August 23, 2016 |
| Nucynta CR | Tapentadol | Douleur d’intensité modérée à modérément grave | Complete | February 1, 2011 | September 28, 2011 |
| Cresemba | Isavuconazole | Traitement de l'aspergillose et de la mucormycose invasives | Complete | November 2, 2018 | May 15, 2019 |
| Crysvita | Burosumab | Traitement de l’hypophosphatémie liée à l’X | Active | July 23, 2019 | |
| Cubicin | Daptomycin | Infections de la peau et des structures cutanées et bactériémie | Complete | March 6, 2008 | September 24, 2008 |
| Cuvposa | Glycopyrrolate | Sialorrhée chronique grave, neurologique | Active | May 31, 2019 | |
| Cymbalta | Duloxetine hydrochloride | Pain, Neuropathic, Diabetic | Complete | February 8, 2008 | August 14, 2008 |
| Cymbalta | Chlorhydrate de duloxétine | Trouble dépressif majeur (TDM) | Complete | February 8, 2008 | August 14, 2008 |
| Cystadrops | Cystéamine | Dépôts cornéens de cristaux de cystine | Complete | December 10, 2018 | June 18, 2019 |
| Daklinza | Daclatasvir | Hépatite C chronique | Complete | February 13, 2015 | September 21, 2015 |
| Daklinza | Daclatasvir | Hépatite C chronique | Complete | January 6, 2016 | May 19, 2016 |
| Daxas | Roflumilast | Maladie pulmonaire obstructive chronique (MPOC) | Complete | November 30, 2010 | July 27, 2011 |
| Delstrigo | doravirine, lamuvidine et fumarate de ténofovir disoproxil | infection par le VIH-1 | Complete | November 16, 2018 | May 14, 2019 |
| Denavir | Penciclovir | Herpès labial (feu sauvage) | Complete | September 20, 2006 | April 26, 2007 |
| Descovy | Emtricitabine /ténofovir alafénamide | Infection par le VIH-1 | Complete | January 29, 2016 | August 24, 2016 |
| Diacomit | Stiripentol | Syndrome de Dravet | Complete | October 30, 2013 | October 16, 2014 |
| Dificid | Fidaxomicine | Infection à Clostridium difficile | Complete | July 10, 2012 | December 19, 2012 |
| Dovato | dolutégravir/lamivudine | Infection par le VIH-1 | Complete | February 21, 2019 | September 30, 2019 |
| Duaklir Genuair | Bromure d’aclidinium et fumarate de formotérol dihydraté | Maladie pulmonaire obstructive chronique (MPOC) | Complete | April 1, 2015 | September 18, 2015 |
| Duobrii | Propionate d'halobétasol et tazarotène | Psoriasis en plaques, modéré à grave | Active | January 24, 2020 | |
| Duodopa | Levodopa / carbidopa | Maladie de Parkinson | Complete | December 19, 2008 | July 22, 2009 |
| Duodopa | lévodopa/carbidopa (demande de régimes d'assurance médicaments) | Maladie de Parkinson | Complete | February 8, 2018 | August 22, 2018 |
| DuoTrav | Travoprost et maléate de timolol | Glaucome | Complete | March 24, 2006 | August 24, 2006 |
| Dupixent | dupilumab | dermatite atopique | Complete | October 27, 2017 | June 27, 2018 |
| Dupixent | dupilumab | dermatite atopique | Active | October 22, 2019 | |
| Dymista | Chlorhydrate d’azélastine et propionate de fluticasone | Rhinite saisonnière | Complete | December 9, 2014 | June 17, 2015 |
| Dysport Therapeutic | abobotulinumtoxinA | Dystonie cervicale | Complete | January 31, 2017 | July 26, 2017 |
| Dysport Therapeutic | abobotulinumtoxinA | spasticité des membres inférieurs | Complete | February 7, 2018 | August 21, 2018 |
| Dysport Therapeutic | abobotulinumtoxinA | Spasticité des membres supérieurs | Complete | April 24, 2017 | October 24, 2017 |
| Ebixa | Chlorhydrate de mémantine | Démence (type Alzheimer) modérée à grave | Complete | December 21, 2004 | November 23, 2005 |
| Edarbi | Azilsartan médoxomil | Hypertension artérielle essentielle | Complete | March 8, 2013 | October 17, 2013 |
| Edarbyclor | Azilsartan médoxomil et chlortalidone | Hypertension artérielle essentielle | Complete | March 8, 2013 | October 17, 2013 |
| Edurant | Rilpivirine | Infection par le HIV (traitement; adulte jamais traité) | Complete | July 29, 2011 | February 15, 2012 |
| Effient | Prasugrel | Syndrome coronarien aigu (SCA) | Complete | December 12, 2011 | June 14, 2012 |
| Effient | Chlorhydrate de prasugrel | Syndrome coronarien aigu (SCA) | Complete | May 5, 2010 | February 16, 2011 |
| Egrifta | Tésamoréline | Lipodystrophie associée à l’infection par le VIH | Complete | March 2, 2016 | August 24, 2016 |
| Elaprase | Idursulfase | mucopolysaccharidose type II, maladie de Hunter | Complete | July 13, 2007 | December 19, 2007 |
| Elelyso | Taliglucérase alfa | Maladie de Gaucher | Complete | August 15, 2014 | October 28, 2015 |
| Eliquis | Apixaban | Prévention des incidents thromboemboliques veineux | Complete | December 20, 2011 | June 14, 2012 |
| Eliquis | Apixaban | Prévention des incidents thromboemboliques (fibrillation auriculaire) | Complete | September 25, 2012 | March 20, 2013 |
| Eliquis | Apixaban | Traitement et prévention de la récurrence de l’incident thromboembolique veineux | Complete | September 18, 2014 | May 7, 2015 |
| Trelegy Ellipta | furoate de fluticasone uméclidinium vilantérol | maladie pulmonaire obstructive chronique (MPOC) | Complete | March 1, 2018 | August 23, 2018 |
| Incruse Ellipta | Uméclidinium | Maladie pulmonaire obstructive chronique (MPOC) | Complete | March 4, 2015 | September 18, 2015 |
| Emend | Aprépitant | Nausées et vomissements causés par la chimiothérapie | Complete | August 29, 2007 | February 20, 2008 |
| Enablex | Bromhydrate de darifénacine | Vessie hyperactive | Complete | April 26, 2006 | October 19, 2006 |
| Enablex | Bromhydrate de darifénacine | Vessie hyperactive | Complete | October 1, 2008 | April 16, 2009 |
| Entresto | Sacubitril/valsartan | Insuffisance cardiaque, classe NYHA II ou III | Complete | September 18, 2015 | March 18, 2016 |
| Entresto | sacubritil/valsartan | Insuffisance cardiaque, classe NYHA II ou III | En attente | ||
| Entyvio | védolizumab | Colite ulcéreuse | Active | November 21, 2019 | |
| Entyvio | Védolizumab | Colite ulcéreuse | Complete | February 20, 2015 | October 28, 2015 |
| Entyvio | Védolizumab | Maladie de Chrohn | Complete | April 27, 2016 | October 27, 2016 |
| Epclusa | Sofosbuvir/velpatasvir | Hépatite C chronique | Complete | April 22, 2016 | October 26, 2016 |
| Erelzi | étanercept | Spondylarthrite ankylosante, polyarthrite juvénile idiopathique, polyarthrite rhumatoïde | Complete | February 2, 2017 | July 25, 2017 |
| Esbriet | Pirfénidone | Fibrose pulmonaire idiopathique, de légère à modérée | Complete | August 29, 2014 | April 15, 2015 |
| Esbriet | Pirfénidone | Fibrose pulmonaire idiopathique, de légère à modérée | Complete | October 5, 2012 | April 18, 2013 |
| Eucrisa | crisaborole | dermatite atopique | Complete | May 25, 2018 | March 27, 2019 |
| Evra | Norgelestromine et éthinylestradiol | Timbre contraceptif | Complete | December 19, 2003 | June 23, 2004 |
| Exelon Patch | Rivastigmine | Démence (type Alzheimer) | Complete | December 21, 2007 | July 23, 2008 |
| Exjade | Déférasirox | Hémochromatose | Complete | October 26, 2006 | April 19, 2007 |
| Eylea | Aflibercept | Œdème maculaire secondaire à une occlusion veineuse rétinienne | Complete | December 14, 2015 | July 27, 2016 |
| Eylea | Aflibercept | Dégénérescence maculaire liée à l'âge | Complete | November 18, 2013 | October 20, 2014 |
| Eylea | Aflibercept | œdème maculaire diabétique | Complete | September 16, 2014 | May 7, 2015 |
| Eylea | Aflibercept | œdème maculaire secondaire à une occlusion de la veine centrale de la rétine | Complete | October 17, 2014 | May 7, 2015 |
| Fabrazyme | Agalsidase bêta | Maladie de Fabry | Complete | December 10, 2004 | May 18, 2005 |
| Fabrazyme | Agalsidase bêta | Maladie de Fabry | Complete | February 24, 2004 | November 24, 2004 |
| Fampyra | Fampridine | Sclérose en plaques, amélioration de la capacité de marche | Withdrawn | November 6, 2014 | |
| Fampyra | Fampridine | Sclérose en plaques, amélioration de la capacité de marche | Complete | April 16, 2012 | November 28, 2012 |
| Fasenra | benralizumab | Asthme grave, éosinophile | Complete | October 24, 2018 | March 27, 2019 |
| Fasenra | benralizumab | Asthme grave, éosinophile | Complete | February 23, 2018 | August 23, 2018 |
| Fentora | Fentanyl buccal | Accès douloureux transitoires, adultes cancéreux | Complete | July 12, 2016 | February 21, 2017 |
| Ferriprox | Défériprone | Surcharge en fer transfusionnelle | Complete | September 24, 2015 | March 18, 2016 |
| Fibristal | Acétate d’ulipristal | Fibromes utérins (signes et symptômes) | Complete | April 17, 2013 | November 15, 2013 |
| Fibristal | acétate d’ulipristal | le traitement des fibromes utérins (signes et symptômes) | Complete | June 21, 2017 | November 22, 2017 |
| Fibristal | Acétate d'ulipristal | Fibromes utérins (signes et symptômes) | Complete | March 28, 2019 | July 24, 2019 |
| Finacea | Acide azélaïque | Rosacée | Complete | August 31, 2010 | February 16, 2011 |
| Firazyr | Icatibant | angioedème héréditaire | Complete | March 4, 2014 | December 19, 2014 |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose | Withdrawn | December 18, 2008 | |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose grave (chez la femme) | Complete | October 23, 2009 | March 17, 2010 |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose induite par les glucocorticoïdes | Complete | December 18, 2008 | July 22, 2009 |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose | Withdrawn | May 29, 2006 | |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose | Complete | June 8, 2004 | December 22, 2004 |
| Forteo | Tériparatide injectable (source ADNr) | Ostéoporose | Withdrawn | June 12, 2009 | |
| Forxiga | Dapagliflozin | Diabète sucré (Type 2) | Complete | April 30, 2015 | November 20, 2015 |
| Forxiga | dapagliflozine | diabète de type 2 | Complete | September 4, 2015 | April 27, 2016 |
| Forxiga | dapagliflozine | L’insuffisance cardiaque à fraction d’éjection réduite | Received | ||
| Fosavance | Alendronate monosodique et cholécalciférol | Ostéoporose | Complete | March 27, 2006 | September 27, 2006 |
| Fosrenol | Carbonate de lanthane hydraté | Hyperphosphatémie, insuffisance rénale terminale | Complete | June 28, 2007 | January 30, 2008 |
| Fulphila | pegfilgrastim | Neutropénie fébrile associée à un cancer non myéloïde | Complete | November 14, 2018 | |
| Fycompa | Pérampanel | Épilepsie, crise tonico-clonique généralisée | Complete | November 24, 2015 | May 18, 2016 |
| Fycompa | Pérampanel | Épilepsie, crises partielles | Complete | March 8, 2013 | October 17, 2013 |
| Galafold | migalastat | Maladie de Fabry | Complete | June 9, 2017 | January 24, 2018 |
| Galexos | Siméprévir | Hépatite C chronique | Complete | August 22, 2013 | June 18, 2014 |
| Gelnique | gel de chlorure d’oxybutynine | Vessie hyperactive | Complete | October 25, 2011 | May 24, 2012 |
| Genotropin | Somatropine | Syndrome de Turner | Complete | May 27, 2013 | December 20, 2013 |
| Genotropin | Somatropine | Carence en hormone de croissance chez l'adulte | Complete | May 27, 2013 | December 20, 2013 |
| Genotropin | Somatropine | Carence en hormone de croissance chez l'enfant | Complete | May 27, 2013 | December 20, 2013 |
| Tudorza Genuair | Bromure d’aclidinium | Maladie pulmonaire obstructive chronique (MPOC) | Complete | August 21, 2013 | April 21, 2014 |
| Genvoya | Elvitégravir/cobicistat/emtricitabine/ténofovir alafénamide | Infection au VIH | Complete | September 24, 2015 | March 18, 2016 |
| Gilenya | Fingolimod | Sclérose en plaques | Complete | May 10, 2011 | November 16, 2011 |
| Glatect | Acétate de glatiramer | Sclérose en plaques cyclique | Complete | January 20, 2017 | July 25, 2017 |
| Grastek | Fléole des prés | Allergie (graminées) | Complete | September 30, 2013 | September 24, 2014 |
| Grastofil | Filgrastim | Prévention ou traitement de la neutropénie sous diverses indications | Complete | September 11, 2015 | March 18, 2016 |
| Harvoni | Lédipasvir/sofosbuvir | Hépatite C chronique | Complete | September 15, 2014 | March 18, 2015 |
| Harvoni | lédipasvir, sofosbuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 18, 2016 |
| Hemangiol | Propranolol | Hémangiome infantile | Withdrawn | December 23, 2014 | |
| Hemangiol | Solution orale de propranolol | Hémangiome infantile | Complete | August 25, 2016 | February 21, 2017 |
| Hepsera | Adéfovir dipivoxil | Hépatite B | Complete | June 29, 2007 | October 18, 2007 |
| Hepsera | Adéfovir dipivoxil | Hépatite B | Complete | April 24, 2006 | November 29, 2006 |
| Holkira Pak | ombitasvir/paritaprévir/ritonavir et dasabuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 26, 2016 |
| Holkira Pak | Ombitasvir/paritaprévir/ritonavir and dasabuvir | Hépathite C chronique | Complete | December 3, 2014 | June 18, 2015 |
| Humira | Adalimumab | Hidrosadénite suppurée | Complete | November 3, 2015 | May 19, 2016 |
| Humira | Adalimumab | Maladie de Crohn | Complete | July 12, 2007 | December 19, 2007 |
| Humira | Adalimumab | Polyarthrite rhumatoïde | Complete | September 24, 2004 | February 11, 2005 |
| Humira | Adalimumab | Arthrite juvénile idiopathique | Complete | February 4, 2013 | July 18, 2013 |
| Humira | Adalimumab | Spondylarthrite ankylosante | Complete | November 17, 2006 | June 27, 2007 |
| Humira | Adalimumab | Colite ulcéreuse | Complete | September 25, 2015 | April 15, 2016 |
| Humira | Adalimumab | Psoriasis | Complete | April 15, 2008 | October 16, 2008 |
| Humira | Adalimumab | Arthrite psoriasique | Complete | June 21, 2006 | November 29, 2006 |
| Humira | Adalimumab | Colite ulcéreuse | Withdrawn | December 23, 2013 | |
| Simponi I.V. | Golimumab | Polyarthrite rhumatoïde | Complete | September 12, 2013 | July 17, 2014 |
| Stelara/Stelara I.V. | ustekinumab | Maladie de Crohn | Complete | September 12, 2016 | March 21, 2017 |
| Stelara/Stelara I.V | ustékinumab | Colite ulcéreuse | Active | August 12, 2019 | |
| Ikervis | cyclosporine | Kératite sévère | Withdrawn | May 15, 2017 | |
| Ilaris | Canakinumab | Syndrome périodique associé à la cryopyrine | Complete | July 7, 2010 | January 26, 2011 |
| Ilaris | Canakinumab | Arthrite idiopathique juvénile systémique | Complete | December 23, 2015 | June 17, 2016 |
| Ilumya | Tildrakizumab | Psoriasis en plaque, modéré à grave | Suspended | July 15, 2019 | |
| Iluvien | implant intravitréen d'acétonide de fluocinolone | œdème maculaire diabétique | Complete | April 3, 2019 | September 26, 2019 |
| Iluvien | fluocinolone acétonide | œdème maculaire diabétique | Withdrawn | December 21, 2017 | |
| Imbruvica | ibrutinib | Réaction chronique du greffon contre l’hôte | NotFiled | ||
| Incivek | Télaprévir | Infection à l'hépatite C (génotype 1), chronique | Complete | August 23, 2011 | February 15, 2012 |
| Incivek | Télaprévir | Hépatite C chronique | Complete | December 21, 2012 | June 13, 2013 |
| Incivek | Télaprévir | Hépatite C chronique | Complete | February 19, 2013 | June 13, 2013 |
| Inflectra | Infliximab | Spondylarthrite ankylosante, psoriasis en plaques, arthrite psoriasique, polyarthrite rhumatoïde | Complete | June 17, 2014 | December 19, 2014 |
| Inspiolto Respimat | Tiotropium / olodatérol | Maladie pulmonaire obstructive chronique (MPOC) (COPD) | Complete | June 4, 2015 | December 17, 2015 |
| Inspra | Éplérénone | Après un infarctus du myocarde | Complete | May 6, 2009 | November 25, 2009 |
| Inspra | Éplérénone | Insuffisance cardiaque, classe II de la NYHA | Complete | July 12, 2013 | April 24, 2014 |
| Intelence | Étravirine | VIH | Complete | April 2, 2008 | August 14, 2008 |
| Intuniv XR | Chlorhydrate de guanfacine | Trouble d'hyperactivité avec déficit de l'attention | Complete | August 27, 2013 | September 24, 2014 |
| Invega | Palipéridone | Schizophrénie | Complete | November 1, 2007 | May 28, 2008 |
| Invega Sustenna | Palmitate de palipéridone | Schizophrénie | Complete | July 9, 2010 | April 25, 2011 |
| Invokamet | Canagliflozine et metformine | Diabète de type 2 | Complete | March 3, 2016 | August 25, 2016 |
| Invokana | Canagliflozine | Diabète de type 2 | Withdrawn | June 5, 2013 | |
| Invokana | Canagliflozine | Diabète de type 2 | Complete | February 24, 2014 | January 15, 2015 |
| Iressa | Géfitinib | Cancer du poumon non à petites cellules | Complete | December 22, 2003 | June 23, 2004 |
| Isentress | Raltégravir | VIH | Complete | November 29, 2007 | May 14, 2008 |
| Isentress | Raltégravir | VIH (patients jamais traités) | Complete | December 4, 2009 | June 23, 2010 |
| Izba | Solution ophtalmique travoprost | Glaucome à angle ouvert | Complete | March 1, 2017 | October 25, 2017 |
| Janumet | Phosphate de sitagliptine monohydraté/chlorhydrate de metformine | Diabète de type 2 | Complete | November 4, 2009 | June 23, 2010 |
| Januvia | Phosphate de sitagliptine | Diabète de type 2 | Complete | October 29, 2009 | June 23, 2010 |
| Januvia | Phosphate de sitagliptine | Diabète de type 2 | Complete | December 20, 2007 | June 18, 2008 |
| Jardiance | Empagliflozine | Diabète sucré type 2 à haut risque cardiovasculaire | Complete | April 27, 2016 | October 26, 2016 |
| Jardiance | Empagliflozine | Diabète sucré de type 2 | Complete | April 23, 2015 | October 15, 2015 |
| Jentadueto | Linagliptine/metformine | Diabète de type 2 | Complete | March 8, 2013 | October 17, 2013 |
| Jetrea | Ocriplasmine | Adhérence vitréomaculaire | Complete | June 6, 2013 | December 20, 2013 |
| Jinarc | Tolvaptan | Polykystose rénale à caractère autosomique dominant (ADPKD) | Complete | May 29, 2015 | February 24, 2016 |
| Jorveza | budésonide | Œsophagite à éosinophiles, adultes | Active | November 8, 2019 | |
| Jublia | éfinaconazole | Onychomycose | Complete | August 2, 2018 | May 23, 2019 |
| Juluca | Dolutégravir rilpivirine | Infection par le VIH | Complete | December 21, 2017 | June 20, 2018 |
| Jurnista | Chlorhydrate d'hydromorphone | Douleur chronique (de modérée à intense) | Complete | December 4, 2009 | May 19, 2010 |
| Juxtapid | Lomitapide | hypercholestérolémie familiale | Complete | July 8, 2014 | April 17, 2015 |
| Kalydeco | Ivacaftor | Fibrose kystique, mutation R117H du gène CFTR | Complete | May 8, 2015 | November 19, 2015 |
| Kalydeco | Ivacaftor | Fibrose kystique (mutation G551D) | Complete | September 27, 2012 | March 22, 2013 |
| Kalydeco | Ivacaftor | Fibrose cystique (mutations de CFTR) | Complete | May 1, 2014 | December 19, 2014 |
| Kanuma | sebelipase alfa | Déficit en lipase acide lysosomique | Complete | November 2, 2017 | September 26, 2018 |
| Kazano | Alogliptine alliée à metformine | diabète de type 2 | Complete | January 30, 2014 | January 15, 2015 |
| Kevzara | sarilumab | Polyarthrite rhumatoïde | Complete | October 12, 2016 | April 18, 2017 |
| Kivexa | Abacavir/lamivudine | Infection au VIH | Complete | July 26, 2005 | December 7, 2005 |
| Komboglyze | Saxagliptine et metformine | Diabète de type 2 | Complete | August 23, 2013 | June 20, 2014 |
| Komboglyze | Saxagliptine et metformine | Diabète de type 2 | Withdrawn | June 6, 2013 | |
| Kuvan | Sapropterin dihydrochloride | Phénylcénoturie | Complete | February 1, 2016 | October 26, 2016 |
| Kuvan | Dichlorhydrate de saproptérine | Phénylcétonurie | Complete | July 8, 2010 | January 26, 2011 |
| Kuvan | Dichlorhydrate de saproptérine | Phénylcétonurie | Complete | June 1, 2011 | |
| Kynmobi | chlorhydrate d'apomorphine | Maladie de Parkinson | Withdrawn | February 25, 2019 | |
| Lancora | Ivabradine | Insuffisance cardiaque, classes NYHA II à III | Complete | November 8, 2016 | May 24, 2017 |
| Lantus | Insuline glargine (source ADNr) | Diabète de type 2 | Complete | February 11, 2005 | September 28, 2005 |
| Lantus | Insuline glargine (source ADNr) | Diabète de type 1 et 2 | Complete | March 27, 2006 | October 25, 2006 |
| Lantus | Insuline glargine (source ADNr) | Diabète de type 1 et 2 | Complete | June 9, 2009 | |
| Lapelga | Pegfilgrastim | Neutropénie fébrile | Complete | February 23, 2018 | |
| Latuda | Lurasidone | Schizophrénie | Complete | July 3, 2012 | January 23, 2013 |
| Latuda | Lurasidone | Schizophrénie | Complete | May 9, 2013 | December 20, 2013 |
| Latuda | lurasidone | Trouble bipolaire de type I | NotFiled | ||
| Lemtrada | Alemtuzumab | Sclérose en plaques rémittente | Withdrawn | October 1, 2013 | |
| Lemtrada | Alemtuzumab | Sclérose en plaques cyclique | Complete | November 27, 2014 | June 18, 2015 |
| Levemir | Insuline détémir | Diabète | Complete | March 10, 2009 | August 20, 2009 |
| Levemir | Insuline détémir | Diabète | Withdrawn | February 2, 2009 | |
| Levemir | Insuline détémir | Diabète | Complete | December 19, 2005 | August 2, 2006 |
| Levemir | Insuline détémir | Diabète de type 1, pédiatrique | Complete | March 10, 2009 | August 20, 2009 |
| Lixiana NVAF | Edoxaban | Fibrillation auriculaire non valvulaire, prévention des accidents vasculaires cérébraux et des embolies systémiques | Complete | September 9, 2016 | March 21, 2017 |
| Lixiana VTE | Edoxaban | Thromboembolie veineuse, traitement et prevention de récurrence | Complete | September 9, 2016 | May 25, 2017 |
| Lodalis | Chlorhydrate de colésévélam | Hypercholestérolémie | Complete | April 27, 2012 | December 19, 2012 |
| Lokelma | Cyclosilicate de zirconium sodique | Hyperkaliémie chez les adultes | Active | May 17, 2019 | March 25, 2020 |
| Lotemax | Étabonate de lotéprednol | Inflammation postopératoire après une chirurgie de la cataracte | Complete | December 2, 2009 | May 19, 2010 |
| Lucentis | Ranibizumab | Dégénération maculaire liée à l'âge | Complete | July 12, 2007 | March 27, 2008 |
| Lucentis | Ranibizumab injectable | œdème maculaire secondaire à une occlusion veineuse rétinienne | Complete | April 25, 2012 | October 18, 2012 |
| Lucentis | Ranibizumab | Néovascularisation choroïdienne due à la myopie | Complete | February 28, 2014 | February 19, 2015 |
| Lucentis | Ranibizumab | œdème maculaire diabétique | Complete | September 14, 2011 | March 19, 2012 |
| Luxturna | voretigène néparvovec | Perte visuelle due à une dystrophie rétinienne héréditaire | En attente | ||
| Lyrica | Prégabaline | Douleur neuropathique | Complete | June 27, 2005 | January 25, 2006 |
| Lyrica | Prégabaline | Neuropathie périphérique diabétique | Complete | March 20, 2009 | September 23, 2009 |
| Pantoloc M | Pantoprazole magnésique | Réduction de la sécrétion d'acide gastrique | Complete | March 17, 2006 | July 20, 2006 |
| Macugen | Pegaptanib sodique | Dégénérescence maculaire liée à l'âge | Complete | October 20, 2005 | May 25, 2006 |
| Mavenclad | cladribine | Sclérose en plaques cyclique | Complete | December 1, 2017 | October 24, 2018 |
| Maviret | Glécaprévir/pibréntasvir | Hépatite C chronique | Complete | June 9, 2017 | January 23, 2018 |
| Mayzent | siponimod | La sclérose en plaques progressive secondaire | Active | September 26, 2019 | |
| MDK-Nitisinone | nitisinone | La tyrosinémie héréditaire de type 1 | Complete | September 29, 2017 | April 25, 2018 |
| Mictoryl | chlorhydrate de propivérine | Vessie hyperactive | Complete | October 14, 2016 | April 19, 2017 |
| Mifegymiso | Mifépristone et misoprostol | Interruption médicale de grossesse | Complete | October 7, 2016 | April 18, 2017 |
| Mifégymiso | Mifépristone et misoprostol | Interruption médicale de la grossesse (âge gestationnel jusqu’éa 49 jours) | Withdrawn | February 12, 2016 | |
| mirabégron | Myrbetriq | Vessie hyperactive | Complete | November 27, 2013 | November 12, 2014 |
| Monoferric | Fer-isomaltoside 1000 | Anémie ferriprive | Active | June 26, 2019 | March 25, 2020 |
| Monoprost | latanoprost | glaucome et hypertension oculaire | Complete | October 25, 2017 | April 24, 2018 |
| Movapo | chlorhydrate d’apomorphine | Maladie de Parkinson | Complete | July 6, 2017 | January 23, 2018 |
| Mozobil | Plérixafor | Mobilisation des cellules souches hématopoïétiques dans le contexte du lymphome malin non hodgkinien et du myélome multiple | Complete | January 24, 2012 | September 26, 2012 |
| Multaq | Chlorhydrate de dronédarone | Fibrillation auriculaire | Complete | September 18, 2009 | May 27, 2010 |
| Myfortic | Mycophénolate sodique | Rejet d'organes après une allogreffe rénale, prophylaxie | Complete | March 3, 2005 | July 8, 2005 |
| Myozyme | Alglucosidase | Maladie de Pompe | Complete | October 10, 2006 | June 14, 2007 |
| Myrbetriq | Mirabégron | Vessie hyperactive | Withdrawn | March 8, 2013 | |
| Naglazyme | Galsulfase (Drug Plan Submission) | mucopolysaccharidose de type VI | Complete | August 20, 2015 | February 19, 2016 |
| Nesina | Alogliptine | diabète de type 2 | Complete | January 30, 2014 | January 15, 2015 |
| Neulasta | Pegfilgrastim | Neutropénie | Complete | March 29, 2004 | October 27, 2004 |
| Neupro | Rotigotine | Maladie de Parkinson | Complete | May 21, 2015 | November 19, 2015 |
| Neupro | Rotigotine | Maladie de Parkinson | Complete | July 31, 2013 | May 28, 2014 |
| Nexavar | Sorafénib (comprimés) | Cancer, hypernéphrome | Complete | July 31, 2006 | February 28, 2007 |
| Nitisinone | Nitisinone | Tyrosinémie de type 1 | Complete | January 25, 2018 | August 23, 2018 |
| Norprolac | Chlorhydrate de quinagolide | Hyperprolactinémie | Complete | December 16, 2004 | September 28, 2005 |
| Norprolac | Chlorhydrate de quinagolide | Hyperprolactinémie | Complete | November 23, 2005 | May 17, 2006 |
| Nplate | Romiplostim | Purpura thrombopénique idiopathique (chronique immun) | Complete | September 29, 2009 | May 27, 2010 |
| Nucala | mépolizumab | L'asthme éosinophile grave | Complete | October 24, 2018 | March 27, 2019 |
| Nucala | Mépolizumab | Asthme, grave à éosinophiles | Complete | December 18, 2015 | June 16, 2016 |
| Nucynta | Chlorhydrate de tapentadol | douleur intense | Complete | April 17, 2018 | October 23, 2018 |
| NuvaRing | Étonogestrel et éthinylestradiol | Anneau contraceptif | Complete | May 5, 2006 | November 29, 2006 |
| Ocaliva | Acide obéticholique | Cholangite biliaire primitive | Complete | December 22, 2016 | July 25, 2017 |
| Ocrevus | ocrélizumab | Forme progressive primaire de sclérose en plaques | Complete | October 26, 2017 | April 26, 2018 |
| Ocrevus | ocrélizumab | Sclérose en plaques cyclique | Complete | May 16, 2017 | November 21, 2017 |
| Odefsey | Emtricitabine, rilpivirine et ténofovir alafénamide | Infection VIH-1 | Complete | November 24, 2016 | May 25, 2017 |
| Ofev | Nintedanib | Fibrose pulmonaire idiopathique (FPI) | Complete | April 23, 2015 | October 15, 2015 |
| Olmetec Plus | Olmésartan médoxomil et hydrochlorothiazide | Hypertension | Complete | November 28, 2008 | May 27, 2009 |
| Olmetec | Olmésartan médoxomil | Hypertension | Complete | November 28, 2008 | May 27, 2009 |
| Olumiant | Baricitinib | Polyarthrite rhumatoïde | Complete | December 20, 2018 | August 2, 2019 |
| Omnaris | Ciclésonide en vaporisateur nasal | Rhinite allergique (saisonnière et perannuelle) | Complete | May 7, 2008 | November 12, 2008 |
| Omnitrope | Somatropine (d'origine ADNr) | Déficit en hormone de croissance chez l'enfant et l'adulte | Complete | June 12, 2009 | |
| Onbrez | Indacatérol | Maladie pulmonaire obstructive chronique (MPOC), bronchodilatateur d'entretien | Complete | February 29, 2012 | August 16, 2012 |
| Onglyza | Saxagliptine | Diabète sucré (type 2) | Complete | November 9, 2009 | June 17, 2010 |
| Onglyza | Saxagliptine | Diabète de type 2 | Complete | May 9, 2013 | November 15, 2013 |
| Onglyza | Saxagliptine | Diabète de type 2 | Withdrawn | May 28, 2012 | |
| Onpattro | Patisiran | La polyneuropathie dans l’amylose de la transthyrétine héréditaire | Complete | January 25, 2019 | July 25, 2019 |
| Onsolis | Citrate de fentanyl | Douleur paroxystique, cancer (adulte) | Withdrawn | May 10, 2011 | |
| Onsolis | Citrate de fentanyl | Douleur paroxystique, cancer (adulte) | Complete | August 22, 2011 | February 15, 2012 |
| Onstryv | safinamide | Maladie de Parkinson | Active | May 29, 2019 | March 25, 2020 |
| Restasis (émulsion ophtalmique) | Cyclosporine | Syndrome de l'œil sec, de modéré à modérément grave | Complete | December 17, 2010 | July 18, 2011 |
| Opsumit | Macitentan | Hypertension pulmonaire | Complete | December 18, 2015 | January 28, 2015 |
| Oralair | Extrait allergénique de pollen de graminées | Rhinite allergique (pollen de graminées) | Complete | September 21, 2012 | March 20, 2013 |
| Orencia | Abatacept | Polyarthrite rhumatoïde | Complete | November 29, 2012 | July 18, 2013 |
| Orencia | Abatacept | Arthrite juvénile idiopathique; arthrite chronique juvénile | Complete | August 29, 2008 | April 22, 2009 |
| Orencia | Abatacept | Polyarthrite rhumatoïde | Complete | December 2, 2009 | June 17, 2010 |
| Orencia | Abatacept | Polyarthrite rhumatoïde | Complete | October 26, 2006 | June 27, 2007 |
| Orfadin | nitisinone | Tyrosinémie héréditaire de type 1 | Complete | August 29, 2017 | February 21, 2018 |
| Orilissa | élagolix | Le traitement des douleurs modérées à intenses associées à l'endométriose | NotFiled | ||
| Orkambi | lumacaftor/ivacaftor | Fibrose kystique, mutation CFTR F508del | Complete | January 28, 2016 | October 26, 2016 |
| Orkambi | lumacaftor/ivacaftor | Fibrose kystique, mutation F.508del chez les patients âgés de 6 ans et plus | Complete | February 22, 2018 | September 26, 2018 |
| Otezla | Apremilast | Arthrite, psoriatique | Complete | June 8, 2015 | December 17, 2015 |
| Otezla | Apremilast | Psoriasis, en plaques modérées à sévères | Complete | October 8, 2014 | July 22, 2015 |
| Otezla | Aprémilast | Psoriasis, modéré à sévère | Complete | March 3, 2016 | October 26, 2016 |
| Ozanex | ozénoxacine | Impétigo | Complete | January 25, 2018 | October 24, 2018 |
| Ozempic | Sémaglutide | Diabète de type 2 | Complete | November 23, 2018 | May 15, 2019 |
| Ozurdex | Dexaméthasone | Œdème maculaire diabétique | Complete | September 26, 2017 | October 24, 2018 |
| Ozurdex | Implant intravitréen de dexaméthasone | Œdème maculaire secondaire à une occlusion veineuse rétinienne | Complete | September 1, 2011 | April 25, 2012 |
| Pegasys RBV | Peginterféron alfa-2a et ribavirine | Hépatite C chronique | Complete | May 14, 2004 | October 14, 2004 |
| Pheburane | Phénylbutyrate de sodium | Troubles du cycle de l'urée | Complete | October 20, 2015 | |
| Picato | Mébutate d’ingénol | Kératose sénile | Complete | May 9, 2013 | January 22, 2014 |
| Picato | Mébutate d'ingénol | Kératose actinique | Complete | May 26, 2014 | |
| Pifeltro | doravirine | infection due au VIH-1 | Complete | November 16, 2018 | May 14, 2019 |
| Plegridy | Peginterféron béta-1a | Sclérose en plaques cyclique | Complete | June 26, 2015 | December 17, 2015 |
| Teveten Plus | Mésylate d'éprosartan et hydrochlorothiazide | Hypertension essentielle | Complete | July 8, 2004 | December 15, 2004 |
| Pradaxa | Dabigatran etexilate | Prévention de l'AVC et de l'embolie systémique en contexte de fibrillation auriculaire | Complete | October 28, 2010 | June 22, 2011 |
| Pradaxa | Dabigatran etexilate | Prévention de la thromboembolie veineuse | Complete | July 8, 2008 | January 28, 2009 |
| Pradaxa | Dabigatran etexilate | Prévention de l'AVC et de l'embolie systémique en contexte de fibrillation auriculaire | Cancelled | May 31, 2010 | |
| Pradaxa | Dabigatran etexilate | Prévention de l'AVC et de l'embolie systémique en contexte de fibrillation auriculaire | Complete | March 18, 2013 | July 18, 2013 |
| Praluent | Alirocumab | Hypercholestérolémie primaire (non-familiale et hétérozygote familiale), dyslipidémie mixte | Complete | January 12, 2016 | July 20, 2016 |
| Praxbind | Idarucizumab (demande d'un régime d'assurance) | neutralisation de l’effet anticoagulant du dabigatran | Withdrawn | May 30, 2016 | |
| Prevymis | létermovir | Infection au cytomégalovirus, prophylaxie | Complete | December 7, 2017 | June 20, 2018 |
| Prexige | Lumiracoxib | Arthrose du genou | Complete | December 15, 2006 | July 25, 2007 |
| Prezcobix | Darunavir/cobicistat | Infection par le VIH | Complete | May 22, 2014 | March 18, 2015 |
| Prezista | Darunavir | Infection par le VIH | Complete | August 29, 2006 | February 14, 2007 |
| Prezista | Darunavir | Infection par le VIH (enfant) | Complete | December 22, 2009 | June 17, 2010 |
| Prezista | Darunavir | Infection par le VIH (patient jamais traité) | Complete | March 27, 2009 | October 14, 2009 |
| Pristiq | Succinate de desvenlafaxine | Trouble dépressif majeur (TDM) | Complete | March 5, 2009 | September 23, 2009 |
| Probuphine | chlorhydrate de buprénorphine | Traitement de la dépendance aux opioïdes | Complete | December 21, 2017 | August 22, 2018 |
| Procysbi | Bitartrate de cystéamine | Cystinose néphropathique | Complete | August 8, 2017 | January 24, 2018 |
| Prolia | Denosumab (Déposé par un régime d’assurance médicaments) | Ostéoporose chez les hommes | Complete | March 10, 2015 | September 21, 2015 |
| Prolia | Dénosumab | Ostéoporose, femmes postménopausiques | Complete | October 26, 2015 | May 20, 2016 |
| Prolia | Dénosumab | Ostéoporose, femmes ménopausées | Complete | August 26, 2010 | March 30, 2011 |
| Quinsair | Lévofloxacine | Fibrose kystique compliquée par des infections pulmonaires chroniques dues à Pseudomas æruginosa | Complete | May 31, 2016 | November 21, 2016 |
| Radicava | édavarone | Sclérose latérale amyotrophique | Complete | July 5, 2018 | March 27, 2019 |
| Ralivia | Chlorhydrate de tramadol | Douleur | Complete | October 29, 2007 | June 25, 2008 |
| RAPAFLO | Silodosine | Hyperplasie bénigne de la prostate | Complete | October 25, 2011 | April 19, 2012 |
| Raptiva | Efalizumab | Psoriasis en plaques chronique, de modéré à grave | Complete | October 25, 2005 | August 24, 2006 |
| Raptiva | Efalizumab | Psoriasis en plaques chronique, de modéré à grave | Complete | June 19, 2007 | |
| Rasilez | Aliskirène | Hypertension | Complete | November 30, 2007 | June 25, 2008 |
| Ravicti | Phénylbutyrate de glycérol | Troubles du cycle de l’urée | Complete | August 30, 2016 | March 21, 2017 |
| Rebif | Interféron (IFN) bêta-1a | Syndrome clinique isolé | Complete | March 8, 2013 | August 15, 2013 |
| Relistor | Bromure de méthylnaltrexone | Constipation, causée par un opioïde | Complete | May 7, 2008 | January 28, 2009 |
| Relpax | Bromhydrate d’élétriptan | Migraine | Complete | September 21, 2004 | March 23, 2005 |
| Remicade | Infliximab | Colite ulcéreuse | Complete | September 29, 2008 | April 22, 2009 |
| Remodulin | Sodium de tréprostinil | Hypertension pulmonaire (patients de catégories III et IV de la NYHA) | Complete | February 24, 2006 | July 20, 2006 |
| Remodulin | Sodium de tréprostinil | Hypertension pulmonaire (patients de catégories III et IV de la NYHA) | Complete | July 14, 2004 | November 17, 2004 |
| Remsima | Infliximab | Spondylarthrite ankylosante, psoriasis en plaques, arthrite psoriasique, arthrite rhumatoïde | Withdrawn | May 30, 2014 | |
| Renflexis | infliximab | arthrite rhumatoïde, spondylarthrite ankylosante, maladie de Crohn chez l’adulte, maladie de Crohn pédiatrique, maladie de Crohn fistuleuse, colite ulcéreuse chez l’adulte, colite ulcéreuse pédiatrique, arthrite psoriasique, psoriasis en plaques | Complete | September 5, 2017 | February 20, 2018 |
| Repatha | Evolocumab | hyperlipidémie primaire et dyslipidémie mixte | Complete | February 17, 2017 | November 22, 2017 |
| Repatha | Évolocumab | Hyperlipédémie primaire, dyslipédémie mixte, hypercholestérolémie familiale homozygote | Complete | June 30, 2015 | February 19, 2016 |
| Replagal | Agalsidase alfa | Maladie de Fabry | Complete | February 19, 2004 | November 24, 2004 |
| Resotran | Prucalopride | Constipation chronique | Complete | January 30, 2012 | July 19, 2012 |
| Spiriva Respimat | Bromure de tiotropium | Maladie pulmonaire obstructive chronique (MPOC) | Complete | December 23, 2014 | July 16, 2015 |
| Revatio | Citrate de sildénafil | Hypertension pulmonaire (catégories II et III de l'OMS) | Complete | September 20, 2006 | February 14, 2007 |
| Revestive | téduglutide | Syndrome de l’intestin court (SIC) | Complete | November 26, 2015 | July 27, 2016 |
| Revestive | Téduglutide | Syndrome du grêle court (SGC), pédiatrique | Complete | May 29, 2019 | November 19, 2019 |
| Revolade | Eltrombopag | Thrombocytopénie associée à l’hépatite C | Complete | March 31, 2014 | March 18, 2015 |
| Revolade | eltrombopag | Anémie aplastique grave | NotFiled | ||
| Revolade | Eltrombopag olamine | Purpura thrombopénique chronique immunitaire (idiopathique) | Complete | April 26, 2011 | October 24, 2011 |
| Rexulti | Brexpiprazole | Schizophrénie | Complete | February 3, 2017 | November 22, 2017 |
| Reyataz | Atazanavir | Infection par le VIH | Complete | December 16, 2003 | May 27, 2004 |
| Rinvoq | upadacitinib | Polyarthrite rhumatoïde | Complete | July 4, 2019 | February 4, 2020 |
| Rituxan | Rituximab | Granulomatose avec polyangéite (GPA) et polyangéite microscopique, induction de la rémission (adulte) | Complete | February 24, 2012 | August 16, 2012 |
| Rituxan | Rituximab | Polyarthrite rhumatoïde | Complete | June 26, 2006 | February 14, 2007 |
| Rosiver | Ivermectine | Rosacée | Complete | April 30, 2015 | November 19, 2015 |
| Samsca | Tolvaptan | Hyponatrémie, non hypovolémique | Complete | July 3, 2012 | February 13, 2013 |
| Saphris | Asénapine | Schizophrénie | Complete | December 12, 2011 | June 14, 2012 |
| Saphris | Asénapine | Trouble bipolaire de type I | Complete | December 12, 2011 | June 14, 2012 |
| Sativex | Delta-9-tétrahydrocannabinol et cannabidiol | Douleur cancéreuse (analgésie d'appoint à la dose maximale tolérée d'opioïdes) | Complete | August 7, 2007 | February 20, 2008 |
| Sativex | Delta-9-tétrahydrocannabinol et cannabidiol | Douleur neuropathique (appoint) en contexte de SP | Complete | February 27, 2007 | September 26, 2007 |
| Sebivo | Telbivudine | Hépatite B (chronique) | Complete | December 4, 2006 | September 26, 2007 |
| Seebri | Bromure de glycopyrronium | Maladie pulmonaire obstructive chronique (MPOC), traitement bronchodilatateur d'entretien | Complete | November 30, 2012 | May 15, 2013 |
| Segluromet | Ertugliflozine et chlorhydrate de metformine | Diabète de type 2 | Complete | April 30, 2018 | January 23, 2019 |
| Semglee | Insuline glargine | Diabète sucré, type 1 et 2 | Withdrawn | November 14, 2018 | |
| Sensipar | Chlorhydrate de cinacalcet | Hyperparathyroïdisme secondaire dans la maladie rénale chronique | Complete | August 20, 2004 | March 23, 2005 |
| Signifor | Pasiréotide diaspartate | Maladie de Cushing | Complete | February 27, 2014 | February 24, 2015 |
| Siliq | Brodalumab | Psoriasis en plaques, modéré ou grave | Complete | December 14, 2017 | June 20, 2018 |
| Silkis | Calcitriol | Psoriasis en plaques, de léger à modéré | Complete | March 15, 2010 | September 22, 2010 |
| Simbrinza | Brinzolamide / brimonidine | Glaucome et hypertension oculaire | Complete | November 3, 2014 | June 17, 2015 |
| Simponi | Golimumab | Polyarthrite rhumatoïde | Complete | September 3, 2009 | March 17, 2010 |
| Simponi | Golimumab | Spondylarthrite ankylosante | Complete | September 3, 2009 | March 17, 2010 |
| Simponi | Golimumab | Rectocolite hémorragique | Complete | July 12, 2013 | March 19, 2014 |
| Simponi | Golimumab | Arthrite psoriasique | Complete | September 3, 2009 | March 17, 2010 |
| Sivextro | Phosphate de tédizolid | Infections bactériennes aigües de la peau et des structures cutanées | Withdrawn | January 16, 2015 | |
| Skyrizi | risankizumab | Le psoriasis en plaques modéré à grave | Complete | October 22, 2018 | May 28, 2019 |
| Soliqua | lixisénatide et insuline glargine | Diabète de type 2 | Complete | May 18, 2018 | December 24, 2018 |
| Soliris | Éculizumab | Syndrome hémolytique et urémique atypique | Complete | January 7, 2013 | July 18, 2013 |
| Soliris | éculizumab | Le trouble du spectre de la neuromyélite optique | Active | February 25, 2020 | |
| Soliris | Éculizumab | Hémoglobinurie paroxystique nocturne | Complete | September 18, 2009 | February 18, 2010 |
| Soliris | éculizumab | Myasthénie grave, adultes | Received | April 1, 2020 | |
| Soliris | Éculizumab | syndrome hémolytique et urémique, atypique | Complete | February 9, 2015 | |
| Somavert | Pegvisomant | Acromégalie | Complete | January 25, 2006 | August 2, 2006 |
| Sovaldi | sofosbuvir | Hépatite C, chronique | Complete | January 6, 2016 | May 18, 2016 |
| Sovaldi | Sofosbuvir | Hépatite C, chronique | Complete | October 1, 2013 | August 18, 2014 |
| Spinraza | nusinersen | amyotrophie spinale | Complete | June 28, 2017 | December 22, 2017 |
| Spinraza | Nusinersen | Amyotrophie spinale | Complete | July 24, 2018 | February 27, 2019 |
| Spriafil | Posaconazole | Infections par aspergillus et candida | Complete | May 24, 2007 | January 30, 2008 |
| Stalevo | Lévodopa, carbidopa et entacapone | Maladie de Parkinson | Complete | April 15, 2008 | October 16, 2008 |
| Steglatro | Diabète de type 2 | Complete | April 30, 2018 | January 23, 2019 | |
| Stelara | Ustekinumab | Psoriasis | Complete | January 7, 2009 | June 17, 2009 |
| Stelara | Ustekinumab | Arthrite psoriasique | Complete | October 30, 2013 | October 20, 2014 |
| Strattera | Chlorhydrate d'atomoxétine | Trouble de déficit de l’attention avec hyperactivité | Complete | September 25, 2006 | |
| Strattera | Chlorhydrate d'atomoxétine | Trouble de déficit de l’attention avec hyperactivité | Complete | January 25, 2005 | September 28, 2005 |
| Strensiq | Asfotase alfa | Hypophosphatasie, Durant l’enfance | Complete | August 21, 2015 | March 23, 2016 |
| Stribild | Elvitégravir/cobicistat/emtricitabine/fumarate de ténofovir disoproxil | Infection par le VIH-1 | Complete | November 30, 2012 | May 15, 2013 |
| Sublinox | Tartrate de zolpidem | Insomnie, traitement à court terme | Complete | March 7, 2013 | September 25, 2013 |
| Sublocade | Buprénorphine | Traitement du trouble de consommation d'opioïdes | Complete | December 20, 2018 | June 19, 2019 |
| Suboxone | Buprénorphine/naloxone | Dépendance aux opioïdes (traitement de substitution) | Complete | March 6, 2008 | September 24, 2008 |
| Sunvepra | Asunaprévir | Hépatite C chronique | Complete | February 13, 2015 | July 20, 2016 |
| Sutent | Sunitinib | Tumeur stromale gastro-intestinale | Complete | July 20, 2006 | March 28, 2007 |
| Sutent | Malate de sunitinib | Cancer, adénocarcinome rénal métastatique | Complete | September 20, 2006 | April 26, 2007 |
| Symdeko | tézacaftor/ivacaftor | Fibrose kystique, mutation(s) F508del | NotFiled | ||
| Symtuza | Darunavir/cobicistat/emtricitabine/ténofovir alafénamide | Infection par le VIH-1 | Complete | December 22, 2017 | July 25, 2018 |
| Synjardy | Empagliflozine et metformine | Diabète de type 2 | Complete | April 29, 2016 | October 25, 2016 |
| Takhzyro | lanadélumab | Angio-œdème héréditaire, prévention | Complete | May 29, 2019 | November 19, 2019 |
| Taltz | ixékizumab | Spondylarthrite ankylosante | Active | September 20, 2019 | March 24, 2020 |
| Taltz | ixékizumab | Arthrite psoriasique évolutive | Complete | February 20, 2018 | August 21, 2018 |
| Taltz | Ixékizumab | Psoriasis en plaques modéré à sévère | Complete | March 23, 2016 | October 25, 2016 |
| Tarceva | Erlotinib | Cancer du poumon non à petites cellules | Complete | July 19, 2005 | December 7, 2005 |
| Targin | Chlorhydrate d'oxycodone et chlorhydrate de naloxone | Douleur, de modérée à intense; soulagement de la constipation causée par les opioïdes | Complete | July 5, 2011 | January 25, 2012 |
| Targin | Oxycodone / naloxone | Douleur, de modérée à intense; soulagement de la constipation causée par les opioïdes | Cancelled | November 30, 2010 | |
| Tecfidera | Fumarate de diméthyle | Sclérose en plaques cyclique | Complete | February 4, 2013 | September 25, 2013 |
| Technivie | ombitasvir/ paritaprévir/ ritonavir | hépatite C chronique, VHC de génotype 4 | Complete | September 4, 2015 | March 18, 2016 |
| Tegsedi | inotersen | amylose héréditaire liée à la transthyrétine | Complete | February 22, 2019 | December 18, 2019 |
| Telzir | Fosamprénavir calcique | Infection par le VIH | Complete | January 24, 2005 | June 16, 2005 |
| Thelin | Sodium de sitaxsentan | Hypertension pulmonaire (classes II et III de l'OMS) | Complete | May 5, 2008 | January 28, 2009 |
| Thelin | Sodium de sitaxsentan | Hypertension pulmonaire (classes II et III de l'OMS) | Complete | June 22, 2007 | January 30, 2008 |
| Tivicay | Dolutégravir | Infection par le VIH | Complete | October 18, 2013 | August 18, 2014 |
| Toctino | Alitrétinoïne | Eczéma | Complete | May 6, 2011 | October 24, 2011 |
| Toviaz | Fumarate de fésotérodine | Vessie hyperactive | Complete | April 27, 2012 | October 18, 2012 |
| Trajenta | Linagliptine | Diabète de type 2 | Complete | August 23, 2011 | February 15, 2012 |
| Tramacet | Chlorhydrate de tramadol et acétaminophène | Douleur aigüe | Complete | October 2, 2006 | May 17, 2007 |
| Translarna | ataluren | La dystrophinopathie | Cancelled | ||
| Trelstar | Pamoate de triptoréline | Cancer de la prostate | Complete | February 27, 2006 | July 20, 2006 |
| Tremfya | Psoriasis en plaques de modéré à sévère | Complete | August 25, 2017 | February 21, 2018 | |
| Tresiba | insuline dégludec | Diabète sucré, types 1 et 2 | Complete | May 31, 2017 | November 20, 2017 |
| Tridural | Chlorhydrate de tramadol | Douleur | Complete | November 29, 2007 | April 17, 2008 |
| Trintellix | bromhydrate de vortioxétine | trouble dépressif majeur (TDM) chez les adultes | Active | May 1, 2019 | February 12, 2020 |
| Trintellix | Vortioxetine | Trouble dépressif majeur | Withdrawn | October 31, 2014 | |
| Triumeq | Dolutégravir / abacavir / lamivudine | Infection par le VIH | Complete | July 31, 2014 | April 17, 2015 |
| Trosec | Chlorure de trospium | Vessie hyperactive | Complete | March 24, 2006 | August 24, 2006 |
| Trulicity | dulaglutide | Diabète sucré, type 2 | Complete | December 22, 2015 | June 16, 2016 |
| Truvada | Emtricitabine/fumarate de ténofovir disoproxil | Infection par le VIH | Complete | May 29, 2006 | October 25, 2006 |
| Truvada | Emtricitabine/fumarate de ténofovir disoproxil | Infection par le VIH | Complete | July 7, 2008 | December 17, 2008 |
| Truvada | Emtricitabine/fumarate de ténofovir disoproxil | Infection par le VIH, prophylaxie préexposition | Complete | March 3, 2016 | August 24, 2016 |
| Twynsta | Telmisartan et amlodipine | Hypertension essentielle | Complete | August 23, 2011 | December 16, 2011 |
| Twynsta | Telmisartan et amlodipine | Hypertension essentielle | Cancelled | July 9, 2010 | |
| Tysabri | Natalizumab | Sclérose en plaques cyclique | Complete | May 6, 2008 | February 25, 2009 |
| Tysabri | Natalizumab | Sclérose en plaques cyclique | Complete | October 26, 2006 | April 26, 2007 |
| Uloric | Fébuxostat | Goutte | Complete | October 27, 2010 | April 25, 2011 |
| Uptravi | Sélexipag | Hypertension artérielle pulmonaire (OMS) de classe II et III | Complete | March 31, 2016 | October 28, 2016 |
| Vantas | Acétate d´histréline | Cancer, prostate | Complete | September 20, 2006 | April 26, 2007 |
| Vascepa | acide éthyl-eicosapentaénoïque | Évènements ischémiques chez les patients traités aux statines | Active | June 17, 2019 | |
| Velphoro | oxyhydroxyde sucro-ferrique | hyperphosphatémie, insuffisance rénale terminale | Complete | June 12, 2018 | January 2, 2019 |
| Vemlidy | ténofovir alafénamide | Hépatite B chronique | Complete | September 28, 2017 | March 26, 2018 |
| Verkazia | Cyclosporine | Kératoconjonctivite vernale grave, pédiatrique (≥4 ans) | Complete | May 22, 2019 | November 18, 2019 |
| Vesicare | Succinate de solifénacine | Vessie hyperactive | Complete | January 5, 2009 | June 17, 2009 |
| Vesicare | Succinate de solifénacine | Vessie hyperactive | Complete | July 24, 2006 | January 24, 2007 |
| VesiFlow | Succinate de solifénacine / chlorhydrate de tamsulosine | hyperplasie bénigne de la prostate (HBP)-associée à des symptômes des voies urinaires inférieures | Withdrawn | April 6, 2015 | |
| VFEND | Voriconazole | Candidémie | Complete | March 24, 2006 | October 25, 2006 |
| VFEND | Voriconazole | Aspergillose, invasive | Complete | October 25, 2004 | April 14, 2005 |
| VFEND | Voriconazole | Aspergillose invasive | Withdrawn | August 24, 2004 | |
| Viacoram | perindopril arginine / bésylate d’amlodipine | Hypertension essentielle | Complete | May 2, 2016 | October 26, 2016 |
| Viberzi | éluxadoline | Syndrome du côlon irritable avec diarrhée | Complete | February 23, 2018 | August 24, 2018 |
| Victoza | Liraglutide | Diabète de type 2 | Complete | November 29, 2010 | September 28, 2011 |
| Victoza | Liraglutide | Diabète de type 2 | Withdrawn | October 20, 2016 | |
| Victrelis | Boceprevir | Hepatitis C infection, chronic | Complete | February 19, 2013 | June 13, 2013 |
| Victrelis | Bocéprévir | Hépatite C chronique | Complete | May 3, 2011 | October 24, 2011 |
| Victrelis | Bocéprévir | Hépatite C chronique | Complete | December 21, 2012 | June 13, 2013 |
| Viibryd | vilazodone | Dépression, trouble dépressif caractérisé | NotFiled | ||
| Vimizim | élosulfase alfa | Mucopolysaccharidose IVA (syndrome de Morquio) | Complete | August 5, 2014 | March 25, 2015 |
| Vimizim | Élosulfase alfa | Mucopolysaccharidose IVA (syndrome de Morquio A) | Complete | November 10, 2015 | May 20, 2016 |
| Vimpat | Lacosamide | Crises épileptiques partielles | Complete | October 25, 2010 | April 25, 2011 |
| Viread | Fumarate de ténofovir disoproxil | Infection par le VIH | Complete | February 23, 2004 | August 25, 2004 |
| Viread | Fumarate de ténofovir disoproxil | Infection par le VIH | Complete | August 11, 2005 | March 15, 2006 |
| Viread | Fumarate de ténofovir disoproxil | Hépatite B chronique | Complete | October 2, 2008 | March 18, 2009 |
| Viread | Fumarate de ténofovir disoproxil | Infection par le VIH | Complete | July 7, 2008 | |
| Visanne | Dienogest | Douleur pelvienne liée à l’endométriose | Complete | October 18, 2011 | April 19, 2012 |
| Volibris | Ambrisentan | Hypertension pulmonaire (classes II et III de l'OMS) | Complete | July 9, 2008 | December 17, 2008 |
| Vonvendi | Facteur Willebrand [recombinant] | Maladie de von Willebrand, adulte, traitement et prise en charge périopératoire | En attente | ||
| Vosevi | Sofosbuvir/velpatasvir/voxilaprévir | Hépatite C chronique | Complete | July 28, 2017 | January 23, 2018 |
| VPRIV | Vélaglucérase alfa | Maladie de Gaucher | Complete | October 28, 2010 | April 25, 2011 |
| Vyndaqel | Tafamidis | Amyloïdose à transthyrétine | Active | July 4, 2019 | February 19, 2020 |
| Vyvanse | Dimésylate de lisdexamfétamine | Trouble déficitaire de l’attention avec hyperactivité | Complete | July 10, 2009 | December 18, 2009 |
| Vyzulta | Latanoprostène bunod | Glaucome à angle ouvert ou hypertension oculaire | Complete | November 23, 2018 | July 24, 2019 |
| Xarelto | Rivaroxaban | Accidents thromboemboliques (veineux), embolie pulmonaire | Complete | May 6, 2013 | March 26, 2014 |
| Xarelto | Rivaroxaban | Thromboembolie (veineuse), prévention | Complete | June 24, 2011 | |
| Xarelto | Rivaroxaban | Prévention de l’accident vasculaire cérébral et d'évènements cardiovasculaires causés par la coronopathie ou la maladie artérielle périphérique | Complete | May 24, 2018 | November 20, 2018 |
| Xarelto | Rivaroxaban | Thromboembolie (veineuse), prévention | Complete | May 7, 2008 | December 17, 2008 |
| Xarelto | Rivaroxaban | Traitement de la thrombose veineuse profonde sans embolie pulmonaire symptomatique | Complete | February 27, 2012 | August 16, 2012 |
| Xarelto | Rivaroxaban | Prévention de l’accident vasculaire cérébral en présence de fibrillation auriculaire | Complete | October 21, 2011 | April 19, 2012 |
| Xarelto | Rivaroxaban | Traitement de la thrombose veineuse profonde sans embolie pulmonaire symptomatique | Complete | October 10, 2012 | |
| Xarelto | Rivaroxaban | Prévention de l’accident vasculaire cérébral en présence de fibrillation auriculaire | Complete | March 18, 2013 | July 18, 2013 |
| Xeljanz | Tofacitinib | Polyarthrite rhumatoïde | Complete | May 5, 2014 | April 17, 2015 |
| Xeljanz | tofacitinib | Colite ulcéreuse | Complete | June 27, 2018 | February 27, 2019 |
| Xeljanz | Tofacitinib | Polyarthrite psoriasique | Cancelled | ||
| Xeomin | Neurotoxine de Clostridium botulinum de type A sans protéines complexantes | Blépharospasme | Complete | June 12, 2009 | December 16, 2009 |
| Xeomin | Neurotoxine de Clostridium botulinum de type A sans protéines complexantes | Dystonie cervicale | Complete | June 12, 2009 | December 16, 2009 |
| Xeomin | Neurotoxine de Clostridium botulinum de type A sans protéines complexantes | Spasticité consécutive à un accident vasculaire cérébral | Complete | June 12, 2009 | December 16, 2009 |
| Xermelo | télotristat | syndrome carcinoïde | Complete | September 27, 2018 | June 26, 2019 |
| Xgeva | Denosumab (demande pour régimes d'assurance) | Prévention des complications squelettiques causées par des métastases osseuses découlant du cancer du sein | Complete | July 31, 2015 | February 25, 2016 |
| Xgeva | Denosumab (demande de régimes d'assurance médicaments) | Prévention des complications osseuses dues aux métastases osseuses d’une tumeur solide (sauf le cancer du sein ou de la prostate), y compris le cancer du poumon non à petites cellules | Complete | July 31, 2015 | March 23, 2016 |
| XGEVA | Denosumab | prévention des complications osseuses dues aux métastases osseuses d’une tumeur solide | Complete | June 6, 2011 | November 16, 2011 |
| Xiaflex | Collagénase de Clostridium histolyticum | Maladie de Dupuytren avec cordon palpable | Complete | August 30, 2012 | March 27, 2013 |
| XigDuo | dapagliflozin/metformin hydrochloride | Diabète de type 2 | Active | January 7, 2016 | July 20, 2016 |
| Zytram XL | Chlorhydrate de tramadol | Douleur aigüe | Withdrawn | November 3, 2006 | |
| Zytram XL | Chlorhydrate de tramadol | Douleur aigüe | Complete | March 15, 2007 | September 26, 2007 |
| Xolair | Omalizumab | Asthme sévère persistant | Cancelled | April 18, 2005 | |
| Xolair | Omalizumab (Déposé par un régime d’assurance médicaments) | Asthme grave persistent | Complete | November 18, 2015 | May 18, 2016 |
| Xolair | Omalizumab | Asthme sévère persistant | Complete | October 13, 2005 | March 7, 2006 |
| Xolair | Omalizumab | Urticaire, idiopathique chronique | Complete | September 22, 2014 | May 7, 2015 |
| Xultophy | insuline dégludec et liraglutide | Diabète sucré de type 2 | Complete | January 30, 2019 | October 24, 2019 |
| Xyrem | Oxybate de sodium | Narcolepsie | Complete | July 9, 2008 | January 28, 2009 |
| Xyrem | Oxybate de sodium | Narcolepsie | Withdrawn | August 29, 2007 | |
| Yasmin | Drospirénone et éthinylestradiol | Contraceptif oral | Complete | January 20, 2005 | June 16, 2005 |
| Zavesca | Miglustat | Maladie de Gaucher | Complete | May 13, 2004 | November 24, 2004 |
| Zaxine | Rifaximine | Encéphalopathie hépatique | Complete | August 5, 2014 | April 16, 2015 |
| Zeldox | Chlorhydrate de ziprasidone | Schizophrénie et troubles psychotiques apparentés | Complete | January 10, 2008 | August 14, 2008 |
| Zenhale | Mométasone et formotérol | Asthme, traitement d'entretien (adultes et enfants de 12 ans ou plus) | Complete | June 6, 2012 | December 19, 2012 |
| Zepatier | Elbasvir / grazoprévir | Hépatite C chronique | Complete | October 27, 2015 | May 19, 2016 |
| Zinbryta | Daclizumab bêta | Sclérose en plaques cyclique | Complete | December 20, 2016 | June 20, 2017 |