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Gabapentin, Celecoxib, and Acetaminophen for the Prevention of Post-Operative Pain: Clinical Effectiveness

Last updated: July 31, 2017
Project Number: RB1124-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of pre-operative administration of gabapentin to reduce post-operative pain following orthopedic surgery?
  2. What is the clinical effectiveness of pre-operative administration of celecoxib to reduce post-operative pain following orthopedic surgery?
  3. What is the clinical effectiveness of pre-operative administration of acetaminophen to reduce post-operative pain following orthopedic surgery?

Key Message

Five randomized controlled trials were identified regarding the clinical effectiveness of pre-operative administration of gabapentin, celecoxib, or acetaminophen for patients undergoing orthopedic surgical procedures.