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Gabapentin, Celecoxib, and Acetaminophen for the Prevention of Post-Operative Pain: Clinical Effectiveness

Published on: July 31, 2017
Project Number: RB1124-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of pre-operative administration of gabapentin to reduce post-operative pain following orthopedic surgery?
  2. What is the clinical effectiveness of pre-operative administration of celecoxib to reduce post-operative pain following orthopedic surgery?
  3. What is the clinical effectiveness of pre-operative administration of acetaminophen to reduce post-operative pain following orthopedic surgery?

Key Message

Five randomized controlled trials were identified regarding the clinical effectiveness of pre-operative administration of gabapentin, celecoxib, or acetaminophen for patients undergoing orthopedic surgical procedures.

Tags

acetaminophen, orthopedic procedures, orthopedics, premedication, preoperative care, preoperative period, musculoskeletal, surgery, gabapentin, Neurontin, celecoxib, celebrex, paracetamol, Tylenol, postoperative pain, post-operative pain, preemptive analgesia, pre-operative