While the use of indirect comparisons is increasing, reporting often lacks an adequate description of the methodology used. The research community has identified a need for clarity on appropriate methods and reporting of indirect comparisons.
The goal of this document is to provide guidance on a standard reporting structure for indirect comparisons to establish greater transparency. With transparent reporting, the rigour of the approach and results of the analysis can be assessed.
Of note: this is not a technical guidance document (nor a methodological “how to”), but is limited to providing guidance on reporting methods and results of indirect comparisons. For guidance on indirect comparison methodology, please see the reference documents that are cited within the document.