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Heparin Lock Solutions for Open-Ended Vascular Access Devices: An Update Regarding the Clinical Effectiveness, Safety, and Guidelines

Last updated: September 13, 2017
Project Number: RA0929-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Reference List
Result type: Report

Question

  1. What is the clinical effectiveness of heparin lock solutions to maintain the patency of open-ended central vascular access devices?
  2. What are the evidence-based guidelines associated with the use of heparin lock solutions to maintain the patency of open-ended central vascular access devices?

Key Message

Three systematic reviews, 18 randomized controlled trials, and 11 non-randomized studies were identified regarding the clinical effectiveness of heparin lock solutions to maintain the patency of open-ended central vascular access devices.