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Intrathecal Bupivacaine via Infusion Pump for the Management of Pain: Clinical Evidence, Safety, and Guidelines

Published on: November 21, 2012
Project Number: RB0546-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical-effectiveness of bupivacaine when administered as an intrathecal infusion via an infusion pump for patients requiring enhanced pain control?
  2. What is the clinical evidence regarding the safety of bupivacaine when administered as an intrathecal infusion via an infusion pump for patients requiring enhanced pain control?
  3. What is the clinical evidence regarding the stability of bupivacaine when administered intrathecally via an infusion pump?
  4. What are the evidence-based guidelines regarding the use of intrathecal bupivacaine administration via infusion pump in patients requiring pain management?

Key Message

One systematic review, one randomized controlled trial, and three non-randomized studies were identified regarding bupivacaine administered as an intrathecal infusion via an infusion pump. No relevant evidence-based guidelines were identified.

Tags

bupivacaine, infusion pumps, injections, marcaine, sensorcaine, injections, spinal, intraspinal injections, pain, pain management, anesthesia, Spinal Sensorcaine, Intraspinal, Vivacaine, Infusions, **Intraspinal