Question
- What is the clinical effectiveness of the off-label use of intravenous or subcutaneous immunoglobulin for the treatment of hematological conditions?
Key Message
Three systematic reviews (one with meta-analyses), four randomized controlled trials, and four non-randomized studies were identified regarding the clinical effectiveness of the off-label use of intravenous or subcutaneous immunoglobulin for the treatment of hematological conditions.