Question
- What is the evidence for the safety or harms of long-acting beta2-agonists for patients with chronic obstructive pulmonary disease (COPD), with regards to cardiac arrhythmia?
Key Message
Twelve randomized controlled trials and five non-randomized studies were identified on the safety or harms of long-acting beta2-agonists for patients with chronic obstructive pulmonary disease, with regards to cardiac arrhythmia.