Details
Question
- What is the clinical effectiveness of pre-operative nasal decolonization, with or without chlorhexidine gluconate washes or wipes, for the prevention of surgical site infections?
- What is the cost-effectiveness of pre-operative nasal decolonization, with or without chlorhexidine gluconate washes or wipes, for the prevention of surgical site infections?
- What are the evidence-based guidelines regarding pre-operative interventions for the prevention of surgical site infections?
Key Message
One overview of reviews, five systematic reviews (three with meta-analyses), and four randomized controlled trials were identified regarding the clinical effectiveness of pre-operative nasal decolonization, with or without chlorhexidine gluconate washes or wipes, for the prevention of surgical site infections. Additionally, one economic evaluation was identified regarding the cost-effectiveness of pre-operative nasal decolonization, with or without chlorhexidine gluconate washes or wipes, for the prevention of surgical site infections. Furthermore, eight evidence-based guidelines were identified regarding pre-operative interventions for the prevention of surgical site infections.