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Nitrofurantoin Administration in Patients with Renal Dysfunction: Clinical Effectiveness, Safety, and Guidelines

Published on: January 24, 2013
Project Number: RB0559-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of nitrofurantion for the treatment of infections in patients with a creatinine clearance lower than 60 mL/minute?
  2. What is the safety of nitrofurantion for the treatment of infections in patients with a creatinine clearance lower than 60 mL/minute?
  3. What are the evidence based guidelines regarding the use of nitrofurantion in patients with a creatinine clearance lower than 60 mL/minute

Key Message

One evidence-based guideline was identified regarding the use of nitrofurantoin in patients with a creatinine clearance lower than 60 mL/minute.

Tags

kidney diseases, furadantin, kidney, nitrofurantoin, kidney/urologic, Nitrofurantoin macrobid, Renal, creatinine clearance