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Propofol for Conscious Sedation During Endoscopies: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Last updated: November 14, 2017
Project Number: RB1157-000
Product Line: Rapid Response
Research Type: Drug
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the comparative clinical effectiveness of propofol versus fentanyl or midazolam for conscious sedation during endoscopy procedures?
  2. What is the cost-effectiveness of propofol versus fentanyl or midazolam for conscious sedation during endoscopy procedures?
  3. What are the evidence-based guidelines for the use of propofol for conscious sedation during endoscopy procedures?

Key Message

One systematic review, three randomized controlled trials, and two non-randomized studies were identified regarding propofol for conscious sedation during endoscopies. Additionally, two evidence-based guidelines were identified.