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Radical Prostatectomy and Radiation Therapy for Prostate Cancer: Clinical Effectiveness and Guidelines

Last updated: September 5, 2019
Project Number: RA1061-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Reference List
Result type: Report

Question

  1. What is the clinical effectiveness of radical prostatectomy for early-stage or screen-detected prostate cancer?
  2. What is the clinical effectiveness of radiation therapy for early-stage or screen-detected prostate cancer?
  3. What are the evidence-based guidelines on the use of radical prostatectomy for prostate cancer?
  4. What are the evidence-based guidelines on the use of radiation therapy for prostate cancer?

Key Message

One health technology assessment, nine systematic reviews (including one systematic review with meta-analysis and one network meta-analysis), and four randomized controlled trials were identified regarding the clinical effectiveness of radical prostatectomy or radiation therapy for early-stage or screen-detected prostate cancer. In addition, ten evidence-based guidelines were identified regarding the use of radical prostatectomy or radiation therapy for prostate cancer.