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We found 236 result(s)

esketamine hydrochloride (Spravato)

Last Updated: December 18, 2020
Result type: Reports
Product Line: Reimbursement Review
Generic Name: esketamine hydrochloride
Indications: Indicated in combination with a SSRI or SNRI, for the treatment of major depressive disorder in adults who have not responded adequately to at least two separate courses of treatment with different antidepressants, each of adequate dose and duration, in the current moderate to severe depressive episode.

  • Brand Name: Spravato
  • Manufacturer: Janssen Inc.
  • Project Number: SR0621-000
  • Project Status: Active
  • Submission Type: Initial

Care for Acquired Brain Injury and Concurrent Mental Health and Substance Use Issues

Last Updated: November 5, 2020
Result type: Reports
Product Line: Environmental Scans

CADTH is undertaking an Environmental Scan of systems and services that are in place in Canada for caring for individuals affected by acquired brain injury (ABI) and concurrent mental health and/or substance use issues. This project is being conducted to help inform decision-making and support practice change to improve the health and well-being...

  • Project Number: ES0339-000

vortioxetine hydrobromide (Trintellix )

Last Updated: April 8, 2020
Result type: Reports
Product Line: Reimbursement Review
Generic Name: vortioxetine hydrobromide
Indications: Major depressive disorder (MDD), adults.

  • Brand Name: Trintellix
  • Manufacturer: Lundbeck Canada Inc.
  • Project Number: SR0611-000
  • Project Status: Complete
  • Submission Type: Initial

Major Depressive Disorder – Focused Critical Appraisal of a Network Meta-Analysis

Last Updated: February 18, 2020
Result type: Reports
Product Line: Technology Review
Research Type: Drug

Major depressive disorder (MDD) is a common, debilitating, and recurrent mental health disorder. Over the past decades, multiple classes of antidepressant drugs have been developed to treat this condition. The relative effectiveness and safety of antidepressants are uncertain. This project will review a recently published network meta-analysis f...

  • Project Number: HE0022-000