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Reports

We found 193 result(s)

Biomarker-Based Point-of-Care Tests for the Evaluation of Mild Traumatic Brain Injury

Last Updated: June 23, 2020
Result type: Reports
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Methods CADTH Horizon Scanning bulletins present an overview of the technology and available evidence on a given topic. They are not systematic reviews and do not involve the critical appraisal of all studies or include a detailed summary of study findings. They are not intended to provide recommendations for or against a particular technology....

  • Project Number: EH0084-000

Small Molecule Calcitonin Gene-Related Peptide Receptor Antagonists for the Acute Treatment of Migraine

Last Updated: March 19, 2020
Result type: Reports
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Migraine is a common neurological disease and one of the leading causes of disability. The majority of adults with migraine use medications for their migraine attacks. Triptans are the most commonly used medication for moderate to severe attacks. However, for one-third of people with migraine, triptans are not effective, have decreased respon...

  • Project Number: EH0081-000

Early Identification of Ischemic Stroke

Last Updated: March 19, 2020
Result type: Reports
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Summary Every year in Canada, there are more than 50,000 strokes and 14,000 deaths from stroke. Ischemic stroke is the most common type of stroke: 85% of strokes are ischemic. There are effective treatments for ischemic stroke: endovascular treatment (mechanical thrombectomy) and medical thrombolysis with intravenous tissue plasminogen ac...

  • Project Number: EH0080-000

Endobronchial Valves for the Treatment of Severe Emphysema

Last Updated: March 19, 2020
Result type: Reports
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Summary Endobronchial valves are one-way valves placed in the airways of the most damaged parts of the lungs using bronchoscopy. Endobronchial valves may be used as an alternative to surgery to achieve lung volume reduction and improve breathing in some people with severe emphysema. Careful patient selection is critical to ensure that only ...

  • Project Number: EH0083-000

Lasmiditan for the Acute Treatment of Migraine

Last Updated: March 17, 2020
Result type: Reports
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Methods These bulletins are not systematic reviews and do not involve critical appraisal or include a detailed summary of study findings. Rather, they present an overview of the technology and available evidence. They are not intended to provide recommendations for or against a technology. Literature Search Strategy A limited literature searc...

  • Project Number: EH0082-000

Minimally invasive therapies for benign prostatic hyperplasia (BPH)

Last Updated: February 18, 2020
Result type: Reports
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Summary This bulletin builds on a CADTH Rapid Response Report that critically appraises recent evidence on treatments to alleviate lower urinary tract symptoms caused by benign prostatic hyperplasia (BPH). The focus of this bulletin is on four treatments: prostatic urethral lift (the UroLift system) water vapour thermal therapy (the R...

  • Project Number: EH0078-000

Magnetic Resonance-Guided Radiotherapy: MR-Simulation and MR-Linac

Last Updated: January 16, 2020
Result type: Reports

Radiotherapy is an important treatment tool used for two-thirds of people who receive cancer treatment. Magnetic resonance imaging (MRI) is being used for treatment guidance because it offers superior soft tissue contrast, which can reduce toxicity to organs at risk and to healthy tissue. Newer magnetic resonance (MR) systems — magnetic resonanc...

  • Project Number: EH0074-000

Inclisiran: A Small Interfering RNA Molecule for Treating Hypercholesterolemia

Last Updated: December 9, 2019
Result type: Reports
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Atherosclerotic cardiovascular disease (ASCVD) remains one of the leading causes of death in Canada. Cholesterol, specifically low-density lipoprotein cholesterol (LDL-C), is a major risk factor for cardiovascular disease (CVD) and is thereby targeted to reduce the likelihood of a cardiovascular event, such as a myocardial infarction (MI) and...

  • Project Number: EH0076-000

An Overview of Liquid Biopsy for Screening and Early Detection of Cancer

Last Updated: November 14, 2019
Result type: Reports
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Summary Currently, population-based cancer screening is limited to select cancers (e.g., cervical cancer). Cancer diagnoses are confirmed using tissue biopsies in solid tumours.1 However, these biopsies are invasive; associated with multiple complications;2 and are limited by the anatomical location of the tumour,3 the evolutio...

  • Project Number: EH0077-000