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Low molecular weight heparins for major orthopedic surgery: a case for clinical outcomes

Last Updated: January 1, 1998
Result type: Reports
Product Line: Health Technology Assessment, Technology Overviews

Cite as: Shukla VK, Otten N. Low molecular weight heparins for major orthopedic surgery: a case for clinical outcomes. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1998. The Issue Total hip or knee replacement with artificial joints (arthroplasty) are common surgical procedures. In Ontario alone (1996/97), t...

Comparison of Drug Treatments for Multiple Sclerosis

Last Updated: January 1, 1998
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Cite as: Otten N. Comparison of drug treatments for multiple sclerosis. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1998. This rapid assessment brings together the major studies involving the four drugs available in various countries for the treatment of MS: Avonex® (interferon beta 1-a), Rebif® (interferon b...

A review of therapies for attention-deficit/hyperactivity disorder

Last Updated: January 1, 1998
Result type: Reports

Cite as: Miller A, Lee S, Raina P, Klassen A, Zupancic J, Olsen L. A review of therapies for attention-deficit/hyperactivity disorder. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1999. This is a report to the Canadian Coordinating Office for Health Technology Assessment which summarizes work completed between...

Economic evaluation comparing low molecular weight heparin with other modalities for the prevention of deep vein thrombosis and pulmonary embolism following total hip or knee arthroplasty

Last Updated: January 1, 1998
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Cite as: Anderson D, O'Brien B, Nagpal S. et al. Economic evaluation comparing low molecular weight heparin with other modalities for the prevention of deep vein thrombosis and pulmonary embolism following total hip or knee arthroplasty. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1998. Deep vein thrombosis i...

Leukoreduction: The techniques used, their effectiveness and costs

Last Updated: January 1, 1998
Result type: Reports

Cite as: Gibis B, Baladi JF. Leukoreduction: the techniques used, their effectiveness and costs. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA); 1998. Leukocytes, as part of transfusions, can cause a variety of side-effects such as febrile reactions, platelet refractoriness, and transmission of viruses like the c...

The Heart Laser: Transmyocardial Revascularization Treatment of Angina Pectoris

Last Updated: January 1, 1998
Result type: Reports

The Heart Laser™, a new surgical cardiac laser system, is used in the treatment of severe angina pectoris. The chest pain experienced by those with angina pectoris can be due to ischemic heart disease. Chest pain occurs when the heart muscle does not receive an adequate supply of oxygenated blood. This is often a result of cholesterol plaque ...

Herceptin: monoclonal antibody therapy for metastatic breast cancer

Last Updated: January 1, 1998
Result type: Reports

Herceptin® (Trastuzumab) anti-HER2 humanized monoclonal antibody is an intravenous injection developed by Genentech, Inc. for the treatment of metastatic breast cancer. Herceptin® inhibits cell growth by binding the Human Epidermal growth factor Receptor protein 2 (HER2) present in excessive amounts on the surface of some cancer cells. It is ...

A Clinical and Economic Evaluation of Selective Serotonin Reuptake Inhibitors in Major Depression

Last Updated: December 1, 1997
Result type: Reports
Product Line: Health Technology Assessment, Technology Overviews

This overview is based primarily on the technical reports "Selective Serotonin Reuptake Inhibitors (SSRIs) for Major Depression - Part 1: Evaluation of the Clinical Literature and Part II: The Cost-effectiveness of SSRIs in Treatment of Depression". Depression is a common psychiatric disorder which has significant health and cost implications f...