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Intravenous Immunoglobulin for Treatment of Idiopathic Thrombocytopenic Purpura: Economic and Health Service Impact Analyses

Published on: September 17, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Intravenous immunoglobulin (IVIg), a blood product containing pooled IgG immunoglobulins derived from human plasma. Condition Idiopathic thrombocytopenic purpura (ITP) caused by an abnormal immune response that leads to low platelet counts and bleeding. Issue Because of the growing use of IVIg in Canada (including off-label use), esca...

Tags

Blood, Bruise, Plasma, Platelet Count, Skin, Treatment, Idiopathic Thrombocytopenic Purpura, Intravenous Immunoglobulins, Blood

Octreotide for Endocrine, Oncologic, and Gastrointestinal Disorders: Systematic Review and Budget Impact Analysis

Published on: July 21, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technologies Octreotide, which is a synthetic analogue of somatostatin, inhibits endocrine and exocrine secretions. Condition Octreotide is approved by Health Canada for use in acromegaly, neuroendocrine tumours, pancreatic surgery, and emergency bleeding of gastroesophageal varices. Octreotide is also being used for other unapproved indications...

Tags

Octreotide, Sandostatin, Gastric Varix, Esophageal Varix, Pancreatectomy, Intestinal Obstruction, Carcinoma, Hepatoma, Pancreas Cancer, Pancreatic Neoplasms, Hyperinsulinism, Acromegaly, Diarrhea, Endocrine Glands, Esophageal and Gastric Varices, Exocrine Glands, Gastrointestinal Disorders, Functional, Carcinoma, Hepatocellular, Hepatocellular Carcinoma, Pancreatic Cancer, Short Bowel Syndrome, Somatostatin, Neuroendocrine Tumors, Surgery, Sandostatin LAR, Octreotide Acetate Omega, OCT-LA, OCT-SA, Endocrine, Oncologic, Oncology, Gastrointestinal, Acromegaly Acromégalie, Somatotropin hypersecretion syndrome, GH hypersecretion, Growth hormone hypersecretion, Esophageal and Gastric Varices Varices oesophagiennes et gastriques Esophageal and Gastric Varices, Neuroendocrine Tumors Tumeurs neuroendocrines GEPNET, Gastroenteropancreatic neuroendocrine tumours, Gastroenteropancreatic neuroendocrine tumors, Pancreatectomy Pancréatectomie Pancreatic surgery, Intestinal Obstruction Occlusion intestinale Bowel obstruction, Diarrhea Diarrhée diarrhea, Hepatocellular Carcinome hépatocellulaire Hepatocellular Carcinoma, Hepatomas, Hepatocellular neoplasms, Pancreatic Neoplasms Tumeurs du pancréas Pancreatic cancer, Hyperinsulinism Hyperinsulinisme Pediatric idiopathic hyperinsulinism, Pediatric persistent hyperinsulinism, Short Bowel Syndrome Syndrome de l'intestin court Short bowel syndrome

Short-Acting Agents for Procedural Sedation and Analgesia in Canadian Emergency Departments: A Review of Clinical Outcomes and Economic Evaluation

Published on: March 31, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Short-acting agents for procedural sedation and analgesia (PSAs) propofol, ketamine HCl, etomidate, and ketamine combined with low-dose propofol (ketofol). Condition Adults who present to emergency departments (EDs) for painful procedures (i.e., treatment for bone fractures, major joint dislocations, cardioversion, and other procedure...

Tags

Analgesia, Opioids, Canada, Emergency Care, Sedatives, Anesthesia, Short-Acting Agents for Procedural Sedation and Analgesia in Canadian Emergency Departments, A Review of Clinical Outcomes and Economic Evaluation

Erythropoiesis-Stimulating Agents for Anemia of Chronic Kidney Disease: Systematic Review and Economic Evaluation

Published on: March 11, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Erythropoiesis-stimulating agents (ESA), epoetin alpha (Eprex ®, Janssen-Ortho), darbepoetin (Aranesp ™, Amgen), and epoetin beta (NeoRecormon ®, Roche) Condition Adult patients with anemia of chronic kidney disease (CKD) who need or do not need dialysis. Issue ESAs are routinely used to treat anemia of chronic kidney disease (CKD), e...

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Erythropoietin, Chronic Kidney Failure, ESRD, Renal Failure, Economics, Anemia, Erythropoiesis Stimulating Agents, Kidney Failure, Chronic, Kidney/urologic, Recombinant Érythropoïétine recombinée Erythropoiesis-Stimulating Agents, ESA, darbepoetin, darbepoetin alfa, darbepoetin alpha, Aranesp, epoetin beta NeoRecormon, epoetin alpha, epoetin alfa, Eprex, Anemia Anémie Anemia, Anaemia, Anemic, Chronic Défaillance rénale chronique Chronic Kidney Disease, Chronic renal disease, Chronic renal failure, CKD, CRF, End stage kidney disease, End stage renal disease, Review Literature Revue de la littérature Systematic review, Clinical review, Economics Économie Economic evaluation, Economic analysis

Minimally Invasive Arthroplasty in the Management of Hip Arthritic Disease: Systematic Review and Economic Evaluation

Published on: February 12, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Minimally invasive total hip replacement (MI THR) procedures that involve single- and double- incision techniques. Condition Patients who are eligible for THR due to degenerative, rheumatoid, or other arthritic diseases of the hip. Issue Emerging minimally invasive surgical techniques for hip replacement require specialized equipment....

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Arthroplasty, Hip, Minimally Invasive Surgical Procedures, Arthroplasty, Hip Replacement, Musculoskeletal, Minimally Invasive Arthroplasty in the Management of Hip Arthritic Disease, Systematic Review and Economic Evaluation

Real-Time (Synchronous) Telehealth in Primary Care: Systematic Review of Systematic Reviews

Published on: January 30, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Real-time telehealth involves the use of information and communication technologies (e.g., a minimum set of video cameras, computer displays, and a secure high-speed Internet connection) to enable individuals to communicate live (or synchronously) over long and short distances. Issue Although real-time telehealth has been used for at ...

Tags

Telehealth, Primary Care, Telehealth, Real-Time (Synchronous) Telehealth in Primary Care, Systematic Review of Systematic Reviews

Asynchronous Telehealth: Systematic Review of Analytic Studies and Environmental Scan of Relevant Initiatives

Published on: January 30, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Asynchronous telehealth refers to the storage of clinically important digital samples and relevant data (e.g., pictures of moles or surgical wounds and radiological images) from any location and forwarding them to a health care professional at a distant site for assessment at a convenient time. Issue Asynchronous telehealth could redu...

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Telehealth, Telehealth, Asynchronous Telehealth, Systematic Review of Analytic Studies and Environmental Scan of Relevant Initiatives

Telehealth for Acute Stroke Management (Telestroke): Systematic Review of Analytic Studies

Published on: January 21, 2008
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology Any modality of telehealth (synchronous or asynchronous) that enables communication between a patient and health care providers, or among health care providers, for the purposes of assessing, treating, or rehabilitating stroke patients. Issue There is uncertainty about how telestroke programs can be optimally delivered. There have bee...

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Stroke, Telehealth, Stroke, Telehealth, Telehealth for Acute Stroke Management (Telestroke), Systematic Review of Analytic Studies

Recombinant human growth hormone for Turner syndrome: systematic review and economic evaluation

Published on: December 21, 2007
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports

Technology and Condition Recombinant human growth hormone (rhGH) for treatment of Turner syndrome (TS). Issue Given the high cost of rhGH treatment and the evolving evidence base for its clinical effect in patients with TS, policy makers need evidence
to inform reimbursement decisions about rhGH. Methods and Results A systematic review was...

Tags

Growth Hormone, Somatropin, Humatrope, Serostim, Saizen, Nutropin, Economics, Genetics, Recombinant Growth Hormone, Turner Syndrome, Human Growth Hormone, Genetics, Recombinant human growth hormone for Turner syndrome, systematic review and economic evaluation Turner Syndrome Syndrome de Turner Turner syndrome, Turner’s syndrome, Turners syndrome, Human Growth Hormone Hormone de croissance humaine Recombinant human growth hormone, rhGH, Review Literature Revue de la littérature Systematic review, Clinical review, Economics Économie Economic evaluation, Economic analysis, Revue de la littérature, Systematic review, Clinical review, Économie, Economic evaluation, Economic analysis

Adalimumab, Alefacept, Efalizumab, Etanercept, and Infliximab for Severe Psoriasis Vulgaris in Adults: Budget Impact Analysis and Review of Comparative Clinical- and Cost-Effectiveness

Published on: December 21, 2007
Result type: Reports
Product Line: Health Technology Assessment, Technology Reports
Research Type: Drug

Tags

Dermatology, Psoriasis, Skin Abnormalities, Skin Diseases, Dermatology, Adalimumab, Alefacept, Efalizumab, Etanercept, and Infliximab for Severe Psoriasis Vulgaris in Adults, Budget Impact Analysis and Review of Comparative Clinical- and Cost-Effectiveness, ***, ***,