Background and Context The purpose of this Environmental Scan is to provide an overview of the current and projected use of companion diagnostic tests required for the prescription of targeted drug...

Context An increasing number of patients with end stage kidney disease (ESKD) are being initiated on long-term dialysis every year in Canada.1 According to data published by the Canadian Institute for...

Abbreviations ALC alternate level of care ARP alternative relationship plan CACS Comprehensive Ambulatory Care Classification System CAT Cost Analysis Tool CIHI Canadian Institute for Health...

Context Proton beam therapy (PBT) has been described as a technological innovation that may have the potential to disrupt and transform approaches to cancer treatment. However, its high cost and an...

The number of drugs available for sedation of patients in the intensive care unit (ICU) is limited, with both benzodiazepines and propofol being commonly used. Dexmedetomidine is a selective alpha-2...

Context Pediatric feeding and swallowing assessment services are concerned with evaluating and diagnosing children who experience difficulty eating, drinking, and swallowing (also known as dysphagia)...

Context Health Technology Assessment (HTA) informs health care decision-makers about the value — such as the safety, efficacy, and cost-effectiveness — of new and existing health technologies. HTA can...

Key Messages For rheumatoid arthritis patients with moderate to severe disease in whom treatment with methotrexate has failed or who are intolerant to methotrexate, conventional synthetic disease...

Obstructive sleep apnea (OSA), a sleep disorder in which breathing stops and starts, can lead to serious health complications such as fatigue, hypertension, cardiovascular events, and diabetes. OSA...

Venous thromboembolic events (VTEs) include both deep vein thrombosis (DVT) and pulmonary embolism (PE). VTEs represent an important disease burden in Canada; they are common and likely to increase as...