Summary Barrett esophagus, also called Barrett’s esophagus (BE), can be a precursor to esophageal adenocarcinoma — the most common type of esophageal cancer in Canada. Identifying individuals with BE...

This bulletin was originally published in May 2015. In July 2015, minor changes in wording were made on page 2 (paragraphs 3, 4, and 7), and on page 6 (paragraph 3) at the request of the manufacturer...

This Horizon Scanning report summarizes information regarding an emerging health technology — the Portable Neuromodulation Simulator, or PoNS — designed to supplement physical therapy and improve...

Severe coronavirus disease 2019 (COVID-19) illness has been associated with high levels of cytokines — small proteins in the blood that both promote and control inflammation.1-3 Instead of enhancing...

This issue of Health Technology Update features brief summaries of information on a range of technologies that aim to support the prevention, identification, and management of COVID-19 — from...

Summary This bulletin builds on a CADTH Rapid Response Report that critically appraises recent evidence on treatments to alleviate lower urinary tract symptoms caused by benign prostatic hyperplasia...

Summary Currently, population-based cancer screening is limited to select cancers (e.g., cervical cancer). Cancer diagnoses are confirmed using tissue biopsies in solid tumours.1 However, these...

Radiotherapy is an important treatment tool used for two-thirds of people who receive cancer treatment. Magnetic resonance imaging (MRI) is being used for treatment guidance because it offers superior...

Summary Dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists are classes of medications used in diabetes...

Summary Major depressive disorder (MDD) is a common, debilitating, and recurrent mental health disorder. Approximately 10% to 30% of patients with MDD will not reach complete clinical remission...