Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, in which the immune system causes an inflammatory response that damages or destroys myelin, axons, and...

Primary membranous nephropathy (PMN) is an autoimmune disease that commonly presents as nephrotic syndrome. The treatment goal of patients with PMN is to induce remission. Current treatment options...

Immune thrombocytopenia (ITP) is a disorder characterized by low platelets and an increase in bleeding risk due to increased platelet destruction and impaired platelet production. This project will...

Diabetes mellitus is a group of metabolic disorders in which the body either does not produce enough insulin (type 1 diabetes) or does not properly use the insulin it produces (type 2 diabetes)...

CADTH undertook a health technology assessment (HTA) to assess the evidence on proton beam therapy (PBT) for various types of cancer and to identify the issues related to referring patients abroad for...

Key Messages Dental restorations with dental amalgam last longer and cost less compared with restorations with composite resins. The evidence shows no clinically important differences in the safety of...

Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) are the most commonly reported sexually transmitted infections in Canada. Untreated infections are associated with added substantial morbidity...

CADTH assessed the clinical effectiveness and safety of formal peer support programs for youth mental health to support decision-making about adopting, implementing, and evaluating formal peer support...

People living in rural areas often face difficulties when accessing health care. Due to the challenges with providing care in rural areas, various strategies have been proposed and implemented to help...