Tisagenlecleucel is a chimeric antigen receptor (CAR) T-cell therapy for the treatment of adults with relapsed or refractory diffuse large B-cell lymphoma and children and young adults with relapsed...

Post-Traumatic Stress Disorder (PTSD) occurs as a response to an acute traumatic event or an extreme stressor. Symptoms include fear, helplessness, hyperarousal, re-experiencing of the event, and...

Worldwide, cervical cancer is one of the most frequently diagnosed cancers; however, the incidence of cervical cancer has been decreasing in the past three decades, largely due to routine screening...

CADTH undertook a health technology assessment (HTA) to inform decision-making about the appropriate use of dialysis modalities for the treatment of end-stage kidney disease (ESKD). The HTA addressed...

Obstructive sleep apnea (OSA), a sleep disorder in which breathing stops and starts, can lead to serious health complications such as fatigue, hypertension, cardiovascular events, and diabetes. OSA...

Pulmonary embolism (PE) is a blockage of one of the arteries in the lung, frequently caused by a blood clot that has travelled to the lung from another part of the body. If left untreated, it can be...

Hybrid closed-loop insulin delivery systems (HCLs) are an emerging technology for the management of type 1 diabetes. HCLs combine an insulin pump with a continuous glucose monitor (CGM) and a computer...

Glaucoma is a leading cause of blindness. A range of surgical interventions exist for treating glaucoma, including a group of procedures commonly called micro-invasive or minimally invasive glaucoma...

Axicabtagene ciloleucel is a chimeric antigen receptor T-cell therapy for the treatment of adult patients with relapsed or refractory large B-cell lymphoma. This includes diffuse large B-cell lymphoma...

A growing evidence base suggests that autologous hematopoietic stem cell transplant (AHSCT) is a clinically effective emerging intervention for treating multiple sclerosis (MS), particularly for...