Osteoporosis is a systemic skeletal disease characterized by a loss of bone mass and an increased risk of fragility fractures. Osteoporosis is highly prevalent, affecting an estimated 1.5 million...

The CADTH pCODR Expert Review Committee (pERC) has issued reimbursement recommendations on immunotherapies (ipilimumab, pembrolizumab, nivolumab, and nivolumab plus ipilimumab) and BRAF mutation...

In 2018, there were close to 62,000 people living with HIV in Canada. As antiretroviral therapies (ARTs) have become easier to access, administer and monitor, and effectiveness has improved, HIV has...

Chronic pain is defined as pain lasting longer than 3 months, and it affects approximately 19% of adults in Canada. In 2021, CADTH completed an Environmental Scan entitled Models of Care for Chronic...

This report identifies and summarizes published guidance from Canadian jurisdictions that provide recommendations regarding which pharmacological therapies should (or should not) be used to treat...

This is a collaborative health technology assessment with Ontario Health. Mammography (i.e., X-ray of the breast) is used for breast cancer screening in people at average risk for breast cancer. The...

As the number of Canadians living with dementia rises, so does the demand for dementia-related care across the country. CADTH facilitated a roundtable discussion to hear about patients’ and caregivers...

Nirmatrelvir and ritonavir are oral medications given in combination to treat Covid-19. Specifically, these medications are used to treat mild to moderate COVID-19 in patients with confirmed SARS-CoV...

Biologics require formulary management strategies upon loss of exclusivity (i.e., data protection and/or patent expiry) to manage expenditures due to a lack of or delay in biosimilar development and...

Laboratory tests are a standard part of routine health care. However, overutilization of low-value laboratory tests can lead to unnecessary interventions or investigations and increased health care...