Therapeutic Drug Monitoring of Vancomycin: Clinical Evidence and Cost-Effectiveness

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Reference List
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Reference List
Project Number:
RA1031-000

Question

  1. What is the clinical evidence regarding using area under the curve to a minimum inhibitory concentration ratio versus trough level dosing for the administration of vancomycin?
  2. What is the cost-effectiveness of therapeutic drug monitoring of vancomycin using area under the curve to a minimum inhibitory concentration ratio versus trough level for people with serious infections?

Key Message

Two non-randomized studies were identified regarding the clinical effectiveness of therapeutic drug monitoring of vancomycin. No relevant economic evaluations were identified regarding cost-effectiveness of therapeutic drug monitoring of vancomycin.