Question
- What is the clinical effectiveness of topical antimicrobial use without wound dressing application on both infected and non-infected diabetic foot ulcers (DFU)?
- What is the clinical effectiveness of topical antimicrobial use with regular, non-antimicrobial wound dressing application on both infected and non-infected DFUs?
- What is the clinical effectiveness of antimicrobial dressing application on both infected and non-infected DFUs?
- What are the evidence-based guidelines regarding the use of antimicrobial products on DFUs in the absence of signs and symptoms of infection?
- What are the evidence-based guidelines regarding the use of topical antimicrobials and antimicrobial dressings for the management of DFUs?
Key Message
Six systematic reviews and meta-analyses, three randomized controlled trials, and three non-randomized studies were identified regarding the clinical effectiveness of topical antimicrobials or antimicrobial dressing application on both infected and non-infected DFUs. One evidence based guideline was identified regarding the use of topical antimicrobials and antimicrobial dressings for the management of DFUs.