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Topical Antimicrobials and Antimicrobial Dressings for the Management of Diabetic Foot Ulcers: Clinical Effectiveness and Guidelines

Published on: September 15, 2014
Project Number: RB0735-000
Product Line: Rapid Response
Research Type: Devices and Systems
Report Type: Summary of Abstracts
Result type: Report

Question

  1. What is the clinical effectiveness of topical antimicrobial use without wound dressing application on both infected and non-infected diabetic foot ulcers (DFU)?
  2. What is the clinical effectiveness of topical antimicrobial use with regular, non-antimicrobial wound dressing application on both infected and non-infected DFUs?
  3. What is the clinical effectiveness of antimicrobial dressing application on both infected and non-infected DFUs?
  4. What are the evidence-based guidelines regarding the use of antimicrobial products on DFUs in the absence of signs and symptoms of infection?
  5. What are the evidence-based guidelines regarding the use of topical antimicrobials and antimicrobial dressings for the management of DFUs?

Key Message

Six systematic reviews and meta-analyses, three randomized controlled trials, and three non-randomized studies were identified regarding the clinical effectiveness of topical antimicrobials or antimicrobial dressing application on both infected and non-infected DFUs. One evidence based guideline was identified regarding the use of topical antimicrobials and antimicrobial dressings for the management of DFUs.

Tags

ulcer, anti-infective agents, bandages, diabetes complications, diabetic foot, occlusive dressings, wound healing, wounds and injuries, diabetes, Ulceration, Local