Last Updated : February 2, 2015
Details
FilesProject Line:
Health Technology Review
Project Sub Line:
Summary with Critical Appraisal
Project Number:
RC0627-000
Question
- What is the clinical effectiveness of tramadol for the management of pain in adult patients?
Key Message
Systematic reviews and individual RCTs suggest greater pain reduction and more adverse events with tramadol and tramadol combination products compared with placebo. The differences, however, were not always statistically significant or statistical significance was not reported. Efficacy and safety results of tramadol or tramadol combinations compared with an active agent varied depending on the particular comparator agent. Results were from single RCTs or indirect comparison and need to be interpreted with caution.
Files
Last Updated : February 2, 2015