Weekly COVID-19 Update

CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 evidence portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and growing state of the international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.

Events

CADTH Webinar: How COVID-19 Is Changing the Evidence Landscape: October 20, 2020

You can still register for this no-cost special webinar marking the inaugural World Evidence-Based Healthcare Day. Speakers include Dr. Christopher McCabe (Executive Director and CEO, Institute of Health Economics); Anne Hayes (Director, Research, Analysis and Evaluation Branch, Ontario Ministry of Health and Co-Chair of the Evidence Synthesis Network, and Member of the COVID-19 Advisory for Ontario Science Table); and Dr. Nicole Mittmann (CADTH Chief Scientist and Vice-President, Evidence Standards).

CADTH Webinar: Open Science — COVID-19 and Beyond: October 27, 2020

There is still time to register for this no-cost talk about the many scientific publishing shifts happening in connection with the pandemic. Speakers include Leslie Weir (Librarian and Archivist of Canada; Chair, Open Science Roadmap Advisory Committee) and Dr. Margaret Sampson (Manager of Library Services, Children’s Hospital of Eastern Ontario).

Reports

Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19

• This report provides information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19.
• It will be updated every two weeks.
• Ongoing trials of vaccines and plasma-based therapies are addressed in separate CADTH reports.

Temperature, Humidity, and COVID-19: Evidence

• These citations related to weather and COVID-19 infection are intended to provide a preliminary quick start to enable more comprehensive searching, or to help frame questions or issues.
• If you would like to know more, please contact CADTH by email or our requests page.

COVID-19 News

• WHO Solidarity Trial: Remdesivir, Lopinavir/Ritonavir, Hydroxychloroquine, Interferon Beta-1a
  On October 15, 2020, interim study results from WHO’s Solidarity Trial were released in pre-print (ISRCTN83971151).
• Baricitinib
  On October 8, 2020, preliminary results of the Adaptive COVID-19 Treatment Trial (ACTT-2), sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) for the treatment of COVID-19, were released.
• Lopinavir-ritonavir
  On October 5, 2020, the results of the lopinavir-ritonavir arm of the Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial were published.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations, as well as from the Canadian federal, provincial, and territorial governments’ health jurisdictions:

• Pan-Canadian Health Organizations
• Federal, Provincial, and Territorial Information

CAN’T FIND WHAT YOU NEED? LET US KNOW

Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.

The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal. You’re receiving this update because you’ve subscribed to our CADTH e-alert system.