Renal cell carcinoma (RCC) is the most common type of kidney cancer and is often diagnosed at a later stage, which makes it difficult to treat. Recent advancements in systemic therapies, such as dual...
The objective of this review is to identify new evidence available since the 2019 Canadian Drug Expert Committee review for cerliponase alfa (Brineura) for the treatment of pediatric patients with...
Given the rapid growth in the prevalence of diabetes during pregnancy and the evolution of recommendations for treatments, contemporary data are needed on the use of antidiabetic drugs during...
Antipsychotic medications are sometimes used to treat the behavioural and psychological symptoms of dementia (e.g., responsive behaviours such as aggression, anxiety, or agitation) for people living...
Calcitonin gene-related peptide (CGRP) inhibitors are a migraine prophylaxis treatment for patients who have not responded to conventional migraine therapies. However, it is unclear whether trying...
This study analyzed trends in prescription opioid use for pain and opioid agonist therapy (OAT) from January 2018 to December 2022 across 6 Canadian provinces. A decline in new and overall...
This report aims to estimate the impacts of providing remdesivir as an inpatient treatment for COVID-19 in Canada on health system costs and health outcomes. The analyses presented in this report were...
This report aims to estimate the impacts of providing tocilizumab as a treatment for COVID-19 in Canada on health system costs and health outcomes. The analyses presented in this report were conducted...
This report aims to estimate the impacts of providing nirmatrelvir-ritonavir as an outpatient treatment for COVID-19 in Canada on health system costs and health outcomes. The analyses presented in...
This report aims to estimate the impacts of providing remdesivir as an outpatient treatment for COVID-19 in Canada on health system costs and health outcomes. The analyses presented in this report...