Question
1. What is the clinical effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas?
2. What is the cost-effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas?
Key Message
• One health technology assessment, 4 systematic reviews (1 with network meta-analysis and 1 with meta-analysis), and 2 non-randomized studies were identified regarding the clinical effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas.
• One systematic review was identified regarding the cost-effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas