5-Aminolevulinic Acid Hydrochloride–Guided Surgical Resection of High-Grade Gliomas

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Project Status:
Completed
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Reference List
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Reference List
Project Number:
RA1184-000

Question

​1. What is the clinical effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas? 2. What is the cost-effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas?

Key Message

​• One health technology assessment, 4 systematic reviews (1 with network meta-analysis and 1 with meta-analysis), and 2 non-randomized studies were identified regarding the clinical effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas. • One systematic review was identified regarding the cost-effectiveness of 5-aminolevulinic acid hydrochloride–guided surgical resection for adults with suspected high-grade gliomas