A Therapeutic Review is an evidence-based review of publicly available sources regarding a therapeutic category of drugs (e.g., antihypertensive agents) or a class of drugs (e.g., angiotensin-converting enzyme inhibitors [ACEIs]) in order to support drug listing and policy decisions, as well as encouraging the optimization of drug therapy. The scope and depth of a Therapeutic Review are determined by customer needs. The final outputs of CADTH Therapeutic Reviews include a science report (clinical and economic reviews) and a recommendation report.
The Therapeutic Review Framework describes, in detail, the CADTH Therapeutic Review process. From time to time, CADTH may amend this framework in consultation with participating drug plans and stakeholders, if required.