CADTH | Evidence Driven
CADTH | Evidence Driven

Circulating Tumour DNA Testing for the Identification of Genetic Mutations: Diagnostic Test Accuracy and Clinical Utility

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1081-000

Question

  1. What is the diagnostic test accuracy of circulating tumour DNA testing for the identification of genetic mutations?
  2. What is the clinical utility of circulating tumour DNA testing for the identification of genetic mutations?
  3. What is the cost-effectiveness of circulating tumour DNA testing for the identification of genetic mutations?

Key Message

Four systematic reviews and meta-analyses, three randomized controlled trials, and 44 non-randomized studies were identified regarding the diagnostic test accuracy and clinical utility of circulating tumour DNA testing for the identification of genetic mutations.

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Circulating Tumour DNA Testing for the Identification of Genetic Mutations: Diagnostic Test Accuracy and Clinical Utility Rapid Response January 13, 2020 View PDF

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Last Updated : February 24, 2020