COVID-19 Update

( Last Updated : January 11, 2021)
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CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.


Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19

  • This report provides information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19.
  • It will be updated every 2 weeks.
  • Ongoing trials of vaccines and plasma-based therapies are addressed in separate CADTH reports.

Ongoing Trials of Plasma-Based Therapies for the Treatment of COVID-19

  • This report provides information on ongoing randomized controlled trials of intravenous immune globulin and hyperimmune globulin that are being investigated for the management of COVID-19.
  • It will be updated every month.
  • Ongoing trials of convalescent plasma are addressed in separate CADTH reports.

COVID-19 mRNA Vaccines for People With Cancer

  • The first 2 vaccines (both messenger ribonucleic acid — mRNA — vaccines) for the prevention of COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been authorized for emergency use.
  • People with cancer are at a higher risk for serious illness resulting from COVID-19, but were not specifically included in the trials that assessed the safety of the mRNA vaccines.
  • It is uncertain whether it is recommended or safe for this population to be among the first groups of people who get vaccinated.
  • Some countries, but not Canada at the time of this report, have included people with cancer as part of the groups being considered for priority access to COVID-19 vaccines.
  • Further study and information-gathering are still required.

COVID-19 News

Visit our news page to stay on top of all of the emerging information we are monitoring and updating.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:


Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.

The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal. You’re receiving this update because you’ve subscribed to our CADTH e-alert system.