COVID-19 Update


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CADTH is committed to supporting Canada’s health care decision-makers through this challenging and uncertain time.

Our COVID-19 Evidence Portal contains the latest COVID-19 information from CADTH and other respected organizations. Content is updated daily to reflect the rapidly changing and increasing international scientific evidence related to this disease.

The following is a summary of the most recent information posted to our COVID-19 portal.


Ongoing Trials for Drugs in the Prevention and Treatment of COVID-19

  • This report provides information on ongoing randomized controlled trials of drugs being investigated to treat or prevent COVID-19.
  • It will be updated every two weeks.
  • Ongoing trials of vaccines and plasma-based therapies are addressed in separate CADTH reports.

Virus-Neutralizing Monoclonal Antibodies Against SARS-CoV-2

  • This Horizon Scan report explores what we know about virus-neutralizing monoclonal antibodies, their mechanism of action and how they are administered, and which virus-neutralizing monoclonal antibodies are in clinical development for SARS-CoV-2 infection.

COVID-19 Testing: A Summary of Testing Methods

  • This report provides an overview of testing methods for COVID-19.
  • A description of published clinical evidence and important considerations related to the potential implementation of these tests are provided.
  • As demands for testing during the pandemic increases, this information may be of interest to health care decision-makers interested in learning more about the availability and variety of testing types and screening methods.

COVID-19 News

Visit our news page to stay on top of all of the emerging information we are monitoring and updating. Here are the highlights of the latest news:

  • Health Canada Authorizes Pfizer-BioNTech COVID-19 Vaccine, Tozinameran (BNT162b2)
    On December 9, 2020, Health Canada issued an authorization with conditions under the COVID-19 Interim Order for the mRNA-based Pfizer-BioNTech COVID-19 Vaccine, Tozinameran.
  • COVID-19 Vaccine Candidate: ChAdOx1 nCoV-19 (AZD1222)
    On November 19, 2020, preliminary findings were published of a single-blind, randomized, controlled, phase II/III trial (NCT04400838) investigating the adenovirus-vectored vaccine ChAdOx1 nCoV-19 compared with a control vaccine, MedACW.

CADTH Literature Searching Tools

To help conduct your COVID-19–related literature searches, see our COVID-19 Search Strings and our COVID-19 Grey Literature Resources.

Additional Resources

CADTH is pleased to showcase additional COVID-19 resources from our partner organizations and the Canadian federal, provincial, and territorial governments’ health jurisdictions:

  • Pan-Canadian Health Organizations
  • Federal, Provincial, and Territorial Information


Canadian ministries and departments of health, publicly funded organizations responsible for health service delivery, and clinical society stakeholders are encouraged to submit a request or contact their CADTH Liaison Officer. We’re here to help.

The CADTH Weekly COVID-19 Update is intended to keep you informed about the latest information posted on the CADTH COVID-19 portal. You’re receiving this update because you’ve subscribed to our CADTH e-alert system.