Direct Observational Therapy for the Treatment of Tuberculosis: Clinical Evidence and Guidelines


( Last Updated : May 12, 2020)
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1475-000

Details


Question


  1. What is the clinical evidence regarding the provision of direct observational therapy for the treatment of tuberculosis?

  2. What are the evidence-based guidelines regarding the use of direct observational therapy for the treatment of tuberculosis?


Key Message

Eight systematic reviews (seven with meta-analyses), five randomized controlled trials and eight non-randomized studies were identified regarding the provision of direct observation therapy for treatment of tuberculosis. Additionally, eight evidence-based guidelines were identified regarding the use of direct observational therapy for the treatment of tuberculosis.