Discontinuation of Cholinesterase Inhibitors in Adults with Dementia: Clinical Effectiveness and Guidelines


( Last Updated : November 13, 2019)
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1408-000

Details


Question


  1. What is the clinical effectiveness of discontinuing cholinesterase inhibitors in adults who have dementia?

  2. What are the evidence-based guidelines for discontinuing cholinesterase inhibitors in adults who have dementia?


Key Message

One systematic review with meta-analysis and five randomized controlled trials were identified regarding the clinical effectiveness of discontinuing cholinesterase inhibitors in adults who have dementia. Three evidence-based guidelines were identified regarding discontinuing cholinesterase inhibitors in adults who have dementia.