Duration of Bisphosphonate Treatment for Patients with Osteoporosis: Clinical Evidence and Guidelines


( Last Updated : August 22, 2019)
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1059-000

Details


Question


  1. What is the clinical evidence for varying treatment duration and courses of bisphosphonates for osteoporosis?

  2. What are the evidence-based guidelines regarding length of treatment with bisphosphonates for osteoporosis?


Key Message

One health technology assessment, six systematic reviews (one with meta-analyses), three randomized controlled trials, and five non-randomized studies were identified regarding the clinical evidence for varying treatment duration and courses of bisphosphonates for osteoporosis. Six evidence-based guidelines were identified regarding the length of treatment with bisphosphonates for osteoporosis.