Question
- What is the clinical effectiveness of e-therapy for the treatment of patients with depression?
Key Message
Evidence from a small number of systematic reviews (SRs) and small size randomized controlled trials (RCTs) consistently showed that therapist-guided e-therapy was superior to no treatment, wait list, or TAU in reducing depressive symptoms on patients with depression and major depressive disorder. Therapist-guided e-therapy was found to be equivalent to standard face-to-face CBT for patients with MDD, and the combination of e-therapy and TAU was equivalent to TAU alone in patients with depression.