Evusheld (Tixagevimab and Cilgavimab) for the Pre-exposure Prophylaxis of COVID-19 in Adults and Adolescents (≥ 12 Years of Age and Weighing at Least 40 kg)


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Health Technology Review
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Technology Review
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Tixagevimab and cilgavimab (Evusheld) is a combination of long-acting monoclonal antibodies for intramuscular administration that provides pre-exposure prophylaxis against COVID-19 for people at risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who have not had a known recent exposure to an individual infected with SARS-CoV-2. CADTH conducted a review of the evidence and convened an Implementation Advice Panel to prioritize the patient populations that are most likely to benefit from pre-exposure prophylaxis with Evusheld.