Gabapentin, Phenobarbital, Diazepam, and Lorazepam for the Treatment of Alcohol Withdrawal: Clinical Effectiveness and Guidelines


( Last Updated : June 24, 2020)
Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1498-000

Details


Question


  1. What is the clinical effectiveness of gabapentin, phenobarbital, diazepam, and lorazepam for the management of individuals with alcohol withdrawal?

  2. What are the evidence-based guidelines regarding the management of individuals with alcohol withdrawal in the emergency department?

  3. What are the evidence-based guidelines regarding the provision of addiction services to vulnerable populations with alcohol withdrawal during the coronavirus pandemic?


Key Message

Two systematic reviews and eleven non-randomized studies were identified regarding the clinical effectiveness of gabapentin, phenobarbital, diazepam, and lorazepam for the management of individuals with alcohol withdrawal. Four evidence-based guidelines were identified regarding the management of individuals with alcohol withdrawal in the emergency department. No relevant evidence-based guidelines were identified regarding the provision of addiction services to vulnerable populations with alcohol withdrawal during the coronavirus pandemic.