Hyaluronic Acid Injection for Facial Grooves or Wrinkles: Clinical Effectiveness, Safety, and Guidelines

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Project Status:
Completed
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Summary of Abstracts
Project Number:
RB1315-000 - RA1017-000

Question

  1. What is the clinical effectiveness of injected hyaluronic acid for facial grooves or wrinkles?
  2. What is the safety of injected hyaluronic acid for facial grooves or wrinkles?
  3. What are the evidence-based guidelines regarding injected hyaluronic acid for facial grooves or wrinkles?

Key Message

One systematic review and 20 randomized controlled trials were identified regarding the the clinical effectiveness and safety of injected hyaluronic acid for facial grooves or wrinkles. No relevant evidence-based guidelines were identified.